UY35359A - 7-OXO-PIRIDO [2,3-d] SUBSTITUTED PYRIMIDINS AND METHODS OF USE - Google Patents

7-OXO-PIRIDO [2,3-d] SUBSTITUTED PYRIMIDINS AND METHODS OF USE

Info

Publication number
UY35359A
UY35359A UY0001035359A UY35359A UY35359A UY 35359 A UY35359 A UY 35359A UY 0001035359 A UY0001035359 A UY 0001035359A UY 35359 A UY35359 A UY 35359A UY 35359 A UY35359 A UY 35359A
Authority
UY
Uruguay
Prior art keywords
methods
pirido
pyrimidins
oxo
substituted
Prior art date
Application number
UY0001035359A
Other languages
Spanish (es)
Inventor
Brown James
Thomas T Nguyen
Jian J Chen
Hong Fang-Tsao
Ryan Wurz
Andrew Tasker
Seifu Tadesse
Liping H Pettus
Bradley J Herberich
Harrington Essa
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of UY35359A publication Critical patent/UY35359A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invención comprende compuestos, análogos, profármacos y sales farmacéuticamente aceptables de estos, composiciones farmacéuticas, usos y métodos para la profilaxis y el tratamiento del cáncer.The invention comprises compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions, uses and methods for the prophylaxis and treatment of cancer.

UY0001035359A 2013-03-01 2014-02-28 7-OXO-PIRIDO [2,3-d] SUBSTITUTED PYRIMIDINS AND METHODS OF USE UY35359A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361771582P 2013-03-01 2013-03-01
US201361900156P 2013-11-05 2013-11-05

Publications (1)

Publication Number Publication Date
UY35359A true UY35359A (en) 2014-09-30

Family

ID=50288304

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001035359A UY35359A (en) 2013-03-01 2014-02-28 7-OXO-PIRIDO [2,3-d] SUBSTITUTED PYRIMIDINS AND METHODS OF USE

Country Status (7)

Country Link
EP (1) EP2961750A1 (en)
JP (1) JP2016510029A (en)
AU (1) AU2014223396A1 (en)
CA (1) CA2903040A1 (en)
TW (1) TW201522332A (en)
UY (1) UY35359A (en)
WO (1) WO2014134308A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2954189A1 (en) 2014-07-26 2016-02-04 Sunshine Lake Pharma Co., Ltd. 2-amino-pyrido[2,3-d]pyrimidin-7(8h)-one derivatives as cdk inhibitors and uses thereof
JP2018515524A (en) * 2015-05-12 2018-06-14 カリーラ ファーマシューティカルズ，インク． Bicyclic compound
CN106632313B (en) * 2016-03-04 2021-04-09 上海贤鼎生物科技有限公司 Important intermediate of anticancer drug palbociclib and synthesis process
CN111902413B (en) 2018-03-09 2023-10-17 里科瑞尔姆Ip控股有限责任公司 Substituted 1, 2-dihydro-3H-pyrazolo [3,4-d ] pyrimidin-3-ones
KR102328435B1 (en) * 2018-09-11 2021-11-18 재단법인 대구경북첨단의료산업진흥재단 Novel pyrido-pyrimidine derivatives, preparation method thereof, and pharmaceutical composition for use in preventing or treating protein kinase related disease containing the same as an active ingredient
US11697648B2 (en) 2019-11-26 2023-07-11 Theravance Biopharma R&D Ip, Llc Fused pyrimidine pyridinone compounds as JAK inhibitors
WO2022188755A1 (en) * 2021-03-08 2022-09-15 暨南大学 Pyridopyrimidine-based compound and application thereof
CN114210238A (en) * 2021-12-02 2022-03-22 上海旭东海普南通药业有限公司 Fluorouracil refining method and device

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101955914B1 (en) * 2008-06-27 2019-03-11 셀젠 카르 엘엘씨 Heteroaryl compounds and uses thereof
US8619856B2 (en) 2008-10-03 2013-12-31 Qualcomm Incorporated Video coding with large macroblocks
CN102482277B (en) * 2009-05-05 2017-09-19 达纳-法伯癌症研究所有限公司 Epidermal growth factor receptor inhibitor and the method for treating obstacle
ES2665013T3 (en) 2010-11-10 2018-04-24 Celgene Car Llc EGFR selective mutant inhibitors and uses thereof
CN102816162B (en) * 2011-06-10 2016-04-27 中国科学院广州生物医药与健康研究院 Pyrimido-pyrimidine ketone compounds and medicinal compositions thereof and application
WO2013170671A1 (en) * 2012-05-14 2013-11-21 华东理工大学 Pteridine ketone derivative and applications thereof as egfr, blk, and flt3 inhibitor
CN103012399B (en) * 2012-11-22 2015-06-17 中国科学院广州生物医药与健康研究院 7-oxopyridinopyrimidine compound as well as medicinal composition and application thereof

Also Published As

Publication number Publication date
JP2016510029A (en) 2016-04-04
AU2014223396A1 (en) 2015-08-27
WO2014134308A1 (en) 2014-09-04
EP2961750A1 (en) 2016-01-06
CA2903040A1 (en) 2014-09-04
TW201522332A (en) 2015-06-16

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Legal Events

Date Code Title Description
104 Application deemed to be withdrawn (no substantive examination fee paid)

Effective date: 20150710