CL2017000984A1 - Reducción de la viscosidad de formulaciones farmacéuticas - Google Patents

Reducción de la viscosidad de formulaciones farmacéuticas

Info

Publication number
CL2017000984A1
CL2017000984A1 CL2017000984A CL2017000984A CL2017000984A1 CL 2017000984 A1 CL2017000984 A1 CL 2017000984A1 CL 2017000984 A CL2017000984 A CL 2017000984A CL 2017000984 A CL2017000984 A CL 2017000984A CL 2017000984 A1 CL2017000984 A1 CL 2017000984A1
Authority
CL
Chile
Prior art keywords
viscosity
reduction
pharmaceutical formulations
pharmaceutical formulation
lylin
Prior art date
Application number
CL2017000984A
Other languages
English (en)
Spanish (es)
Inventor
Christopher James Sloey
Sekhar Kanapuram
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54427875&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2017000984(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of CL2017000984A1 publication Critical patent/CL2017000984A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CL2017000984A 2014-10-23 2017-04-20 Reducción de la viscosidad de formulaciones farmacéuticas CL2017000984A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462067637P 2014-10-23 2014-10-23

Publications (1)

Publication Number Publication Date
CL2017000984A1 true CL2017000984A1 (es) 2018-01-05

Family

ID=54427875

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2017000984A CL2017000984A1 (es) 2014-10-23 2017-04-20 Reducción de la viscosidad de formulaciones farmacéuticas
CL2019002190A CL2019002190A1 (es) 2014-10-23 2019-08-02 Reducción de la viscosidad de formulaciones farmacéuticas que comprende una proteína terapéutica a una concentración de al menos 70 mg/ml, donde la proteína terapéutica no es un anticuerpo (divisional solicitud 201700984)

Family Applications After (1)

Application Number Title Priority Date Filing Date
CL2019002190A CL2019002190A1 (es) 2014-10-23 2019-08-02 Reducción de la viscosidad de formulaciones farmacéuticas que comprende una proteína terapéutica a una concentración de al menos 70 mg/ml, donde la proteína terapéutica no es un anticuerpo (divisional solicitud 201700984)

Country Status (17)

Country Link
US (3) US11813328B2 (Direct)
EP (2) EP3909611B1 (Direct)
JP (3) JP2017531682A (Direct)
KR (1) KR102534017B1 (Direct)
CN (2) CN107206070B (Direct)
AU (2) AU2015335743B2 (Direct)
BR (1) BR112017008125B1 (Direct)
CA (1) CA2964786C (Direct)
CL (2) CL2017000984A1 (Direct)
EA (3) EA033444B1 (Direct)
ES (1) ES2964713T3 (Direct)
IL (2) IL287947B2 (Direct)
MA (1) MA54716A (Direct)
MX (2) MX388858B (Direct)
SG (1) SG11201703152RA (Direct)
WO (1) WO2016065181A1 (Direct)
ZA (1) ZA201702762B (Direct)

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JP7377596B2 (ja) 2017-02-22 2023-11-10 アムジエン・インコーポレーテツド 低粘度、高濃度エボロクマブ製剤及びそれらの製造方法

Also Published As

Publication number Publication date
AU2015335743A1 (en) 2017-05-04
US20170333559A1 (en) 2017-11-23
AU2021200990A1 (en) 2021-03-11
JP2017531682A (ja) 2017-10-26
MA54716A (fr) 2021-11-17
CN114569716A (zh) 2022-06-03
JP7411615B2 (ja) 2024-01-11
CA2964786A1 (en) 2016-04-28
EP3909611A1 (en) 2021-11-17
IL287947B1 (en) 2024-04-01
KR20170071518A (ko) 2017-06-23
BR112017008125A2 (pt) 2018-06-19
IL287947B2 (en) 2024-08-01
EP3909611B1 (en) 2023-08-30
US12318447B2 (en) 2025-06-03
MX2021015789A (es) 2022-01-27
IL251726B (en) 2021-12-01
CN107206070A (zh) 2017-09-26
US11813328B2 (en) 2023-11-14
US20250345421A1 (en) 2025-11-13
JP2020037559A (ja) 2020-03-12
ZA201702762B (en) 2022-12-21
MX388858B (es) 2025-03-20
AU2015335743B2 (en) 2020-12-24
WO2016065181A1 (en) 2016-04-28
IL251726A0 (en) 2017-06-29
EA033444B1 (ru) 2019-10-31
JP2022009223A (ja) 2022-01-14
EA201991447A1 (ru) 2019-11-29
EP3209332A1 (en) 2017-08-30
EA202191513A1 (ru) 2021-11-30
MX2017005243A (es) 2017-08-18
AU2021200990B2 (en) 2023-02-16
KR102534017B1 (ko) 2023-05-19
US20240066124A1 (en) 2024-02-29
EA038462B1 (ru) 2021-08-31
EA201790787A1 (ru) 2017-08-31
CL2019002190A1 (es) 2019-11-22
EP3209332B1 (en) 2021-05-26
ES2964713T3 (es) 2024-04-09
BR112017008125B1 (pt) 2023-11-21
JP6965321B2 (ja) 2021-11-10
CA2964786C (en) 2023-10-17
CN107206070B (zh) 2022-01-18
SG11201703152RA (en) 2017-05-30
IL287947A (en) 2022-01-01

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