MA54716A - Réduction de la viscosité de formulations pharmaceutiques - Google Patents

Réduction de la viscosité de formulations pharmaceutiques

Info

Publication number
MA54716A
MA54716A MA054716A MA54716A MA54716A MA 54716 A MA54716 A MA 54716A MA 054716 A MA054716 A MA 054716A MA 54716 A MA54716 A MA 54716A MA 54716 A MA54716 A MA 54716A
Authority
MA
Morocco
Prior art keywords
viscosity
reduction
pharmaceutical formulations
formulations
pharmaceutical
Prior art date
Application number
MA054716A
Other languages
English (en)
Inventor
Sekhar Kanapuram
Christopher James Sloey
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54427875&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA54716(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MA54716A publication Critical patent/MA54716A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA054716A 2014-10-23 2015-10-22 Réduction de la viscosité de formulations pharmaceutiques MA54716A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462067637P 2014-10-23 2014-10-23

Publications (1)

Publication Number Publication Date
MA54716A true MA54716A (fr) 2021-11-17

Family

ID=54427875

Family Applications (1)

Application Number Title Priority Date Filing Date
MA054716A MA54716A (fr) 2014-10-23 2015-10-22 Réduction de la viscosité de formulations pharmaceutiques

Country Status (17)

Country Link
US (2) US11813328B2 (fr)
EP (2) EP3209332B1 (fr)
JP (3) JP2017531682A (fr)
KR (1) KR102534017B1 (fr)
CN (2) CN107206070B (fr)
AU (2) AU2015335743B2 (fr)
BR (1) BR112017008125B1 (fr)
CA (1) CA2964786C (fr)
CL (2) CL2017000984A1 (fr)
EA (3) EA038462B1 (fr)
ES (1) ES2964713T3 (fr)
IL (2) IL287947B2 (fr)
MA (1) MA54716A (fr)
MX (2) MX2017005243A (fr)
SG (1) SG11201703152RA (fr)
WO (1) WO2016065181A1 (fr)
ZA (1) ZA201702762B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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EP3209332B1 (fr) 2014-10-23 2021-05-26 Amgen Inc. Réduction de la viscosité de formulations pharmaceutiques
EP3522918A1 (fr) 2016-10-06 2019-08-14 Amgen Inc. Formulations pharmaceutiques de protéines à viscosité réduite
JP7377596B2 (ja) * 2017-02-22 2023-11-10 アムジエン・インコーポレーテツド 低粘度、高濃度エボロクマブ製剤及びそれらの製造方法
AU2018258676B2 (en) 2017-04-28 2024-09-19 Amgen Inc. N-acetylated and non-acetylated dipeptides containing arginine to reduce the viscosity of viscous compositions of therapeutic polypeptides
WO2018200533A1 (fr) 2017-04-28 2018-11-01 Amgen Inc. Excipients pour réduire la viscosité de formulations d'anticorps et compositions de formulation
CA3063324A1 (fr) 2017-05-16 2018-11-22 Bhami's Research Laboratory, Pvt. Ltd. Formulations de proteines a haute concentration ayant une viscosite reduite
WO2019059302A1 (fr) * 2017-09-22 2019-03-28 旭化成ファーマ株式会社 Composition pharmaceutique liquide contenant du tériparatide ayant une excellente stabilité
WO2019106206A1 (fr) 2017-12-01 2019-06-06 Fyb 202 Project Gmbh Formulations liquides stables, à faible viscosité et à haute concentration en un anticorps anti-il-12/23p40
PE20210462A1 (es) 2018-07-05 2021-03-08 Bayer Ag METODO PARA LA PRODUCCION DE GRANULOS LIOFILIZADOS QUE COMPRENDEN UN ANTICUERPO ANTI-FACTOR XIa (FXIa) DE LA COAGULACION
EP3628683A1 (fr) * 2018-09-28 2020-04-01 Zealand Pharma A/S Formulations d'analogues de peptide-2 de type glucagon (glp-2)
AU2020263318A1 (en) * 2019-04-23 2021-10-21 Amgen Inc. The use of low molecular weight polyvinylpyrrolidone (PVP) to reduce viscosity of high concentration protein formulations

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US6767892B1 (en) * 1997-11-07 2004-07-27 Chrion Corporation Compositions providing for increased IGF-I solubility
DE69814133T2 (de) * 1997-11-07 2004-04-01 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Zusammensetzung um die löslichkeit von igf-i zu erhöhen
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
US6159485A (en) * 1999-01-08 2000-12-12 Yugenic Limited Partnership N-acetyl aldosamines, n-acetylamino acids and related n-acetyl compounds and their topical use
AU2001244584B2 (en) 2000-03-31 2006-01-19 Kirin Pharma Kabushiki Kaisha Powdery preparation for transmucosal administration containing a polymeric form of drug and exhibiting improved storage stability
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EP1589996A4 (fr) 2003-01-30 2009-01-21 Medimmune Inc Preparation d'anticorps anti-integrine alpha beta 3 et utilisations associees
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EP1841455A1 (fr) 2005-01-24 2007-10-10 Amgen Inc. Anticorps anti-amyloide humanise
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EP1977763A4 (fr) * 2005-12-28 2010-06-02 Chugai Pharmaceutical Co Ltd Préparation stabilisatrice contenant des anticorps
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EP2771033A4 (fr) * 2011-10-28 2016-02-17 Integritybio Inc Formulations protéiques contenant des acides aminés
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EP2863951A1 (fr) 2012-06-12 2015-04-29 Boehringer Ingelheim International GmbH Formulation pharmaceutique destinée à un anticorps thérapeutique
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TWI694836B (zh) 2014-05-16 2020-06-01 英商葛蘭素史克智慧財產管理有限公司 抗體調配物
EP3209332B1 (fr) 2014-10-23 2021-05-26 Amgen Inc. Réduction de la viscosité de formulations pharmaceutiques
BR112017010442A2 (pt) 2014-12-03 2017-12-26 Csl Behring Ag produto farmacêutico, usos de uma seringa de polímero, de um composto sequestrante de oxigênio, e de uma solução de imunoglobulina
MA46359A (fr) 2016-09-29 2019-08-07 Amgen Inc Protéines de liaison à l'antigène à viscosité faible et leurs procédés de préparation
EP3522918A1 (fr) 2016-10-06 2019-08-14 Amgen Inc. Formulations pharmaceutiques de protéines à viscosité réduite
JP7377596B2 (ja) 2017-02-22 2023-11-10 アムジエン・インコーポレーテツド 低粘度、高濃度エボロクマブ製剤及びそれらの製造方法

Also Published As

Publication number Publication date
AU2015335743A1 (en) 2017-05-04
US11813328B2 (en) 2023-11-14
SG11201703152RA (en) 2017-05-30
IL287947A (en) 2022-01-01
JP2022009223A (ja) 2022-01-14
EA038462B1 (ru) 2021-08-31
US20170333559A1 (en) 2017-11-23
CA2964786C (fr) 2023-10-17
JP2020037559A (ja) 2020-03-12
IL287947B1 (en) 2024-04-01
EP3209332B1 (fr) 2021-05-26
CN107206070A (zh) 2017-09-26
WO2016065181A1 (fr) 2016-04-28
CN114569716A (zh) 2022-06-03
EA033444B1 (ru) 2019-10-31
BR112017008125A2 (pt) 2018-06-19
AU2015335743B2 (en) 2020-12-24
EA202191513A1 (ru) 2021-11-30
CA2964786A1 (fr) 2016-04-28
JP6965321B2 (ja) 2021-11-10
EA201790787A1 (ru) 2017-08-31
KR102534017B1 (ko) 2023-05-19
EP3209332A1 (fr) 2017-08-30
IL287947B2 (en) 2024-08-01
ES2964713T3 (es) 2024-04-09
KR20170071518A (ko) 2017-06-23
CL2017000984A1 (es) 2018-01-05
BR112017008125B1 (pt) 2023-11-21
EP3909611A1 (fr) 2021-11-17
IL251726A0 (en) 2017-06-29
IL251726B (en) 2021-12-01
US20240066124A1 (en) 2024-02-29
EP3909611B1 (fr) 2023-08-30
MX2021015789A (es) 2022-01-27
JP7411615B2 (ja) 2024-01-11
ZA201702762B (en) 2022-12-21
AU2021200990B2 (en) 2023-02-16
EA201991447A1 (ru) 2019-11-29
CN107206070B (zh) 2022-01-18
AU2021200990A1 (en) 2021-03-11
MX2017005243A (es) 2017-08-18
JP2017531682A (ja) 2017-10-26
CL2019002190A1 (es) 2019-11-22

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