CL2015000383A1 - Kit farmaceutico que comprende al menos un agente farmaceutico activable capaz de causar un cambio celular predeterminado y por lo menos un agente modulador de la energía capaz de activar el agente farmaceutico. - Google Patents
Kit farmaceutico que comprende al menos un agente farmaceutico activable capaz de causar un cambio celular predeterminado y por lo menos un agente modulador de la energía capaz de activar el agente farmaceutico.Info
- Publication number
- CL2015000383A1 CL2015000383A1 CL2015000383A CL2015000383A CL2015000383A1 CL 2015000383 A1 CL2015000383 A1 CL 2015000383A1 CL 2015000383 A CL2015000383 A CL 2015000383A CL 2015000383 A CL2015000383 A CL 2015000383A CL 2015000383 A1 CL2015000383 A1 CL 2015000383A1
- Authority
- CL
- Chile
- Prior art keywords
- pharmaceutical
- agent capable
- pharmaceutical agent
- activating
- causing
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0066—Psoralene-activated UV-A photochemotherapy (PUVA-therapy), e.g. for treatment of psoriasis or eczema, extracorporeal photopheresis with psoralens or fucocoumarins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/008—Two-Photon or Multi-Photon PDT, e.g. with upconverting dyes or photosensitisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0656—Chemical light sources
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
- A61N2005/1089—Electrons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
- A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Radiology & Medical Imaging (AREA)
- Pathology (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Rehabilitation Therapy (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91066307P | 2007-04-08 | 2007-04-08 | |
US11/935,655 US9358292B2 (en) | 2007-04-08 | 2007-11-06 | Methods and systems for treating cell proliferation disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2015000383A1 true CL2015000383A1 (es) | 2015-04-24 |
Family
ID=39827110
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL200800997A CL2008000997A1 (es) | 2007-04-08 | 2008-04-07 | Metodo de tratamiento que comprende administrar un agente farmaceutico activable con capacidad de efectuar un cambio celular al activarse, aplicar una energia iniciadora, donde el cambio celular trata el trastorno de proliferacion celular; metodo de |
CL2015000383A CL2015000383A1 (es) | 2007-04-08 | 2015-02-17 | Kit farmaceutico que comprende al menos un agente farmaceutico activable capaz de causar un cambio celular predeterminado y por lo menos un agente modulador de la energía capaz de activar el agente farmaceutico. |
CL2015000382A CL2015000382A1 (es) | 2007-04-08 | 2015-02-17 | Composición farmacéutica que comprende al menos un agente farmacéutico activable capaz de causar un cambio celular predeterminado y un aditivo con efecto terapéutico; uso para tratar un trastorno de proliferación celular tal como cancer. (divisional solicitud n° 997-2008). |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL200800997A CL2008000997A1 (es) | 2007-04-08 | 2008-04-07 | Metodo de tratamiento que comprende administrar un agente farmaceutico activable con capacidad de efectuar un cambio celular al activarse, aplicar una energia iniciadora, donde el cambio celular trata el trastorno de proliferacion celular; metodo de |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2015000382A CL2015000382A1 (es) | 2007-04-08 | 2015-02-17 | Composición farmacéutica que comprende al menos un agente farmacéutico activable capaz de causar un cambio celular predeterminado y un aditivo con efecto terapéutico; uso para tratar un trastorno de proliferación celular tal como cancer. (divisional solicitud n° 997-2008). |
Country Status (12)
Country | Link |
---|---|
US (5) | US9358292B2 (es) |
EP (2) | EP2150549A4 (es) |
JP (1) | JP2010523690A (es) |
KR (6) | KR20200001607A (es) |
CN (2) | CN104027809B (es) |
AR (1) | AR066899A1 (es) |
AU (1) | AU2008237121B2 (es) |
CA (2) | CA2935870C (es) |
CL (3) | CL2008000997A1 (es) |
IN (2) | IN2015DN03080A (es) |
TW (2) | TWI654008B (es) |
WO (1) | WO2008124681A2 (es) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
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US9358292B2 (en) | 2007-04-08 | 2016-06-07 | Immunolight, Llc | Methods and systems for treating cell proliferation disorders |
US8376013B2 (en) | 2008-03-11 | 2013-02-19 | Duke University | Plasmonic assisted systems and methods for interior energy-activation from an exterior source |
US9488916B2 (en) * | 2007-04-08 | 2016-11-08 | Immunolight, Llc. | Interior energy-activation of photo-reactive species inside a medium or body |
US8383836B2 (en) * | 2009-04-21 | 2013-02-26 | Duke University | Methods and systems for treating cell proliferation disorders with psoralen derivatives |
US20090104212A1 (en) * | 2007-08-06 | 2009-04-23 | Immunolight | Methods and systems for treating cell proliferation disorders using two-photon simultaneous absorption |
TWI574712B (zh) | 2008-02-21 | 2017-03-21 | 伊穆諾萊特公司 | 利用電漿子增強之光譜療法(pepst)及激子-電漿增強之光療法(epep)治療細胞增生病症之組合物及產生自體疫苗之系統 |
WO2013009688A1 (en) | 2011-07-08 | 2013-01-17 | Bourke Frederic A | Phosphors and scintillators for light stimulation within a medium |
CN113274496A (zh) * | 2008-04-04 | 2021-08-20 | 免疫之光有限责任公司 | 用于原位光生物调节的非侵入性系统和方法 |
WO2010009106A1 (en) * | 2008-07-14 | 2010-01-21 | Bourke Frederic A Jr | Advanced methods and systems for treating cell proliferation disorders |
EP2403539A2 (en) * | 2009-03-02 | 2012-01-11 | Massachusetts Institute of Technology | Methods and systems for treatment and/or diagnosis |
JP5908396B2 (ja) | 2009-04-21 | 2016-04-26 | イミュノライト・エルエルシー | insituフォトバイオモジュレーションのための、非侵襲的エネルギーアップコンバージョン方法およびシステム |
WO2010144531A1 (en) * | 2009-06-09 | 2010-12-16 | Gary Wayne Jones | Method for selective photodynamic therapy and light source for implementation thereof |
WO2011011782A1 (en) * | 2009-07-24 | 2011-01-27 | Duke University | Functionalized metal-coated energy converting nanoparticles, methods for production thereof and methods for use |
WO2011060033A1 (en) * | 2009-11-10 | 2011-05-19 | Immunolight, L.L.C. | Up and down coversion systems for production of emitted light from various energy sources including radio frequency, microwave energy and magnetic induction sources for upconversion |
US9572880B2 (en) | 2010-08-27 | 2017-02-21 | Sienna Biopharmaceuticals, Inc. | Ultrasound delivery of nanoparticles |
ES2637373T3 (es) | 2010-08-27 | 2017-10-13 | Sienna Biopharmaceuticals, Inc. | Composiciones y métodos para la termomodulación dirigida |
CN103533934B (zh) * | 2011-03-17 | 2016-03-30 | 特尔汗什莫尔医学基础设施研究和服务公司 | 用于治疗自身免疫性疾病的喹诺酮类似物 |
WO2013006176A1 (en) * | 2011-07-07 | 2013-01-10 | Empire Technology Development Llc | Microwave induced photodynamic therapy |
CN108480620A (zh) | 2012-10-11 | 2018-09-04 | 纳诺康波西克斯公司 | 银纳米片组合物及方法 |
KR101536325B1 (ko) * | 2013-10-16 | 2015-07-14 | 주식회사 지니스 | 전자기파를 이용한 암 온열치료용 감작제 조성물 및 이를 이용한 암 치료 방법 |
CA2925698C (en) | 2013-11-28 | 2021-11-09 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Rna polymerase i inhibitors and uses thereof |
EP3097108B8 (en) * | 2014-01-23 | 2021-04-07 | Immunolight, LLC | Use of psoralen derivatives and combination therapy for treatment of cell proliferation disorders |
EP3838904A1 (en) * | 2014-06-19 | 2021-06-23 | Immunolight, LLC | Methods and systems for treating cell proliferation disorders with psoralen derivatives |
US11534622B2 (en) * | 2014-08-18 | 2022-12-27 | Immunolight, Llc | Non-invasive systems and methods for selective activation of photoreactive responses |
US20180071024A1 (en) * | 2015-03-20 | 2018-03-15 | Sienna Biopharmaceuticals, Inc. | Enhanced efficacy and targeted topical delivery of drugs to skin with nanoparticles |
WO2016154023A1 (en) * | 2015-03-20 | 2016-09-29 | The Regents Of The University Of Colorado, A Body Corporate | Novel light-activated compositions and methods using the same |
JP6824960B2 (ja) * | 2015-08-04 | 2021-02-03 | バキシオン セラピューティクス,リミテッド ライアビリティ カンパニー | 細菌由来ミニ細胞型バイオ医薬品の電離放射線照射滅菌およびその使用方法 |
US10407399B2 (en) | 2015-09-01 | 2019-09-10 | Howard Hughes Medical Institute | Ion-activated photolabile compounds |
KR102465104B1 (ko) * | 2016-04-25 | 2022-11-10 | 이뮤노라이트, 엘엘씨 | 삽입 디바이스들 및 매질 내부에 방출 광의 생산을 위한 시스템들 및 이들의 사용 방법들 |
AU2020233571A1 (en) | 2019-03-04 | 2021-11-04 | Immunolight, Llc | Energy augmentation structures for use with energy emitters and collectors |
CN110115761B (zh) * | 2019-05-09 | 2023-06-16 | 英诺激光科技股份有限公司 | 一种利用激光和载体技术制备疫苗的方法 |
EP4171635A4 (en) * | 2020-06-30 | 2024-08-07 | Univ Texas | RADIOSENSITIZATION OF CANCER BY IN SITU FORMATION OF GOLD NANOPARTICLES AND/OR GOLD NANOAGGREGATES |
WO2022072615A1 (en) * | 2020-09-30 | 2022-04-07 | Jernigan David A | Method of manipulating phages within the body to attack infectious target cells |
CN115414354A (zh) * | 2022-08-29 | 2022-12-02 | 西南医科大学 | 花椒毒素在制备治疗血小板减少症药物中的应用 |
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