BR9708468A - Tratamento de fotoferese de leucocitos. - Google Patents
Tratamento de fotoferese de leucocitos.Info
- Publication number
- BR9708468A BR9708468A BR9708468-9A BR9708468A BR9708468A BR 9708468 A BR9708468 A BR 9708468A BR 9708468 A BR9708468 A BR 9708468A BR 9708468 A BR9708468 A BR 9708468A
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- photopheresis
- leukocyte
- patient
- disclosed
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0066—Psoralene-activated UV-A photochemotherapy (PUVA-therapy), e.g. for treatment of psoriasis or eczema, extracorporeal photopheresis with psoralens or fucocoumarins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção: <B>"TRATAMENTO DE FOTOFERESE DE LEUCóCITOS"<D>. é revelado um processo para tratar infecções de células sang³íneas mononucleares, que não infecções retroviróticas. é também um processo para modular a função de monócitos. O processo envolve o tratamento do sangue do paciente com um composto fotoativável seguido por ativação de luz ultravioleta do composto fotoativável. O sangue tratado como tal é retornado para o paciente em um processo conhecido como fotoferese extracorpórea. A função do monócito é modulada por este tratamento.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1426996P | 1996-03-29 | 1996-03-29 | |
US2989396P | 1996-11-08 | 1996-11-08 | |
PCT/US1997/004772 WO1997036581A1 (en) | 1996-03-29 | 1997-03-26 | Photopheresis treatment of leukocytes |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9708468A true BR9708468A (pt) | 2000-01-04 |
Family
ID=26685876
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9708468-9A BR9708468A (pt) | 1996-03-29 | 1997-03-26 | Tratamento de fotoferese de leucocitos. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5984887A (pt) |
EP (1) | EP0935462B1 (pt) |
JP (1) | JP2000510101A (pt) |
CN (1) | CN1121217C (pt) |
AT (1) | ATE300298T1 (pt) |
AU (1) | AU710242B2 (pt) |
BR (1) | BR9708468A (pt) |
CA (1) | CA2250919C (pt) |
DE (1) | DE69733826T2 (pt) |
IL (1) | IL126366A (pt) |
WO (1) | WO1997036581A1 (pt) |
Families Citing this family (41)
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DE69734450T2 (de) * | 1996-03-29 | 2006-08-10 | Therakos, Inc. | Photopherese-behandlung von hcv-infektionen |
IL133913A0 (en) * | 1997-07-10 | 2001-04-30 | Therakos Inc | Treatment of inflammatory disorders of the bowel and urinary bladder |
EP1045846B1 (en) | 1997-11-28 | 2003-05-02 | Lg Chemical Limited | Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof |
US7611831B2 (en) | 1998-01-06 | 2009-11-03 | Cerus Corporation | Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix |
US6219584B1 (en) | 1999-07-09 | 2001-04-17 | Therakos, Inc. | Method and system for determining an effective amount of light energy to delivery to fluids having targets for the light energy |
US6495366B1 (en) * | 1999-09-03 | 2002-12-17 | Therakos, Inc. | Uninterrupted flow pump apparatus and method |
US8722422B2 (en) | 1999-09-03 | 2014-05-13 | Therakos, Inc. | Uninterrupted flow pump apparatus and method |
ATE285793T1 (de) * | 1999-10-05 | 2005-01-15 | Univ Montreal | Rhodaminderivate für die photodynamische diagnose und behandlung |
US6970740B2 (en) * | 2000-04-19 | 2005-11-29 | Clemson University | UVC rediation therapy for leukemia |
WO2001080939A2 (en) * | 2000-04-19 | 2001-11-01 | Clemson University | Uvc radiation therapy for chronic lymphocytic leukemia |
US6793643B1 (en) | 2000-04-21 | 2004-09-21 | Therakos, Inc. | Low extracorporeal volume treatment system |
US9044523B2 (en) | 2000-06-15 | 2015-06-02 | Terumo Bct, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
US20030139466A1 (en) * | 2001-11-29 | 2003-07-24 | Peritt David L. | Methods for pretreating a subject with extracorporeal photopheresis |
US7186230B2 (en) * | 2002-03-04 | 2007-03-06 | Therakos, Inc | Method and apparatus for the continuous separation of biological fluids into components |
US7479123B2 (en) * | 2002-03-04 | 2009-01-20 | Therakos, Inc. | Method for collecting a desired blood component and performing a photopheresis treatment |
US20040127840A1 (en) | 2002-03-04 | 2004-07-01 | Steve Gara | Blood separation apparatus and method of using the same |
CA2377442A1 (en) * | 2002-03-20 | 2003-09-20 | Thomas Ichim | Increasing tumor oxygen content by administration of stressed cells |
CN101351118B (zh) | 2005-11-02 | 2015-05-27 | 特拉科斯有限公司 | 凋亡细胞在离体产生调节t细胞中的应用 |
EP2021493A4 (en) | 2006-05-02 | 2010-04-14 | Therakos Inc | METHOD AND REAGENTS FOR DETECTING NECESSITY FOR TRANSPLANT-RECEPTACLE DISEASE OR TRANSPLANT-MORTALITY |
MX2008014111A (es) * | 2006-05-03 | 2009-03-06 | Therakos Inc | Metodos para tratar enfermedades qie implican enfermedades y condiciones relacionadas con estres. |
US8057418B2 (en) * | 2007-03-01 | 2011-11-15 | Nanospectra Biosciences, Inc. | Devices and methods for extracorporeal ablation of circulating cells |
US9358292B2 (en) | 2007-04-08 | 2016-06-07 | Immunolight, Llc | Methods and systems for treating cell proliferation disorders |
CA2720513C (en) | 2008-04-04 | 2018-09-25 | Immunolight, Llc | Non-invasive systems and methods for in-situ photobiomodulation |
US20100210989A1 (en) | 2008-12-23 | 2010-08-19 | Janet Lesley Macpherson | Processing blood |
US9399093B2 (en) | 2012-01-27 | 2016-07-26 | Fenwal, Inc. | Systems and methods for performing online extracorporeal photopheresis |
US20130252227A1 (en) | 2012-03-20 | 2013-09-26 | Fenwal, Inc. | Apparatus and Method for Providing Cryopreserved ECP-Treated Mononuclear Cells |
US11571504B2 (en) | 2019-03-21 | 2023-02-07 | Fenwal, Inc. | Apparatus and method for batch photoactivation of mononuclear cells |
WO2013181016A2 (en) * | 2012-05-27 | 2013-12-05 | Felder Mitchell S | Treatment for the rapid amelioration of clinical depression |
EP2953661B1 (en) | 2013-02-06 | 2018-10-17 | Fenwal, Inc. | Method for delivering desired light dose to cells in a light attenuating medium |
US10172995B2 (en) | 2013-02-06 | 2019-01-08 | Fenwal, Inc. | System and method for determining irradiation exposure time with irradiation sensors during extracorporeal photopheresis |
EP3097108B8 (en) | 2014-01-23 | 2021-04-07 | Immunolight, LLC | Use of psoralen derivatives and combination therapy for treatment of cell proliferation disorders |
US9208296B1 (en) | 2014-06-19 | 2015-12-08 | Norman Romanick | Prevention of use of a contaminated medical product |
EP3838904A1 (en) | 2014-06-19 | 2021-06-23 | Immunolight, LLC | Methods and systems for treating cell proliferation disorders with psoralen derivatives |
US10434240B2 (en) | 2015-08-17 | 2019-10-08 | Fenwal, Inc. | Methods and systems for processing and washing a photopheresis mononuclear cell product |
EP3372259B1 (en) | 2017-03-07 | 2022-11-23 | Fenwal, Inc. | System and methods for separating blood under conditions of reduced plasma clarity |
US20190099610A1 (en) * | 2017-10-04 | 2019-04-04 | Hyper Light Technologies, Llc | Cancer cell treatment |
US11318239B2 (en) | 2018-03-01 | 2022-05-03 | Fenwal, Inc. | Systems and methods for performing online extracorporeal photopheresis |
WO2019217964A1 (en) | 2018-05-11 | 2019-11-14 | Lupagen, Inc. | Systems and methods for closed loop, real-time modifications of patient cells |
EP4077639B1 (en) | 2019-12-20 | 2024-06-12 | Mallinckrodt Pharmaceuticals Ireland Limited | Method for generating immunoregulatory cells in a blood-derived sample |
WO2024134596A1 (en) | 2022-12-21 | 2024-06-27 | Mallinckrodt Pharmaceuticals Ireland Limited | Adiponectin alone or in combination with extracorporeal photopheresis (ecp) for immune related adverse events of immune checkpoint inhibitors |
EP4389122A1 (en) | 2022-12-21 | 2024-06-26 | Mallinckrodt Pharmaceuticals Ireland Limited | Adiponectin alone or in combination with extracorporeal photopheresis (ecp) for immune related adverse events of immune checkpoint inhibitors |
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US299953A (en) | 1884-06-10 | Ealph bbownson | ||
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FR2521999B1 (fr) * | 1982-02-25 | 1984-05-25 | Inst Nat Sante Rech Med | Pyrido (3',4' : 4,5) furo (3,2-g) coumarines ou pyrido (3,4-h) psoralenes, obtention, applications en cosmetologie et a titre de medicaments, et compositions cosmetiques et pharmaceutiques les contenant |
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DE69734450T2 (de) * | 1996-03-29 | 2006-08-10 | Therakos, Inc. | Photopherese-behandlung von hcv-infektionen |
AU2453697A (en) * | 1996-04-10 | 1997-10-29 | Trustees Of The University Of Pennsylvania, The | Use of photopheresis in the treatment of chronic infection by hepatitis c virus |
-
1997
- 1997-03-26 WO PCT/US1997/004772 patent/WO1997036581A1/en active IP Right Grant
- 1997-03-26 BR BR9708468-9A patent/BR9708468A/pt not_active Application Discontinuation
- 1997-03-26 EP EP97919906A patent/EP0935462B1/en not_active Expired - Lifetime
- 1997-03-26 US US08/832,322 patent/US5984887A/en not_active Expired - Lifetime
- 1997-03-26 AU AU24228/97A patent/AU710242B2/en not_active Ceased
- 1997-03-26 CN CN97193295A patent/CN1121217C/zh not_active Expired - Fee Related
- 1997-03-26 DE DE69733826T patent/DE69733826T2/de not_active Expired - Lifetime
- 1997-03-26 CA CA002250919A patent/CA2250919C/en not_active Expired - Fee Related
- 1997-03-26 IL IL126366A patent/IL126366A/en not_active IP Right Cessation
- 1997-03-26 JP JP09535364A patent/JP2000510101A/ja active Pending
- 1997-03-26 AT AT97919906T patent/ATE300298T1/de active
Also Published As
Publication number | Publication date |
---|---|
DE69733826T2 (de) | 2006-05-24 |
CN1121217C (zh) | 2003-09-17 |
CA2250919A1 (en) | 1997-10-09 |
AU710242B2 (en) | 1999-09-16 |
IL126366A0 (en) | 1999-05-09 |
AU2422897A (en) | 1997-10-22 |
JP2000510101A (ja) | 2000-08-08 |
IL126366A (en) | 2011-10-31 |
CN1214630A (zh) | 1999-04-21 |
EP0935462A4 (en) | 2001-04-18 |
WO1997036581A1 (en) | 1997-10-09 |
DE69733826D1 (de) | 2005-09-01 |
CA2250919C (en) | 2008-05-13 |
US5984887A (en) | 1999-11-16 |
ATE300298T1 (de) | 2005-08-15 |
EP0935462B1 (en) | 2005-07-27 |
EP0935462A1 (en) | 1999-08-18 |
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