CL2014002471A1 - Uso de un derivado de pirazol en el tratamiento de las exacerbaciones agudas de la enfermedad pulmonar obstructiva crónica. - Google Patents
Uso de un derivado de pirazol en el tratamiento de las exacerbaciones agudas de la enfermedad pulmonar obstructiva crónica.Info
- Publication number
- CL2014002471A1 CL2014002471A1 CL2014002471A CL2014002471A CL2014002471A1 CL 2014002471 A1 CL2014002471 A1 CL 2014002471A1 CL 2014002471 A CL2014002471 A CL 2014002471A CL 2014002471 A CL2014002471 A CL 2014002471A CL 2014002471 A1 CL2014002471 A1 CL 2014002471A1
- Authority
- CL
- Chile
- Prior art keywords
- treatment
- pulmonary disease
- chronic obstructive
- obstructive pulmonary
- pyrazole derivative
- Prior art date
Links
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 title 1
- 230000009798 acute exacerbation Effects 0.000 title 1
- 150000003217 pyrazoles Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261613187P | 2012-03-20 | 2012-03-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2014002471A1 true CL2014002471A1 (es) | 2015-01-09 |
Family
ID=47901996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2014002471A CL2014002471A1 (es) | 2012-03-20 | 2014-09-17 | Uso de un derivado de pirazol en el tratamiento de las exacerbaciones agudas de la enfermedad pulmonar obstructiva crónica. |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US9339491B2 (https=) |
| EP (1) | EP2827860B1 (https=) |
| JP (1) | JP6091593B2 (https=) |
| KR (1) | KR101793777B1 (https=) |
| CN (1) | CN104203234B (https=) |
| AU (1) | AU2013237503B2 (https=) |
| BR (1) | BR112014023107B1 (https=) |
| CA (1) | CA2866108C (https=) |
| CL (1) | CL2014002471A1 (https=) |
| CY (1) | CY1118327T1 (https=) |
| DK (1) | DK2827860T3 (https=) |
| ES (1) | ES2605942T3 (https=) |
| HR (1) | HRP20161514T1 (https=) |
| HU (1) | HUE032004T2 (https=) |
| IL (1) | IL234537A (https=) |
| LT (1) | LT2827860T (https=) |
| MA (1) | MA37455B1 (https=) |
| MX (1) | MX351996B (https=) |
| NZ (1) | NZ628392A (https=) |
| PH (1) | PH12014502107B1 (https=) |
| PL (1) | PL2827860T3 (https=) |
| PT (1) | PT2827860T (https=) |
| RU (1) | RU2625762C2 (https=) |
| SG (1) | SG11201404941WA (https=) |
| SI (1) | SI2827860T1 (https=) |
| TN (1) | TN2014000350A1 (https=) |
| TW (1) | TWI583381B (https=) |
| WO (1) | WO2013139809A1 (https=) |
| ZA (1) | ZA201405871B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2600833C1 (ru) * | 2015-09-03 | 2016-10-27 | ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ "РОССИЙСКИЙ НАУЧНЫЙ ЦЕНТР РАДИОЛОГИИ И ХИРУРГИЧЕСКИХ ТЕХНОЛОГИЙ" МИНИСТЕРСТВА ЗДРАВООХРАНЕНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ (ФГБУ "РНЦРХТ" Минздрава России) | Способ лечения хронической обструктивной болезни легких |
| RU2600822C1 (ru) * | 2015-09-03 | 2016-10-27 | ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ "РОССИЙСКИЙ НАУЧНЫЙ ЦЕНТР РАДИОЛОГИИ И ХИРУРГИЧЕСКИХ ТЕХНОЛОГИЙ" МИНИСТЕРСТВА ЗДРАВООХРАНЕНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ (ФГБУ "РНЦРХТ" Минздрава России) | Способ лечения хронического обструктивного бронхита |
| KR102762199B1 (ko) * | 2016-03-08 | 2025-02-07 | 메레오 바이오파마 1 리미티드 | 만성 폐쇄성 폐 질환의 급성 악화 치료를 위한 투약법 |
| BR112018067784A2 (pt) * | 2016-03-08 | 2019-01-15 | Mereo Biopharma 1 Ltd | regime de dosagem para o tratamento de exacerbações agudas de condições inflamatórias |
| US10331542B2 (en) * | 2016-06-23 | 2019-06-25 | International Business Machines Corporation | System and method for detecting and alerting unexpected behavior of software applications |
| GB201612238D0 (en) * | 2016-07-14 | 2016-08-31 | Mereo Biopharma 1 Ltd | Method for producing a polymorphic form of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-Yl]-n-cyclopropyl-4-methylbenzamide |
| GB201612240D0 (en) | 2016-07-14 | 2016-08-31 | Mereo Biopharma 1 Ltd | Method for producing a polymorphic form of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide |
| BR112020006677A2 (pt) | 2017-10-05 | 2020-10-06 | Fulcrum Therapeutics, Inc. | uso de inibidores p38 para reduzir a expressão de dux4 |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
| JP7280627B2 (ja) * | 2017-12-11 | 2023-05-24 | メレオ バイオファーマ １ リミテッド | 慢性閉塞性肺疾患の急性増悪の処置における３－［５－アミノ－４－（３－シアノベンゾイル）－ピラゾール－１－イル］－ｎ－シクロプロピル－４－メチルベンズアミドの使用 |
| AU2018381874B2 (en) | 2017-12-11 | 2024-08-15 | Mereo Biopharma 1 Limited | Use of 3-(5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl)-N-cyclopropyl-4-methylbenzamide in the prevention or reduction of acute exacerbations of chronic obstructive pulmonary disease |
| CN114141383A (zh) * | 2021-12-17 | 2022-03-04 | 湖南大学 | 慢阻肺智能护理方法、装置及系统 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2298743T3 (pl) | 2003-06-26 | 2013-02-28 | Novartis Ag | Inhibitory kinaz P38 na bazie 5-członowych heterocykli |
| GB0603684D0 (en) * | 2006-02-23 | 2006-04-05 | Novartis Ag | Organic compounds |
-
2013
- 2013-03-19 WO PCT/EP2013/055730 patent/WO2013139809A1/en not_active Ceased
- 2013-03-19 HU HUE13710851A patent/HUE032004T2/en unknown
- 2013-03-19 DK DK13710851.0T patent/DK2827860T3/en active
- 2013-03-19 MA MA37455A patent/MA37455B1/fr unknown
- 2013-03-19 SI SI201330397A patent/SI2827860T1/sl unknown
- 2013-03-19 AU AU2013237503A patent/AU2013237503B2/en active Active
- 2013-03-19 PL PL13710851T patent/PL2827860T3/pl unknown
- 2013-03-19 BR BR112014023107-9A patent/BR112014023107B1/pt active IP Right Grant
- 2013-03-19 JP JP2015500892A patent/JP6091593B2/ja active Active
- 2013-03-19 ES ES13710851.0T patent/ES2605942T3/es active Active
- 2013-03-19 KR KR1020147025904A patent/KR101793777B1/ko active Active
- 2013-03-19 EP EP13710851.0A patent/EP2827860B1/en active Active
- 2013-03-19 MX MX2014011291A patent/MX351996B/es active IP Right Grant
- 2013-03-19 NZ NZ628392A patent/NZ628392A/en unknown
- 2013-03-19 CA CA2866108A patent/CA2866108C/en active Active
- 2013-03-19 CN CN201380015703.5A patent/CN104203234B/zh active Active
- 2013-03-19 SG SG11201404941WA patent/SG11201404941WA/en unknown
- 2013-03-19 LT LTEP13710851.0T patent/LT2827860T/lt unknown
- 2013-03-19 US US14/386,174 patent/US9339491B2/en active Active
- 2013-03-19 PT PT137108510T patent/PT2827860T/pt unknown
- 2013-03-19 TW TW102109739A patent/TWI583381B/zh active
- 2013-03-19 RU RU2014141893A patent/RU2625762C2/ru active
- 2013-03-19 HR HRP20161514TT patent/HRP20161514T1/hr unknown
-
2014
- 2014-08-11 ZA ZA2014/05871A patent/ZA201405871B/en unknown
- 2014-08-11 TN TNP2014000350A patent/TN2014000350A1/fr unknown
- 2014-09-08 IL IL234537A patent/IL234537A/en active IP Right Grant
- 2014-09-17 CL CL2014002471A patent/CL2014002471A1/es unknown
- 2014-09-22 PH PH12014502107A patent/PH12014502107B1/en unknown
-
2016
- 2016-04-29 US US15/143,356 patent/US20160243081A1/en not_active Abandoned
- 2016-11-18 CY CY20161101194T patent/CY1118327T1/el unknown
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