CL2008003832A1 - Compuestos derivados del acido 2-(4-(2-(((2-cloro-fenil)sulfonil)metil)-4-(carbamoil)fenoxi)-2-fluorofenil) acetico, forma cristalina anhidra ll de un compuesto especifico; procesos de preparacion; compuestos intermediario, composicion farmaceutica; y uso en el tratamiento de enfermedades inflamatorias, tales como epoc, rinitis, asma y la dermatitis. - Google Patents

Compuestos derivados del acido 2-(4-(2-(((2-cloro-fenil)sulfonil)metil)-4-(carbamoil)fenoxi)-2-fluorofenil) acetico, forma cristalina anhidra ll de un compuesto especifico; procesos de preparacion; compuestos intermediario, composicion farmaceutica; y uso en el tratamiento de enfermedades inflamatorias, tales como epoc, rinitis, asma y la dermatitis.

Info

Publication number
CL2008003832A1
CL2008003832A1 CL2008003832A CL2008003832A CL2008003832A1 CL 2008003832 A1 CL2008003832 A1 CL 2008003832A1 CL 2008003832 A CL2008003832 A CL 2008003832A CL 2008003832 A CL2008003832 A CL 2008003832A CL 2008003832 A1 CL2008003832 A1 CL 2008003832A1
Authority
CL
Chile
Prior art keywords
copd
rhinitis
dermatitis
pharmaceutical composition
acetic acid
Prior art date
Application number
CL2008003832A
Other languages
English (en)
Spanish (es)
Inventor
Liu Jiwen
C Medina Julio
Grillo Mark
Li An-Rong
Su Yongli
Wang Yingcai
Jona Janan
Allgeier Alan
Milne Jacqueline
m Jerry
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of CL2008003832A1 publication Critical patent/CL2008003832A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CL2008003832A 2007-12-19 2008-12-19 Compuestos derivados del acido 2-(4-(2-(((2-cloro-fenil)sulfonil)metil)-4-(carbamoil)fenoxi)-2-fluorofenil) acetico, forma cristalina anhidra ll de un compuesto especifico; procesos de preparacion; compuestos intermediario, composicion farmaceutica; y uso en el tratamiento de enfermedades inflamatorias, tales como epoc, rinitis, asma y la dermatitis. CL2008003832A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US843307P 2007-12-19 2007-12-19

Publications (1)

Publication Number Publication Date
CL2008003832A1 true CL2008003832A1 (es) 2010-03-26

Family

ID=40564868

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008003832A CL2008003832A1 (es) 2007-12-19 2008-12-19 Compuestos derivados del acido 2-(4-(2-(((2-cloro-fenil)sulfonil)metil)-4-(carbamoil)fenoxi)-2-fluorofenil) acetico, forma cristalina anhidra ll de un compuesto especifico; procesos de preparacion; compuestos intermediario, composicion farmaceutica; y uso en el tratamiento de enfermedades inflamatorias, tales como epoc, rinitis, asma y la dermatitis.

Country Status (20)

Country Link
US (1) US8183293B2 (enExample)
EP (1) EP2231595B1 (enExample)
JP (1) JP5437267B2 (enExample)
KR (1) KR20100102668A (enExample)
CN (1) CN101903338A (enExample)
AR (1) AR071279A1 (enExample)
AU (1) AU2008343924B2 (enExample)
BR (1) BRPI0821197A2 (enExample)
CA (1) CA2707789A1 (enExample)
CL (1) CL2008003832A1 (enExample)
CO (1) CO6321234A2 (enExample)
CR (1) CR11572A (enExample)
EA (1) EA201001029A1 (enExample)
ES (1) ES2471919T3 (enExample)
IL (1) IL206069A0 (enExample)
MA (1) MA32013B1 (enExample)
PE (1) PE20091526A1 (enExample)
TN (1) TN2010000223A1 (enExample)
TW (1) TW200940051A (enExample)
WO (1) WO2009085177A1 (enExample)

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KR20140113667A (ko) 2011-12-16 2014-09-24 아토픽스 테라퓨릭스 리미티드 호산구성 식도염의 치료를 위한 ｃｒｔｈ2 길항제 및 양성자 펌프 저해제의 조합
US9974759B2 (en) * 2013-05-31 2018-05-22 Indiana University Research And Technology Corporation Beta 2 adrenoceptor antagonists for treating orthostatic hypotension
WO2016128565A1 (en) * 2015-02-13 2016-08-18 Institut National De La Sante Et De La Recherche Medicale (Inserm) Ptgdr-1 and/or ptgdr-2 antagonists for preventing and/or treating systemic lupus erythematosus
GEAP202014908A (en) 2016-03-22 2020-03-10 Merck Sharp & Dohme Allosteric modulators of nicotinic acetylcholine receptors
EP3424927B1 (en) * 2017-07-04 2019-04-17 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Efficient process for the preparation of sitagliptin through a very effective preparation of the intermediate 2,4,5-trifluorophenylacetic acid

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Also Published As

Publication number Publication date
US20090275659A1 (en) 2009-11-05
BRPI0821197A2 (pt) 2015-06-16
EP2231595B1 (en) 2014-04-23
AU2008343924B2 (en) 2013-01-17
JP2011507847A (ja) 2011-03-10
CR11572A (es) 2010-08-13
CN101903338A (zh) 2010-12-01
US8183293B2 (en) 2012-05-22
WO2009085177A1 (en) 2009-07-09
CO6321234A2 (es) 2011-09-20
CA2707789A1 (en) 2009-07-09
AU2008343924A1 (en) 2009-07-09
AR071279A1 (es) 2010-06-09
MA32013B1 (fr) 2011-01-03
IL206069A0 (en) 2010-11-30
EA201001029A1 (ru) 2011-06-30
EP2231595A1 (en) 2010-09-29
TW200940051A (en) 2009-10-01
TN2010000223A1 (en) 2011-11-11
JP5437267B2 (ja) 2014-03-12
ES2471919T3 (es) 2014-06-27
PE20091526A1 (es) 2009-11-01
KR20100102668A (ko) 2010-09-24
AU2008343924A2 (en) 2011-02-17

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