CL2008002952A1 - Proteina de union a antigenos que se une a interleucina-23 humana (il-23); composicion farmaceutica que la comprende; y su uso para tratar inflamaciones mediadas por el sistema inmunitario - Google Patents
Proteina de union a antigenos que se une a interleucina-23 humana (il-23); composicion farmaceutica que la comprende; y su uso para tratar inflamaciones mediadas por el sistema inmunitarioInfo
- Publication number
- CL2008002952A1 CL2008002952A1 CL2008002952A CL2008002952A CL2008002952A1 CL 2008002952 A1 CL2008002952 A1 CL 2008002952A1 CL 2008002952 A CL2008002952 A CL 2008002952A CL 2008002952 A CL2008002952 A CL 2008002952A CL 2008002952 A1 CL2008002952 A1 CL 2008002952A1
- Authority
- CL
- Chile
- Prior art keywords
- antigen
- pharmaceutical composition
- binding protein
- binds human
- human interleukin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Proteína de unión a antígenos que se une a interleucina-23 humana (il-23); composición farmacéutica que la comprende; y su uso para tratar inflamaciones mediadas por el sistema inmunitario.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US97784107P | 2007-10-05 | 2007-10-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2008002952A1 true CL2008002952A1 (es) | 2009-10-16 |
Family
ID=40378889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008002952A CL2008002952A1 (es) | 2007-10-05 | 2008-10-03 | Proteina de union a antigenos que se une a interleucina-23 humana (il-23); composicion farmaceutica que la comprende; y su uso para tratar inflamaciones mediadas por el sistema inmunitario |
Country Status (16)
Country | Link |
---|---|
US (2) | US20110206686A1 (es) |
EP (1) | EP2205637A1 (es) |
JP (1) | JP2011501738A (es) |
KR (1) | KR20100097654A (es) |
CN (1) | CN101889026A (es) |
AR (1) | AR068723A1 (es) |
AU (1) | AU2008306850A1 (es) |
BR (1) | BRPI0818620A2 (es) |
CA (1) | CA2700758A1 (es) |
CL (1) | CL2008002952A1 (es) |
EA (1) | EA201000424A1 (es) |
MX (1) | MX2010003574A (es) |
PE (1) | PE20091342A1 (es) |
TW (1) | TW200930729A (es) |
WO (1) | WO2009043933A1 (es) |
ZA (1) | ZA201002275B (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103396489A (zh) | 2007-02-23 | 2013-11-20 | 默沙东公司 | 工程改造的抗IL-23p19抗体 |
HUE042172T2 (hu) | 2007-02-23 | 2019-06-28 | Merck Sharp & Dohme | Genetikailag elõállított anti-il-23P19 antitestek |
BR122021026834B1 (pt) | 2008-04-25 | 2022-11-08 | Takeda Pharmaceutical Company Limited | Anticorpos isolados que se ligam a fcrn, composição farmacêutica que compreende os mesmos e métodos para detectar e para modular fcrn |
US8263748B2 (en) | 2008-08-27 | 2012-09-11 | Schering Corporation | Lyophilized formulations of engineered anti-IL-23p19 antibodies |
EP2414393A1 (en) * | 2009-04-01 | 2012-02-08 | Glaxo Group Limited | Anti-il-23 immunoglobulins |
EP2480251A1 (en) | 2009-09-21 | 2012-08-01 | Peptinov SAS | Carrier conjugates of il-23-peptides and their induced antibodies |
JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
CN103282382B (zh) | 2010-11-04 | 2017-11-03 | 勃林格殷格翰国际有限公司 | 抗il‑23抗体 |
AU2012262007B2 (en) | 2011-06-02 | 2017-06-22 | Takeda Pharmaceutical Company Limited | Fc receptor binding proteins |
KR102124758B1 (ko) | 2012-05-03 | 2020-06-19 | 베링거 인겔하임 인터내셔날 게엠베하 | 항-il-23p19 항체 |
EP2866833B1 (en) | 2012-06-27 | 2019-05-15 | Merck Sharp & Dohme Corp. | Crystalline anti-human il-23 antibodies |
EP2920202B1 (en) | 2012-11-19 | 2018-08-29 | Pieris Pharmaceuticals GmbH | Novel specific-binding polypeptides and uses thereof |
UA117466C2 (uk) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
US9708404B2 (en) | 2012-12-21 | 2017-07-18 | Seattle Genetics, Inc. | Anti-NTB-A antibodies and related compositions and methods |
CN105307675A (zh) | 2013-03-15 | 2016-02-03 | 美国安进公司 | 使用抗il23抗体治疗克罗恩氏病的方法 |
JP2016517408A (ja) | 2013-03-15 | 2016-06-16 | アムジェン インコーポレイテッド | 抗il−23抗体を用いた乾癬の治療方法 |
EP3789397B1 (en) | 2014-05-22 | 2023-12-06 | Pieris Pharmaceuticals GmbH | Novel specific-binding polypeptides and uses thereof |
JP2017524359A (ja) | 2014-07-24 | 2017-08-31 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Il−23a関連疾患の処置に有用なバイオマーカー |
EA202193002A2 (ru) | 2014-09-03 | 2022-03-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Соединение, нацеленное на ил-23a и фно-альфа, и его применение |
RU2018113694A (ru) | 2015-09-17 | 2019-10-17 | Эмджен Инк. | Прогноз клинического ответа на антагонисты ил-23 с использованием биомаркеров сигнального пути ил-23 |
KR20180072819A (ko) | 2015-10-30 | 2018-06-29 | 아블린쓰 엔.브이. | Il-23에 대한 폴리펩티드 |
CN109154611B (zh) | 2015-12-09 | 2022-04-08 | 科尔沃斯制药股份有限公司 | 人源化抗cd73抗体 |
CN108472367A (zh) | 2015-12-22 | 2018-08-31 | 美国安进公司 | 作为对il23拮抗剂的临床应答的预测因子的ccl20 |
RU2019138507A (ru) | 2017-05-02 | 2021-06-02 | Мерк Шарп И Доум Корп. | Составы антител против lag3 и совместные составы антител против lag3 и антител против pd-1 |
JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
AU2019300491A1 (en) | 2018-07-13 | 2021-03-04 | Astrazeneca Collaboration Ventures, Llc | Treating ulcerative colitis with brazikumab |
JP2022551603A (ja) | 2019-10-03 | 2022-12-12 | エータイアー ファーマ, インコーポレイテッド | 抗nrp2抗体を含む組成物および方法 |
JP2023509373A (ja) | 2019-12-20 | 2023-03-08 | ノヴァロック バイオセラピューティクス, リミテッド | 抗インターロイキン-23 p19抗体およびそれの使用方法 |
CN113698480B (zh) * | 2021-09-18 | 2022-07-01 | 东大生物技术(苏州)有限公司 | 一组il-23单克隆抗体及其医药用途 |
WO2023076998A1 (en) * | 2021-10-27 | 2023-05-04 | Atyr Pharma, Inc. | COMPOSITIONS AND METHODS COMPRISING ANTI-NRP2a ANTIBODIES |
CN114920830B (zh) * | 2022-05-07 | 2023-05-16 | 北京大学 | Vκ4-1-IgLC多肽及其用途 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1759123B (zh) * | 2003-03-10 | 2011-04-13 | 先灵公司 | Il-23激动剂及拮抗剂的用途;相关试剂 |
EP1896073B1 (en) * | 2005-06-30 | 2013-03-06 | Janssen Biotech, Inc. | Anti-il-23 antibodies, compositions, methods and uses |
MX2008002179A (es) * | 2005-08-25 | 2008-04-22 | Lilly Co Eli | Anticuerpos anti-il-23. |
ES2619845T3 (es) * | 2005-08-31 | 2017-06-27 | Merck Sharp & Dohme Corp. | Anticuerpos anti-IL-23 diseñados por ingeniería genética |
-
2008
- 2008-10-02 AR ARP080104318A patent/AR068723A1/es not_active Application Discontinuation
- 2008-10-03 TW TW097138322A patent/TW200930729A/zh unknown
- 2008-10-03 PE PE2008001726A patent/PE20091342A1/es not_active Application Discontinuation
- 2008-10-03 WO PCT/EP2008/063289 patent/WO2009043933A1/en active Application Filing
- 2008-10-03 KR KR1020107010032A patent/KR20100097654A/ko not_active Application Discontinuation
- 2008-10-03 CL CL2008002952A patent/CL2008002952A1/es unknown
- 2008-10-03 BR BRPI0818620A patent/BRPI0818620A2/pt not_active IP Right Cessation
- 2008-10-03 EA EA201000424A patent/EA201000424A1/ru unknown
- 2008-10-03 CA CA2700758A patent/CA2700758A1/en not_active Abandoned
- 2008-10-03 CN CN2008801191723A patent/CN101889026A/zh active Pending
- 2008-10-03 US US12/681,413 patent/US20110206686A1/en not_active Abandoned
- 2008-10-03 JP JP2010527465A patent/JP2011501738A/ja active Pending
- 2008-10-03 US US12/245,426 patent/US20090123479A1/en not_active Abandoned
- 2008-10-03 EP EP08836275A patent/EP2205637A1/en not_active Withdrawn
- 2008-10-03 MX MX2010003574A patent/MX2010003574A/es not_active Application Discontinuation
- 2008-10-03 AU AU2008306850A patent/AU2008306850A1/en not_active Abandoned
-
2010
- 2010-03-30 ZA ZA2010/02275A patent/ZA201002275B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EA201000424A1 (ru) | 2010-10-29 |
MX2010003574A (es) | 2010-04-22 |
JP2011501738A (ja) | 2011-01-13 |
AR068723A1 (es) | 2009-12-02 |
US20090123479A1 (en) | 2009-05-14 |
ZA201002275B (en) | 2011-06-29 |
US20110206686A1 (en) | 2011-08-25 |
EP2205637A1 (en) | 2010-07-14 |
AU2008306850A1 (en) | 2009-04-09 |
CN101889026A (zh) | 2010-11-17 |
CA2700758A1 (en) | 2009-04-09 |
WO2009043933A1 (en) | 2009-04-09 |
PE20091342A1 (es) | 2009-09-16 |
BRPI0818620A2 (pt) | 2019-09-24 |
TW200930729A (en) | 2009-07-16 |
KR20100097654A (ko) | 2010-09-03 |
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