CL2008001814A1 - Anticuerpos anti-factor de crecimiento 1 y 2 semejantes a insulina (igf-1, igf-2); molecula de adn que los codifica; vector y celula huesped; metodo de produccion; composicion farmaceutica que los comprende; y su uso para tratar cancer. - Google Patents
Anticuerpos anti-factor de crecimiento 1 y 2 semejantes a insulina (igf-1, igf-2); molecula de adn que los codifica; vector y celula huesped; metodo de produccion; composicion farmaceutica que los comprende; y su uso para tratar cancer.Info
- Publication number
- CL2008001814A1 CL2008001814A1 CL2008001814A CL2008001814A CL2008001814A1 CL 2008001814 A1 CL2008001814 A1 CL 2008001814A1 CL 2008001814 A CL2008001814 A CL 2008001814A CL 2008001814 A CL2008001814 A CL 2008001814A CL 2008001814 A1 CL2008001814 A1 CL 2008001814A1
- Authority
- CL
- Chile
- Prior art keywords
- igf
- insulin
- encodes
- antibodies
- vector
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Abstract
Anticuerpos anti-factor de crecimiento 1 y 2 semejantes a insulina (igf-1, igf-2); molécula de ADN que los codifica; vector y célula huésped; método de producción; composición farmacéutica que los comprende; y su uso para tratar cáncer.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07110587 | 2007-06-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2008001814A1 true CL2008001814A1 (es) | 2009-09-11 |
Family
ID=39154657
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008001814A CL2008001814A1 (es) | 2007-06-19 | 2008-06-18 | Anticuerpos anti-factor de crecimiento 1 y 2 semejantes a insulina (igf-1, igf-2); molecula de adn que los codifica; vector y celula huesped; metodo de produccion; composicion farmaceutica que los comprende; y su uso para tratar cancer. |
Country Status (10)
Country | Link |
---|---|
US (1) | US8580254B2 (es) |
EP (1) | EP2220119B1 (es) |
JP (1) | JP2010531140A (es) |
AR (1) | AR067046A1 (es) |
CA (1) | CA2689521A1 (es) |
CL (1) | CL2008001814A1 (es) |
PE (1) | PE20090368A1 (es) |
TW (1) | TW200909446A (es) |
UY (1) | UY31160A1 (es) |
WO (1) | WO2008155387A2 (es) |
Families Citing this family (26)
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EP1797881B1 (en) | 2004-09-17 | 2009-04-15 | Eisai R&D Management Co., Ltd. | Medicinal composition with improved stability and reduced gelation properties |
EP2281901B1 (en) * | 2005-08-02 | 2013-11-27 | Eisai R&D Management Co., Ltd. | Anti-tumour pharmaceutical composition with angiogenesis inhibitors |
EP2036557B1 (en) | 2006-05-18 | 2015-10-21 | Eisai R&D Management Co., Ltd. | Antitumor agent for thyroid cancer |
PE20090368A1 (es) | 2007-06-19 | 2009-04-28 | Boehringer Ingelheim Int | Anticuerpos anti-igf |
US8952035B2 (en) * | 2007-11-09 | 2015-02-10 | Eisai R&D Management Co., Ltd. | Combination of anti-angiogenic substance and anti-tumor platinum complex |
UY32317A (es) | 2008-12-12 | 2010-07-30 | Boehringer Ingelheim Int | Anticuerpos anti-igf |
JP2012518657A (ja) * | 2009-02-25 | 2012-08-16 | オーエスアイ・ファーマシューティカルズ,エルエルシー | 併用抗癌治療 |
TW201102068A (en) * | 2009-06-02 | 2011-01-16 | Novartis Ag | Treatment of ophthalmologic disorders mediated by alpha-carbonic anhydrase isoforms |
EP2486055A4 (en) * | 2009-10-07 | 2013-04-17 | Us Health | HUMAN DOMAIN ANTIBODIES AGAINST COMPONENTS OF THE HUMAN INSULIN TYPE (IGF) GROWTH FACTOR SYSTEM |
AU2014256364B2 (en) * | 2009-10-07 | 2016-07-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Human domain antibodies against components of the human insulin-like growth factor (IGF) system |
EP2719708B1 (en) * | 2009-11-13 | 2017-10-25 | Daiichi Sankyo Europe GmbH | Material and methods for treating or preventing HER-3 associated diseases |
EP2382976A1 (en) | 2010-04-30 | 2011-11-02 | Hiroshima University | Use of pdgf-r inhibitors for the treatment of lymph node metastasis of gastric cancer |
CN102958523B (zh) * | 2010-06-25 | 2014-11-19 | 卫材R&D管理有限公司 | 使用具有激酶抑制作用的组合的抗肿瘤剂 |
WO2012144463A1 (ja) | 2011-04-18 | 2012-10-26 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 腫瘍治療剤 |
US9945862B2 (en) | 2011-06-03 | 2018-04-17 | Eisai R&D Management Co., Ltd. | Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds |
BR112015009004A8 (pt) | 2012-12-21 | 2021-07-20 | Eisai R&D Man Co Ltd | forma amorfa de derivado de quinolina e método de produção da mesma |
US20140255413A1 (en) | 2013-03-07 | 2014-09-11 | Boehringer Ingelheim International Gmbh | Combination therapy for neoplasia treatment |
MX368099B (es) | 2013-05-14 | 2019-09-19 | Eisai R&D Man Co Ltd | Biomarcadores para predecir y evaluar el grado de respuesta de sujetos con cancer de endometrio a compuestos de tipo lenvatinib. |
US20140378401A1 (en) * | 2013-06-21 | 2014-12-25 | Gnt, Llc | Ophthalmic Lipophilic and Hydrophilic Drug Delivery Vehicle Formulations |
US20150209426A1 (en) * | 2014-01-24 | 2015-07-30 | Boehringer Ingelheim International Gmbh | Treatment of cancer |
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-
2008
- 2008-06-17 PE PE2008001030A patent/PE20090368A1/es not_active Application Discontinuation
- 2008-06-18 AR ARP080102595A patent/AR067046A1/es unknown
- 2008-06-18 CL CL2008001814A patent/CL2008001814A1/es unknown
- 2008-06-18 TW TW097122727A patent/TW200909446A/zh unknown
- 2008-06-18 UY UY31160A patent/UY31160A1/es not_active Application Discontinuation
- 2008-06-19 US US12/665,373 patent/US8580254B2/en active Active
- 2008-06-19 JP JP2010512689A patent/JP2010531140A/ja active Pending
- 2008-06-19 WO PCT/EP2008/057789 patent/WO2008155387A2/en active Application Filing
- 2008-06-19 EP EP08761223.0A patent/EP2220119B1/en not_active Not-in-force
- 2008-06-19 CA CA002689521A patent/CA2689521A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2008155387A3 (en) | 2009-04-30 |
PE20090368A1 (es) | 2009-04-28 |
UY31160A1 (es) | 2009-01-30 |
US8580254B2 (en) | 2013-11-12 |
CA2689521A1 (en) | 2008-12-24 |
AR067046A1 (es) | 2009-09-30 |
US20100196395A1 (en) | 2010-08-05 |
WO2008155387A2 (en) | 2008-12-24 |
TW200909446A (en) | 2009-03-01 |
EP2220119B1 (en) | 2013-08-14 |
JP2010531140A (ja) | 2010-09-24 |
EP2220119A2 (en) | 2010-08-25 |
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