CH672792A5 - - Google Patents
Download PDFInfo
- Publication number
- CH672792A5 CH672792A5 CH537/86A CH53786A CH672792A5 CH 672792 A5 CH672792 A5 CH 672792A5 CH 537/86 A CH537/86 A CH 537/86A CH 53786 A CH53786 A CH 53786A CH 672792 A5 CH672792 A5 CH 672792A5
- Authority
- CH
- Switzerland
- Prior art keywords
- peptide
- formula
- group
- residue
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70265185A | 1985-02-19 | 1985-02-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH672792A5 true CH672792A5 (es) | 1989-12-29 |
Family
ID=24822094
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH537/86A CH672792A5 (es) | 1985-02-19 | 1986-02-11 |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS61194097A (es) |
BE (1) | BE904233A (es) |
CH (1) | CH672792A5 (es) |
DE (1) | DE3604510A1 (es) |
FR (1) | FR2577557B1 (es) |
GB (1) | GB2171103B (es) |
IT (1) | IT1203743B (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5055450A (en) * | 1985-01-22 | 1991-10-08 | Ici Americas Inc. | Peptide derivatives |
US5194588A (en) * | 1985-01-22 | 1993-03-16 | Ici Americas Inc. | Aminoalcohol intermediates for peptide derivatives |
GB8600263D0 (en) * | 1985-01-22 | 1986-02-12 | Ici America Inc | Peptide derivatives |
US5496927A (en) * | 1985-02-04 | 1996-03-05 | Merrell Pharmaceuticals Inc. | Peptidase inhibitors |
US4882420A (en) * | 1985-04-19 | 1989-11-21 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
GB8613704D0 (en) * | 1986-06-05 | 1986-07-09 | Ici America Inc | Difluoro keto compounds |
GB8613703D0 (en) * | 1986-06-05 | 1986-07-09 | Ici America Inc | Difluoro peptide compounds |
GB8619182D0 (en) * | 1986-08-06 | 1986-09-17 | Sandoz Ltd | Peptides & derivatives |
NZ223148A (en) * | 1987-01-16 | 1989-10-27 | Merrell Dow Pharma | Peptide derivatives having peptidase inhibition activity |
US4855303A (en) * | 1987-07-01 | 1989-08-08 | Pfizer Inc. | Fluorine containing renin inhibitors |
US5071837A (en) * | 1990-11-28 | 1991-12-10 | Warner-Lambert Company | Novel renin inhibiting peptides |
US5559140A (en) * | 1991-01-02 | 1996-09-24 | Merrell Pharmaceuticals Inc. | Difluoro statone analogs |
NZ241099A (en) * | 1991-01-02 | 1994-08-26 | Merrell Dow Pharma | Difluorostatone analogues and derivatives and pharmaceutical compositions |
IL108031A0 (en) * | 1992-12-22 | 1994-04-12 | Procter & Gamble | Difluoro pentapeptide derivatives and pharmaceutical compositions containing them |
AU667995B2 (en) * | 1993-02-15 | 1996-04-18 | Bayer Aktiengesellschaft | New pseudopeptides having an antiviral action |
AU680009B2 (en) * | 1993-07-08 | 1997-07-17 | Aventisub Ii Inc. | Difluoro statone analogs |
AU683927B2 (en) * | 1993-09-09 | 1997-11-27 | Merrell Pharmaceuticals Inc. | Difluoro statone antiviral analogs |
US5969132A (en) * | 1994-02-04 | 1999-10-19 | Merrell Pharmaceuticals Inc. | Macrocyclic difluorostatone derivatives useful as antiviral agents |
GB9502152D0 (en) * | 1995-02-03 | 1995-03-29 | Zeneca Ltd | Proline derivatives |
US6114380A (en) * | 1995-12-18 | 2000-09-05 | Merrell Pharmaceuticals Inc. | Difluoro statone analogs |
US8324347B2 (en) | 2009-02-24 | 2012-12-04 | Institute For Systems Biology | Methods of using halogenated peptides as internal standards for liquid chromatography-mass spectrometry |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2424253A1 (fr) * | 1978-04-27 | 1979-11-23 | Brun Lab Sa Le | Nouveaux derives de peptides analogues des enkephalines, leur procede de preparation et leur application therapeutique |
EP0048159A3 (en) * | 1980-09-17 | 1982-05-12 | University Of Miami | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents |
EP0218688B1 (en) * | 1985-04-19 | 1990-09-12 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
-
1986
- 1986-02-11 CH CH537/86A patent/CH672792A5/de not_active IP Right Cessation
- 1986-02-13 DE DE19863604510 patent/DE3604510A1/de not_active Withdrawn
- 1986-02-17 BE BE1/011438A patent/BE904233A/fr not_active IP Right Cessation
- 1986-02-17 FR FR868602218A patent/FR2577557B1/fr not_active Expired - Lifetime
- 1986-02-17 GB GB08603835A patent/GB2171103B/en not_active Expired
- 1986-02-18 IT IT47666/86A patent/IT1203743B/it active
- 1986-02-18 JP JP61034930A patent/JPS61194097A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
GB8603835D0 (en) | 1986-03-26 |
BE904233A (fr) | 1986-08-18 |
FR2577557B1 (fr) | 1990-05-11 |
JPS61194097A (ja) | 1986-08-28 |
DE3604510A1 (de) | 1986-08-21 |
GB2171103B (en) | 1989-01-25 |
GB2171103A (en) | 1986-08-20 |
IT1203743B (it) | 1989-02-23 |
IT8647666A0 (it) | 1986-02-18 |
FR2577557A1 (fr) | 1986-08-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CH672792A5 (es) | ||
US5066643A (en) | Fluorine and chlorine statine or statone containing peptides and method of use | |
EP0236872B1 (de) | Hydroxylaminderivate, deren Herstellung und Verwendung für Heilmittel | |
AU600226B2 (en) | Novel peptidase inhibitors | |
EP0054862B1 (en) | Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase | |
US5496927A (en) | Peptidase inhibitors | |
EP0412350A2 (de) | Renininhibitoren, Verfahren zur Herstellung und ihre Verwendung in Arzneimitteln | |
NZ260675A (en) | Phosphinyloxymethyl ketones containing 1-3 amino acids as enzyme inhibitors; medicaments | |
EP0441192A2 (de) | Retroisostere Dipeptide, Verfahren zu ihrer Herstellung und ihre Verwendung als Renininhibitoren in Arzneimitteln | |
DE3000628C2 (es) | ||
DE69431359T2 (de) | Prolyl-endopeptidaseinhibitoren | |
EP0236874A2 (de) | Renininhibitoren, deren Herstellung und Verwendung sowie Aminosäure- und Aminoaldehyd-Derivate | |
DE69531459T2 (de) | Elatase-inhibitoren | |
EP0394853A1 (de) | Dipeptid-Derivate mit enzym-inhibitorischer Wirkung | |
DE4443390A1 (de) | Neue dipeptidische p-Amidinobenzylamide mit N-terminalen Sulfonyl- bzw. Aminosulfonylresten | |
EP0144290A2 (de) | Substituierte Aethylendiaminderivate | |
DE3884145T2 (de) | 4h-3,1-benzoxazin-4-on-verbindungen und serin protease-inhibierende arzneimittel. | |
EP0437729A2 (de) | Neue Peptide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel, insbesondere als Arzneimittel gegen Retroviren | |
EP0441191A2 (de) | Retroisostere Dipeptide, Verfahren zu ihrer Herstellung und ihre Verwendung als Renininhibitoren in Arzneimitteln | |
DE69913996T2 (de) | Depsipeptide, die nicht-natürliche Aminosäuren enthalten | |
EP0058567A1 (en) | Substituted acyl derivatives of octahydro-1H-isoindole-1-carboxylic acids and esters | |
DE69606552T2 (de) | Acylierte enolderivate von alpha-ketoestern und alpha-ketoamiden | |
DE3939747A1 (de) | Renininhibitorische peptide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln | |
DE69522940T2 (de) | Acylierte enolderivate als vorläufdrogen von elastaseinhibitoren | |
EP0203450B1 (de) | Neue Derivate bicyclischer Aminosäuren, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |