CH669383A5 - 2-Amino-4-hydroxy-thiazoline derivs. - Google Patents

2-Amino-4-hydroxy-thiazoline derivs. Download PDF

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Publication number
CH669383A5
CH669383A5 CH1282/85A CH128285A CH669383A5 CH 669383 A5 CH669383 A5 CH 669383A5 CH 1282/85 A CH1282/85 A CH 1282/85A CH 128285 A CH128285 A CH 128285A CH 669383 A5 CH669383 A5 CH 669383A5
Authority
CH
Switzerland
Prior art keywords
sep
groups
group
acid
formula
Prior art date
Application number
CH1282/85A
Other languages
German (de)
English (en)
Inventor
Hiroyuki Imaizumi
Takihiro Inaba
Ryuko Takeno
Seishi Morita
Yoshiharu Murotani
Junichi Yoshida
Kenichi Takashima
Shuntaro Takano
Isamu Saikawa
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59054522A external-priority patent/JPS60199894A/ja
Priority claimed from JP59062226A external-priority patent/JPS60208986A/ja
Priority claimed from JP59066649A external-priority patent/JPS60214783A/ja
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of CH669383A5 publication Critical patent/CH669383A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D501/06—Acylation of 7-aminocephalosporanic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH1282/85A 1984-03-23 1985-03-22 2-Amino-4-hydroxy-thiazoline derivs. CH669383A5 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP59054522A JPS60199894A (ja) 1984-03-23 1984-03-23 セファロスポリン類の新規製造法
JP59062226A JPS60208986A (ja) 1984-03-31 1984-03-31 新規セファロスポリン類およびその製造法
JP59066649A JPS60214783A (ja) 1984-04-05 1984-04-05 ２―アミノ―４―ヒドロキシチアゾリン誘導体およびその塩ならびにそれらの製造法

Publications (1)

Publication Number Publication Date
CH669383A5 true CH669383A5 (en) 1989-03-15

Family

ID=27295315

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1242/88A CH673460A5 (pl) 1984-03-23 1985-03-22
CH1282/85A CH669383A5 (en) 1984-03-23 1985-03-22 2-Amino-4-hydroxy-thiazoline derivs.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1242/88A CH673460A5 (pl) 1984-03-23 1985-03-22

Country Status (10)

Country Link
KR (1) KR870001796B1 (pl)
AR (1) AR243192A1 (pl)
AT (1) AT386207B (pl)
CH (2) CH673460A5 (pl)
DK (1) DK132585A (pl)
ES (1) ES541520A0 (pl)
FI (1) FI86184C (pl)
NO (1) NO167574C (pl)
PL (1) PL145915B1 (pl)
PT (1) PT80154B (pl)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0037380B1 (en) * 1980-03-28 1984-09-12 BIOCHEMIE Gesellschaft m.b.H. New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production

Also Published As

Publication number Publication date
NO851166L (no) 1985-09-24
NO167574B (no) 1991-08-12
FI86184B (fi) 1992-04-15
DK132585A (da) 1985-09-24
CH673460A5 (pl) 1990-03-15
FI851173L (fi) 1985-09-24
PT80154A (en) 1985-04-01
AR243192A1 (es) 1993-07-30
DK132585D0 (da) 1985-03-22
KR850006420A (ko) 1985-10-05
FI851173A0 (fi) 1985-03-22
ES8602814A1 (es) 1985-12-01
PL145915B1 (en) 1988-11-30
ATA86985A (de) 1987-12-15
AT386207B (de) 1988-07-25
NO167574C (no) 1991-11-20
ES541520A0 (es) 1985-12-01
KR870001796B1 (ko) 1987-10-12
FI86184C (fi) 1992-07-27
PT80154B (pt) 1987-06-17
PL252525A1 (en) 1985-12-17

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Date Code Title Description
PL Patent ceased