CH637909A5 - Removal of carboxyl-protecting groups - Google Patents

Removal of carboxyl-protecting groups Download PDF

Info

Publication number
CH637909A5
CH637909A5 CH814877A CH814877A CH637909A5 CH 637909 A5 CH637909 A5 CH 637909A5 CH 814877 A CH814877 A CH 814877A CH 814877 A CH814877 A CH 814877A CH 637909 A5 CH637909 A5 CH 637909A5
Authority
CH
Switzerland
Prior art keywords
reaction
carried out
benzyl ester
acid
ester
Prior art date
Application number
CH814877A
Other languages
German (de)
English (en)
Inventor
Teruji Tsuji
Mitsuru Yoshioka
Takahiro Kataoka
Yuji Sendo
Shoichi Hirai
Takashi Maeda
Wataru Nagata
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE19772725519 priority Critical patent/DE2725519A1/de
Priority to NLAANVRAGE7707240,A priority patent/NL188749C/nl
Application filed by Shionogi & Co filed Critical Shionogi & Co
Priority to CH814877A priority patent/CH637909A5/de
Priority to BE179054A priority patent/BE856444A/xx
Priority to FR7720919A priority patent/FR2396737A1/fr
Publication of CH637909A5 publication Critical patent/CH637909A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58—One oxygen atom, e.g. butenolide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH814877A 1977-06-06 1977-07-01 Removal of carboxyl-protecting groups CH637909A5 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE19772725519 DE2725519A1 (de) 1977-06-06 1977-06-06 Verfahren zur herstellung freier carbonsaeuren durch esterspaltung
NLAANVRAGE7707240,A NL188749C (nl) 1977-06-06 1977-06-29 Werkwijze voor het splitsen van esters van een desgewenst gesubstitueerde benzylalcohol.
CH814877A CH637909A5 (en) 1977-06-06 1977-07-01 Removal of carboxyl-protecting groups
BE179054A BE856444A (fr) 1977-06-06 1977-07-04 Elimination de radicaux protegeant la fonction carboxyle
FR7720919A FR2396737A1 (fr) 1977-06-06 1977-07-07 Procede d'enlevement des groupes de protection du radical carboxy par traitement d'esters benzyliques avec un acide de lewis et nouveaux produits ainsi obtenus

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE19772725519 DE2725519A1 (de) 1977-06-06 1977-06-06 Verfahren zur herstellung freier carbonsaeuren durch esterspaltung
NLAANVRAGE7707240,A NL188749C (nl) 1977-06-06 1977-06-29 Werkwijze voor het splitsen van esters van een desgewenst gesubstitueerde benzylalcohol.
CH814877A CH637909A5 (en) 1977-06-06 1977-07-01 Removal of carboxyl-protecting groups
BE179054A BE856444A (fr) 1977-06-06 1977-07-04 Elimination de radicaux protegeant la fonction carboxyle
BE856444 1977-07-04
FR7720919A FR2396737A1 (fr) 1977-06-06 1977-07-07 Procede d'enlevement des groupes de protection du radical carboxy par traitement d'esters benzyliques avec un acide de lewis et nouveaux produits ainsi obtenus

Publications (1)

Publication Number Publication Date
CH637909A5 true CH637909A5 (en) 1983-08-31

Family

ID=27543026

Family Applications (1)

Application Number Title Priority Date Filing Date
CH814877A CH637909A5 (en) 1977-06-06 1977-07-01 Removal of carboxyl-protecting groups

Country Status (5)

Country Link
BE (1) BE856444A (nl)
CH (1) CH637909A5 (nl)
DE (1) DE2725519A1 (nl)
FR (1) FR2396737A1 (nl)
NL (1) NL188749C (nl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0593615B1 (en) * 1991-07-10 1996-01-31 MERCK SHARP & DOHME LTD. Aromatic compounds, compositions containing them and their use in therapy
US5302711A (en) * 1992-02-18 1994-04-12 Eli Lilly And Company Ester cleavage process for use with β-lactams
US5922861A (en) * 1995-11-06 1999-07-13 Gist-Brocades B.V. De-esterification process
WO1997017352A1 (en) * 1995-11-06 1997-05-15 Gist-Brocades B.V. De-esterification process

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52106891A (en) * 1976-03-03 1977-09-07 Shionogi & Co Ltd Removal of carboxyl protecting group

Also Published As

Publication number Publication date
DE2725519C2 (nl) 1989-11-09
FR2396737B1 (nl) 1980-11-21
FR2396737A1 (fr) 1979-02-02
BE856444A (fr) 1977-10-31
NL7707240A (nl) 1979-01-03
NL188749C (nl) 1992-09-16
DE2725519A1 (de) 1978-12-21
NL188749B (nl) 1992-04-16

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PL Patent ceased