CH630613A5 - Verfahren zur herstellung von neuen, reaktiven unsymmetrischen dicarbonsaeureestern. - Google Patents

Verfahren zur herstellung von neuen, reaktiven unsymmetrischen dicarbonsaeureestern. Download PDF

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Publication number
CH630613A5
CH630613A5 CH1047576A CH1047576A CH630613A5 CH 630613 A5 CH630613 A5 CH 630613A5 CH 1047576 A CH1047576 A CH 1047576A CH 1047576 A CH1047576 A CH 1047576A CH 630613 A5 CH630613 A5 CH 630613A5
Authority
CH
Switzerland
Prior art keywords
digoxin
ester
oxy
radical
acid esters
Prior art date
Application number
CH1047576A
Other languages
German (de)
English (en)
Inventor
Hans-Georg Dr Batz
Hans-Ralf Dr Linke
Klaus Dr Stellner
Guenter Dr Weimann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of CH630613A5 publication Critical patent/CH630613A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/822Identified hapten
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/823Immunogenic carrier or carrier per se

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CH1047576A 1975-08-20 1976-08-17 Verfahren zur herstellung von neuen, reaktiven unsymmetrischen dicarbonsaeureestern. CH630613A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2537129A DE2537129C3 (de) 1975-08-20 1975-08-20 Reaktive unsymmetrische, einen Digoxin- bzw. Digitoxinrest enthaltende Dicarbonsäureester, Verfahren zu deren Herstellung sowie ihre Verwendung zur Herstellung von Testreagentien

Publications (1)

Publication Number Publication Date
CH630613A5 true CH630613A5 (de) 1982-06-30

Family

ID=5954435

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1047576A CH630613A5 (de) 1975-08-20 1976-08-17 Verfahren zur herstellung von neuen, reaktiven unsymmetrischen dicarbonsaeureestern.
CH25182A CH637659A5 (de) 1975-08-20 1982-01-15 Verfahren zur herstellung von reagentien zur bestimmung von herzglykosiden.

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH25182A CH637659A5 (de) 1975-08-20 1982-01-15 Verfahren zur herstellung von reagentien zur bestimmung von herzglykosiden.

Country Status (9)

Country Link
US (3) US4133949A (US07413550-20080819-C00001.png)
JP (1) JPS5855160B2 (US07413550-20080819-C00001.png)
AT (1) AT350040B (US07413550-20080819-C00001.png)
CH (2) CH630613A5 (US07413550-20080819-C00001.png)
DE (1) DE2537129C3 (US07413550-20080819-C00001.png)
FR (1) FR2321475A1 (US07413550-20080819-C00001.png)
GB (2) GB1518055A (US07413550-20080819-C00001.png)
IT (1) IT1064727B (US07413550-20080819-C00001.png)
NL (1) NL171989C (US07413550-20080819-C00001.png)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1107772B (it) * 1977-08-22 1985-11-25 Cancer Res Inst Royal Procedimento per la produzione di complessi macromolecolari prodotto ottenuto e composizioni farmaceutiche che lo contengono come ingrediente attivo
US4443621A (en) * 1983-03-14 1984-04-17 Pfizer Inc. p-Nitrophenyl 3-bromo-2,2-diethoxy-propionate and synthetic utility therefor
FR2574075B1 (fr) * 1984-12-04 1987-09-18 Poudres & Explosifs Ste Nale Procede de synthese d'esters actifs d'acides carboxyliques, nouveaux carbonates alpha-halogenes utiles pour cette synthese et leur mode d'obtention

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1668723A1 (de) * 1966-09-16 1971-04-08 Toyo Jozo Kk Verfahren zum Herstellen von Verbindungen mit Saeureamid-Bindung
US3963697A (en) * 1974-08-29 1976-06-15 Curtis Nuclear Corporation Labelled cardiotonic glycosides for use in radioimmunoassay

Also Published As

Publication number Publication date
NL171989C (nl) 1983-06-16
GB1518054A (en) 1978-07-19
US4436828A (en) 1984-03-13
AT350040B (de) 1979-05-10
GB1518055A (en) 1978-07-19
DE2537129C3 (de) 1978-05-03
FR2321475B1 (US07413550-20080819-C00001.png) 1982-06-18
US4282151A (en) 1981-08-04
NL171989B (nl) 1983-01-17
JPS5225722A (en) 1977-02-25
ATA433376A (de) 1978-10-15
DE2537129B2 (de) 1977-09-29
US4133949A (en) 1979-01-09
IT1064727B (it) 1985-02-25
DE2537129A1 (de) 1977-02-24
JPS5855160B2 (ja) 1983-12-08
NL7609014A (nl) 1977-02-22
FR2321475A1 (fr) 1977-03-18
CH637659A5 (de) 1983-08-15

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