CH628051A5 - Process for the preparation of N-alkylated derivatives of thienamycin - Google Patents
Process for the preparation of N-alkylated derivatives of thienamycin Download PDFInfo
- Publication number
- CH628051A5 CH628051A5 CH1462176A CH1462176A CH628051A5 CH 628051 A5 CH628051 A5 CH 628051A5 CH 1462176 A CH1462176 A CH 1462176A CH 1462176 A CH1462176 A CH 1462176A CH 628051 A5 CH628051 A5 CH 628051A5
- Authority
- CH
- Switzerland
- Prior art keywords
- carbon atoms
- radical
- alkyl
- group
- thienamycin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63429775A | 1975-11-21 | 1975-11-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH628051A5 true CH628051A5 (en) | 1982-02-15 |
Family
ID=24543224
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1462176A CH628051A5 (en) | 1975-11-21 | 1976-11-19 | Process for the preparation of N-alkylated derivatives of thienamycin |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS5277085A (fr) |
CH (1) | CH628051A5 (fr) |
DE (1) | DE2652676A1 (fr) |
DK (1) | DK523676A (fr) |
FR (1) | FR2332014A1 (fr) |
GB (1) | GB1570988A (fr) |
NL (1) | NL7612937A (fr) |
SE (1) | SE7612964L (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU531084B2 (en) * | 1977-10-19 | 1983-08-11 | Merck & Co., Inc. | Azetidine derivatives |
AU4061378A (en) * | 1977-10-19 | 1980-04-17 | Merck & Co., Inc. | 1-azabicyclo (3.2.0) hept-2-enes |
DE2966187D1 (en) * | 1978-08-23 | 1983-10-27 | Beecham Group Plc | Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them |
EP0082133A3 (en) * | 1979-04-19 | 1983-07-20 | Merck & Co. Inc. | A process for preparing intermediates useful for preparing 2-substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids |
US4376774A (en) * | 1979-05-29 | 1983-03-15 | Merck & Co., Inc. | Antibiotic N-heterocyclyl thienamycin |
DE3167774D1 (en) * | 1980-02-28 | 1985-01-31 | Fujisawa Pharmaceutical Co | 4-substituted-2-oxoazetidine compounds, processes for their preparation, and their use for preparing antibiotics |
JPS5798257A (en) * | 1980-12-10 | 1982-06-18 | Sankyo Co Ltd | 3,4-disubstituted azetidine-2-one compound and its preparation |
EP0062407A1 (fr) * | 1981-03-10 | 1982-10-13 | Beecham Group Plc | Composés thérapeutiques à cycle bête-lactame |
US4552696A (en) * | 1982-04-09 | 1985-11-12 | Bristol-Myers Company | Carbapenem antibiotics |
US4536335A (en) * | 1982-06-18 | 1985-08-20 | Bristol-Myers Company | Carbapenem antibiotics |
JPS5910588A (ja) * | 1982-06-18 | 1984-01-20 | ブリストル―マイヤーズ スクイブ カンパニー | カルバペネム抗生物質 |
MXPA06001115A (es) * | 2003-12-09 | 2006-04-11 | Choongwae Pharm Co | Un proceso nuevo para la preparacion de imipenem. |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3950357A (en) * | 1974-11-25 | 1976-04-13 | Merck & Co., Inc. | Antibiotics |
-
1976
- 1976-11-19 CH CH1462176A patent/CH628051A5/de not_active IP Right Cessation
- 1976-11-19 SE SE7612964A patent/SE7612964L/xx not_active Application Discontinuation
- 1976-11-19 GB GB48238/76A patent/GB1570988A/en not_active Expired
- 1976-11-19 NL NL7612937A patent/NL7612937A/xx not_active Application Discontinuation
- 1976-11-19 DK DK523676A patent/DK523676A/da unknown
- 1976-11-19 DE DE19762652676 patent/DE2652676A1/de not_active Withdrawn
- 1976-11-19 FR FR7634884A patent/FR2332014A1/fr active Granted
- 1976-11-22 JP JP51139653A patent/JPS5277085A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE2652676A1 (de) | 1977-06-02 |
JPS5277085A (en) | 1977-06-29 |
SE7612964L (sv) | 1977-05-22 |
GB1570988A (en) | 1980-07-09 |
NL7612937A (nl) | 1977-05-24 |
FR2332014B1 (fr) | 1978-11-10 |
FR2332014A1 (fr) | 1977-06-17 |
DK523676A (da) | 1977-05-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |