CH624848A5 - Therapeutic system for the administration of transdermally absorbable medicaments - Google Patents

Therapeutic system for the administration of transdermally absorbable medicaments Download PDF

Info

Publication number
CH624848A5
CH624848A5 CH142376A CH142376A CH624848A5 CH 624848 A5 CH624848 A5 CH 624848A5 CH 142376 A CH142376 A CH 142376A CH 142376 A CH142376 A CH 142376A CH 624848 A5 CH624848 A5 CH 624848A5
Authority
CH
Switzerland
Prior art keywords
layer
drug
polyisobutene
pad
membrane
Prior art date
Application number
CH142376A
Other languages
German (de)
English (en)
Inventor
John Urquhart
Santosh Kumar Chandrasekaran
Jane Elizabeth Shaw
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of CH624848A5 publication Critical patent/CH624848A5/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B7/00—Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
    • B32B7/04—Interconnection of layers
    • B32B7/12—Interconnection of layers using interposed adhesives or interposed materials with bonding properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/36—Layered products comprising a layer of synthetic resin comprising polyesters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/726—Permeability to liquids, absorption
    • B32B2307/7265—Non-permeable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2323/00—Polyalkenes
    • B32B2323/10—Polypropylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2367/00—Polyesters, e.g. PET, i.e. polyethylene terephthalate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2556/00—Patches, e.g. medical patches, repair patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Materials For Medical Uses (AREA)
CH142376A 1975-02-06 1976-02-05 Therapeutic system for the administration of transdermally absorbable medicaments CH624848A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54750475A 1975-02-06 1975-02-06

Publications (1)

Publication Number Publication Date
CH624848A5 true CH624848A5 (en) 1981-08-31

Family

ID=24184910

Family Applications (1)

Application Number Title Priority Date Filing Date
CH142376A CH624848A5 (en) 1975-02-06 1976-02-05 Therapeutic system for the administration of transdermally absorbable medicaments

Country Status (17)

Country Link
JP (1) JPS6049601B2 (nl)
AR (1) AR207805A1 (nl)
AT (1) AT344326B (nl)
AU (1) AU497383B2 (nl)
BE (1) BE838295A (nl)
CA (1) CA1059909A (nl)
CH (1) CH624848A5 (nl)
DE (1) DE2604718A1 (nl)
DK (1) DK145284C (nl)
ES (1) ES444552A1 (nl)
FR (1) FR2299853A1 (nl)
GB (1) GB1511121A (nl)
IL (1) IL48840A (nl)
IT (1) IT1057132B (nl)
NL (1) NL187379C (nl)
SE (1) SE424957B (nl)
ZA (1) ZA76234B (nl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5621589Y2 (nl) * 1977-05-30 1981-05-21
US4201211A (en) * 1977-07-12 1980-05-06 Alza Corporation Therapeutic system for administering clonidine transdermally
JPS5843368B2 (ja) * 1980-10-30 1983-09-27 日東電工株式会社 消炎鎮痛貼付剤
JPS5942314A (ja) * 1982-08-31 1984-03-08 Nitto Electric Ind Co Ltd 外用部材
JPS5984816A (ja) * 1982-11-08 1984-05-16 Sekisui Chem Co Ltd 薬剤徐放性製剤
IE54286B1 (en) * 1983-01-18 1989-08-16 Elan Corp Plc Drug delivery device
JPS6016916A (ja) * 1983-07-08 1985-01-28 Nitto Electric Ind Co Ltd 生物活性物質含有基剤及び該基剤の製法
DE3347277A1 (de) * 1983-12-28 1985-07-11 Bayer Ag, 5090 Leverkusen Wirkstoffabgabesysteme
DE3423293C2 (de) * 1984-06-23 1995-08-24 Lohmann Therapie Syst Lts Selbstklebendes Pflaster
DE3423328A1 (de) * 1984-06-23 1986-01-02 Beiersdorf Ag, 2000 Hamburg Selbstklebendes pflaster
US4588580B2 (en) * 1984-07-23 1999-02-16 Alaz Corp Transdermal administration of fentanyl and device therefor
IL72684A (en) * 1984-08-14 1989-02-28 Israel State Pharmaceutical compositions for controlled transdermal delivery of cholinergic or anticholinergic basic drugs
US4532244A (en) * 1984-09-06 1985-07-30 Innes Margaret N Method of treating migraine headaches
EP0249475A3 (en) * 1986-06-13 1989-10-11 Alza Corporation Delayed percutaneous delivery
FR2599976A1 (fr) * 1986-06-16 1987-12-18 Michel Pistor Dispositif therapeutique, portable, totalement autonome, transdermique, pourvu d'au moins un organe formant aiguille ou pointe franchissant la barriere cutanee
GB8700150D0 (en) * 1987-01-06 1987-02-11 Martin I F Wound dressings
CH674618A5 (nl) 1987-04-02 1990-06-29 Ciba Geigy Ag
GB2212063A (en) * 1987-11-12 1989-07-19 Original Norfolk Trading Co Lt Application of chemicals such as systemic herbicides and insecticides
FR2623718B1 (fr) * 1987-11-27 1994-04-15 Fabre Medicament Pierre Dispositif therapeutique transdermique et son procede de preparation
DE3823395A1 (de) * 1988-07-09 1990-03-15 Holzapfel Boeving Partner Werb Mit einem wirkstoff getraenktes tuch
DE4342174C1 (de) * 1993-12-10 1995-05-11 Lohmann Therapie Syst Lts Transdermales therapeutisches System sowie ein Verfahren zur Herstellung eines transdermalen therapeutischen Systems zur kombinierten transdermalen Anwendung von Physostigmin und Scopolamin für die Prophylaxe und zur Vorbehandlung einer Vergiftung durch hochtoxische phosphororganische Nervengifte, insbesondere Soman und seine Verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3767786A (en) * 1961-04-20 1973-10-23 Procter & Gamble Inhibiting perspiration with scopolamine esters
NL6902314A (nl) * 1969-02-13 1970-08-17
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
DE2012775C3 (de) * 1970-03-18 1973-10-04 V.P. Variopharm Gmbh Herstellung Und Vertrieb Pharmazeutischer, Kosmetischer Und Chemischer Erzeugnisse, 6656 Einoed Salbenfohe und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
BE838295A (fr) 1976-05-28
AT344326B (de) 1978-07-10
ZA76234B (en) 1977-01-26
SE7601204L (sv) 1976-08-09
JPS6049601B2 (ja) 1985-11-02
DK145284C (da) 1983-03-21
DK145284B (da) 1982-10-25
SE424957B (sv) 1982-08-23
DK47676A (da) 1976-08-07
NL187379C (nl) 1991-09-16
AU497383B2 (en) 1978-12-14
AU1067876A (en) 1977-08-04
JPS51104021A (nl) 1976-09-14
ES444552A1 (es) 1977-08-16
IL48840A0 (en) 1976-03-31
CA1059909A (en) 1979-08-07
IL48840A (en) 1978-01-31
NL187379B (nl) 1991-04-16
AR207805A1 (es) 1976-10-29
DE2604718A1 (de) 1976-08-19
NL7601248A (nl) 1976-08-10
ATA65676A (de) 1977-11-15
GB1511121A (en) 1978-05-17
DE2604718C2 (nl) 1987-03-05
FR2299853B1 (nl) 1978-08-18
FR2299853A1 (fr) 1976-09-03
IT1057132B (it) 1982-03-10

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Free format text: IKS 44708/930707, 960125

SPCR Supplementary protection certificate rejected

Free format text: IKS 44708/930707, 960125