CH622704A5 - - Google Patents

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Publication number
CH622704A5
CH622704A5 CH1226576A CH1226576A CH622704A5 CH 622704 A5 CH622704 A5 CH 622704A5 CH 1226576 A CH1226576 A CH 1226576A CH 1226576 A CH1226576 A CH 1226576A CH 622704 A5 CH622704 A5 CH 622704A5
Authority
CH
Switzerland
Prior art keywords
carbon atoms
hydrogen atom
alkyl group
disodium salt
composition according
Prior art date
Application number
CH1226576A
Other languages
German (de)
English (en)
Inventor
Manfred Dr Schmidt-Dunker
Wolfgang Dr Greb
Original Assignee
Henkel Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel Kgaa filed Critical Henkel Kgaa
Publication of CH622704A5 publication Critical patent/CH622704A5/de

Links

Classifications

    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21HOBTAINING ENERGY FROM RADIOACTIVE SOURCES; APPLICATIONS OF RADIATION FROM RADIOACTIVE SOURCES, NOT OTHERWISE PROVIDED FOR; UTILISING COSMIC RADIATION
    • G21H5/00Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for 
    • G21H5/02Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for  as tracers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0489Phosphates or phosphonates, e.g. bone-seeking phosphonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CH1226576A 1975-09-29 1976-09-28 CH622704A5 (US08066781-20111129-C00013.png)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2543349A DE2543349C2 (de) 1975-09-29 1975-09-29 Preaparate zur herstellung von99m technetium-radiagnostica

Publications (1)

Publication Number Publication Date
CH622704A5 true CH622704A5 (US08066781-20111129-C00013.png) 1981-04-30

Family

ID=5957719

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1226576A CH622704A5 (US08066781-20111129-C00013.png) 1975-09-29 1976-09-28

Country Status (13)

Country Link
US (1) US4104366A (US08066781-20111129-C00013.png)
JP (1) JPS5244243A (US08066781-20111129-C00013.png)
AT (1) AT357688B (US08066781-20111129-C00013.png)
AU (1) AU505502B2 (US08066781-20111129-C00013.png)
BE (1) BE846624A (US08066781-20111129-C00013.png)
CA (1) CA1059905A (US08066781-20111129-C00013.png)
CH (1) CH622704A5 (US08066781-20111129-C00013.png)
DE (1) DE2543349C2 (US08066781-20111129-C00013.png)
DK (1) DK408376A (US08066781-20111129-C00013.png)
FR (1) FR2325359A1 (US08066781-20111129-C00013.png)
GB (1) GB1503439A (US08066781-20111129-C00013.png)
NL (1) NL7609973A (US08066781-20111129-C00013.png)
ZA (1) ZA765814B (US08066781-20111129-C00013.png)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH630261A5 (de) * 1977-09-08 1982-06-15 Solco Basel Ag Verfahren und ampulle zur herstellung von radiopharmazeutika.
US4233284A (en) * 1978-03-31 1980-11-11 The Procter & Gamble Company Stabilized radiographic scanning agents
US4229427A (en) * 1978-06-28 1980-10-21 The Procter & Gamble Company Radioactive scanning agents with hydroquinone stabilizer
US4232000A (en) * 1978-06-28 1980-11-04 The Procter & Gamble Company Radioactive scanning agents with stabilizer
US4515766A (en) * 1980-06-23 1985-05-07 The Massachusetts General Hospital Labeled phosphonic acid compositions for investigations of in vivo deposits of calcium
DE3047107A1 (de) * 1980-12-13 1982-07-29 Hoechst Ag, 6000 Frankfurt Verfahren zur hertellung von 1-amino-alkan-1,1-diphosphonsaeuren
US4504462A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
US4440738A (en) * 1982-06-10 1984-04-03 Mallinckrodt, Inc. Stable radiographic imaging agents
US4504463A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
DE3237573A1 (de) * 1982-10-09 1984-04-12 Hoechst Ag, 6230 Frankfurt Technetium-99m-tri- und tetraphosphonate zur szintigraphischen dastellung res-haltiger organe und der lymphgefaesse und verfahren zu deren herstellung
US4898724A (en) * 1984-06-04 1990-02-06 The Dow Chemical Company Organis amine phosphonic acid complexes for the treatment of calcific tumors
US5066478A (en) * 1984-06-04 1991-11-19 The Dow Chemical Company Radio labeled organic amine phosphonic acid complexes for the treatment of calcific tumors
IL74902A (en) * 1984-06-04 1990-12-23 Dow Chemical Co Organic amine phosphonic acid complexes with particle-emitting radionuclides for the treatment of calcific tumors
US4687768A (en) * 1984-12-21 1987-08-18 The Procter & Gamble Company Certain hexahydroindan-2,2-diphosphonic acids useful in treating diseases associated with abnormal calcium and phosphate metabolism
US5104863A (en) * 1984-12-21 1992-04-14 The Procter & Gamble Company Certain bicycloalkane and azabicycloalkane-1,1-diphosphonic acid derivatives useful for treating diseases associated with abnormal calcium and phosphate metabolism
US4830847A (en) * 1985-06-28 1989-05-16 The Procter & Gamble Company Diphosphonate-derivatized macromolecules
JPS62185092A (ja) * 1986-02-07 1987-08-13 Teijin Ltd 新規ホスホン酸誘導体および除草剤
GB8615916D0 (en) * 1986-06-30 1986-08-06 Amersham Int Plc Bone-seeking complexes of technetium-99m
US4868164A (en) * 1986-12-19 1989-09-19 Norwich Eaton Pharmaceuticals, Inc. Octahydro-pyridine diphosphonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism
US5133956A (en) * 1991-05-30 1992-07-28 The Dow Chemical Company Radiolabeled metal-binding protein for the treatment of arthritis
EP1191948A2 (en) 1999-06-11 2002-04-03 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) * 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
WO2002062398A2 (en) 2001-01-08 2002-08-15 Neorx Corporation Radioactively labelled conjugates of phosphonates

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3989730A (en) * 1972-06-15 1976-11-02 Research Corporation Bone-seeking technetium-99m complex
US3851044A (en) * 1972-09-13 1974-11-26 New England Nuclear Corp Bone seeking technetium 99m stannous phosphate complex
US3965254A (en) * 1973-05-23 1976-06-22 The Procter & Gamble Company Compositions for the treatment of calcific tumors
US3983227A (en) * 1973-05-23 1976-09-28 The Procter & Gamble Company Dry mixture containing diphosphonates and a stannous salt useful in the preparation of Tc99M containing bone scanning agents
US3976762A (en) * 1974-07-05 1976-08-24 Minnesota Mining And Manufacturing Company Multi-organ technetium complexes production and use thereof
US3974268A (en) * 1975-05-30 1976-08-10 Research Corporation Bone-seeking technetium-99m imidodiphosphonate complex

Also Published As

Publication number Publication date
DE2543349A1 (de) 1977-04-07
JPS5244243A (en) 1977-04-07
AT357688B (de) 1980-07-25
FR2325359A1 (fr) 1977-04-22
ZA765814B (en) 1977-12-28
GB1503439A (en) 1978-03-08
AU505502B2 (en) 1979-11-22
JPS6133807B2 (US08066781-20111129-C00013.png) 1986-08-04
AU1718576A (en) 1978-03-02
CA1059905A (en) 1979-08-07
DK408376A (da) 1977-03-30
DE2543349C2 (de) 1984-05-10
US4104366A (en) 1978-08-01
FR2325359B1 (US08066781-20111129-C00013.png) 1978-11-17
BE846624A (fr) 1977-03-28
NL7609973A (nl) 1977-03-31
ATA718276A (de) 1979-12-15

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