CH619718A5 - - Google Patents

Download PDF

Info

Publication number
CH619718A5
CH619718A5 CH321077A CH321077A CH619718A5 CH 619718 A5 CH619718 A5 CH 619718A5 CH 321077 A CH321077 A CH 321077A CH 321077 A CH321077 A CH 321077A CH 619718 A5 CH619718 A5 CH 619718A5
Authority
CH
Switzerland
Prior art keywords
formula
compound
action
diastereoisomers
subjects
Prior art date
Application number
CH321077A
Other languages
English (en)
French (fr)
Inventor
Genevieve Rousseau
Vesperto Torelli
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of CH619718A5 publication Critical patent/CH619718A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/007—3 membered carbocyclic rings in position 6-7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
CH321077A 1976-03-16 1977-03-15 CH619718A5 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7607476A FR2344286A1 (fr) 1976-03-16 1976-03-16 Nouveaux derives 17-spirosultines, les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament

Publications (1)

Publication Number Publication Date
CH619718A5 true CH619718A5 (ko) 1980-10-15

Family

ID=9170470

Family Applications (1)

Application Number Title Priority Date Filing Date
CH321077A CH619718A5 (ko) 1976-03-16 1977-03-15

Country Status (10)

Country Link
US (1) US4093720A (ko)
JP (1) JPS52136156A (ko)
BE (1) BE852457A (ko)
CA (1) CA1096857A (ko)
CH (1) CH619718A5 (ko)
DE (1) DE2711516C2 (ko)
DK (1) DK142681B (ko)
FR (1) FR2344286A1 (ko)
GB (1) GB1532734A (ko)
NL (1) NL7702757A (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2569408B1 (fr) * 1984-08-24 1986-10-03 Roussel Uclaf Nouveaux steroides substitues en position 10 par un radical comportant une double ou triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
JPS63193059U (ko) * 1987-05-30 1988-12-13
JPH02106265U (ko) * 1989-02-10 1990-08-23
FR2681069B1 (fr) * 1991-09-06 1995-04-28 Roussel Uclaf Nouveau procede de preparation de l'hydrocortisone et nouveaux intermediaires.
US6043235A (en) * 1999-07-21 2000-03-28 Research Triangle Institute 11β-aryl-17, 17-spirothiolane-substituted steroids
CN116925169A (zh) * 2023-07-20 2023-10-24 浙江朗华制药有限公司 一种甾体化合物及其制备方法以及在坎利酮和螺内酯杂质研究中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD80023A (ko) *
US3383282A (en) 1965-04-07 1968-05-14 Upjohn Co 7alpha-methyl-3, 5-androstadiene-3, 17-diols and pharmaceutically active compositions thereof
DE2264189C3 (de) * 1972-12-29 1979-05-31 Merck & Co., Inc., Rahway, N.J. (V.St.A.) 3'-(3-Oxo-17beta-hydroxy-6,7-methylen-androst-4en-bzw.-l,4-dien-17 a-yl) -propionsäureverbindungen, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel
FR2216276B1 (ko) 1973-02-06 1976-11-05 Roussel Uclaf
FR2285137A1 (fr) * 1974-09-18 1976-04-16 Roussel Uclaf Nouveaux derives steroides 17-spirosultines, les g-hydroxyacides correspondants, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
DE2711516C2 (de) 1987-03-05
DK142681B (da) 1980-12-15
CA1096857A (fr) 1981-03-03
FR2344286B1 (ko) 1978-11-17
US4093720A (en) 1978-06-06
JPS52136156A (en) 1977-11-14
BE852457A (fr) 1977-09-15
DE2711516A1 (de) 1977-09-22
NL7702757A (nl) 1977-09-20
DK142681C (ko) 1981-08-03
DK112277A (ko) 1977-09-17
JPS6126557B2 (ko) 1986-06-20
FR2344286A1 (fr) 1977-10-14
GB1532734A (en) 1978-11-22

Similar Documents

Publication Publication Date Title
FR2584725A1 (fr) Androsta-1,4-diene-3,17-diones substituees, leur procede de fabrication et medicaments les contenant
EP0310519B1 (fr) Nouveaux esters d'acide androstane 17-carboxylique, procédé pour leur préparation et médicament les contenant
EP0056000B1 (fr) Dérivés 17/(alkoxycarbonyle) (formamido) méthylène/stéroides et leur préparation
EP0082049A2 (fr) Nouveaux éthers dont les restes organiques comportent des atomes chiraux, leur préparation, leur application au dédoublement d'alcools ou de certains composés hémiacétaliques et les nouveaux produits dédoublés obtenus
CH619718A5 (ko)
JPS59139400A (ja) 抗アルドステロン活性ステロイド誘導体
EP0001029B1 (fr) Procédé de préparation d'oximes en 3 de stéroides
CA1051419A (fr) Procede de preparation de nouveaux derives steroidiques
EP0012641B1 (fr) Dérivés 2-substitués du 19-nor-pregn-4-ène-3,20-dione, procédé pour leur préparation et compositions pharmaceutiques les renfermant
EP0018245B1 (fr) Nouveaux dérivés stéroides 7-alkylés, leur procédé de préparation, leur application comme médicament et les compositions pharmaceutiques les renfermant
EP0275728B1 (fr) Nouveaux produits stéroîdes comportant, en position 23, un radical sulfinyle, leur procédé de préparation, leur application à la préparation de produits de la série des 20-cétoprégnanes et des intermédiaires de cette application
CA1096372A (fr) Procede de preparation de nouveaux 2,2-dimethyl 19- nor steroides
CA1072540A (fr) Procede de preparation de nouveaux 2,2-dimethyl steroides
EP0055170B1 (fr) Nouveaux dérivés stéroides 3-céto delta 4 ou delta 1-4 substitués en position 7, leur préparation, leur application comme médicaments et les compositions les renfermant
EP0059146B1 (fr) Nouveaux médicaments dérivés de la 3-hydroxy dodécahydro benz (e) inden-7-one, produits dérivés de la 3-hydroxy dodécahydro benz (e) inden-7-one et leur procédé de préparation
CH627193A5 (ko)
EP0058097A2 (fr) Nouveau procédé de préparation de 17alpha-hydroxy 17bêta-hydroxyacétyl stéroides et produits intermédiaires correspondants obtenus
EP0000300A1 (fr) Estra-1,3,5(10),6-tétraènes substitués, procédé de préparation et application dans la synthèse de stéroides marqués au tritium
CH633714A5 (fr) Derives 17alpha-acetyleniques de l'androst 4-ene, procede de prepararation et compositions pharmaceutiques.
EP0375559B1 (fr) Nouveaux produits stéroides comportant un radical alkylthio en position 4, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant
CH629826A5 (en) Steroids, process for preparing them and their use in the synthesis of tritium-labelled steroids
EP0016665B1 (fr) Procédé de préparation de dérivés de la xanthone
FR2600254A1 (fr) Derives methylenes des androstene-4 diones-3, 17, leur procede de preparation, et leur application comme medicaments
CA1326235C (fr) Composes steroides utiles pour la preparation de produits de la serie 20-ceto pregnane
FR2478106A1 (fr) Nouveaux derives de steroide-spiro-oxathiazolidine, leur procede de preparation et medicaments les contenant

Legal Events

Date Code Title Description
PL Patent ceased