CH612675A5 - Process for the preparation of new 1-(2'-aroyl-1'-ethyl)-2-(4''-acetamido-1''-piperazinylmethyl)benzimidazo les - Google Patents
Process for the preparation of new 1-(2'-aroyl-1'-ethyl)-2-(4''-acetamido-1''-piperazinylmethyl)benzimidazo lesInfo
- Publication number
- CH612675A5 CH612675A5 CH12876A CH12876A CH612675A5 CH 612675 A5 CH612675 A5 CH 612675A5 CH 12876 A CH12876 A CH 12876A CH 12876 A CH12876 A CH 12876A CH 612675 A5 CH612675 A5 CH 612675A5
- Authority
- CH
- Switzerland
- Prior art keywords
- aroyl
- ethyl
- piperazinylmethyl
- acetamido
- benzimidazo
- Prior art date
Links
- 150000001556 benzimidazoles Chemical class 0.000 title abstract 2
- 208000002193 Pain Diseases 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- 206010020601 Hyperchlorhydria Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000007101 Muscle Cramp Diseases 0.000 abstract 1
- 206010030113 Oedema Diseases 0.000 abstract 1
- 208000008469 Peptic Ulcer Diseases 0.000 abstract 1
- 229910006124 SOCl2 Inorganic materials 0.000 abstract 1
- 208000005392 Spasm Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 238000005660 chlorination reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 231100000029 gastro-duodenal ulcer Toxicity 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- CWZMDINGMFZXMY-UHFFFAOYSA-N n-piperazin-1-ylacetamide Chemical compound CC(=O)NN1CCNCC1 CWZMDINGMFZXMY-UHFFFAOYSA-N 0.000 abstract 1
- 230000009278 visceral effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/10—Radicals substituted by halogen atoms or nitro radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7500724A FR2297045A1 (fr) | 1975-01-10 | 1975-01-10 | Nouveaux (aroyl-2' eth-1' yl)-1 (acetamido-4'' piperazin-1'' yl methyl)-2 benzimidazoles a proprietes antisecretoire gastrique et antiulcereuse |
| FR7537297A FR2333510A2 (fr) | 1975-12-05 | 1975-12-05 | Nouveaux (aroyl-2' eth-1 yl)-1 (acetamido-4'' piperazin-1'' yl methyl)-2 benzimidazoles, leur application en therapeutique et leur procede de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH612675A5 true CH612675A5 (en) | 1979-08-15 |
Family
ID=26218682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH12876A CH612675A5 (en) | 1975-01-10 | 1976-01-07 | Process for the preparation of new 1-(2'-aroyl-1'-ethyl)-2-(4''-acetamido-1''-piperazinylmethyl)benzimidazo les |
Country Status (13)
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2190439B1 (enrdf_load_html_response) * | 1972-07-06 | 1975-06-20 | Delalande Sa |
-
1975
- 1975-12-16 GB GB51396/75A patent/GB1487128A/en not_active Expired
- 1975-12-18 LU LU74043A patent/LU74043A1/xx unknown
- 1975-12-19 DE DE2557446A patent/DE2557446C2/de not_active Expired
-
1976
- 1976-01-03 ES ES444064A patent/ES444064A1/es not_active Expired
- 1976-01-06 MX MX001645U patent/MX3428E/es unknown
- 1976-01-07 CH CH12876A patent/CH612675A5/xx not_active IP Right Cessation
- 1976-01-08 AU AU10117/76A patent/AU509084B2/en not_active Expired
- 1976-01-08 SU SU762305959A patent/SU651701A3/ru active
- 1976-01-08 CA CA243,226A patent/CA1073455A/fr not_active Expired
- 1976-01-08 SE SE7600116A patent/SE421527B/xx unknown
- 1976-01-08 JP JP761833A patent/JPS6020386B2/ja not_active Expired
- 1976-01-09 IT IT67044/76A patent/IT1062803B/it active
- 1976-01-09 NL NL7600224A patent/NL7600224A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IT1062803B (it) | 1985-02-11 |
| CA1073455A (fr) | 1980-03-11 |
| MX3428E (es) | 1980-11-21 |
| ES444064A1 (es) | 1977-08-16 |
| NL7600224A (nl) | 1976-07-13 |
| AU509084B2 (en) | 1980-04-17 |
| LU74043A1 (enrdf_load_html_response) | 1976-11-11 |
| JPS6020386B2 (ja) | 1985-05-21 |
| AU1011776A (en) | 1977-07-14 |
| SU651701A3 (ru) | 1979-03-05 |
| SE7600116L (sv) | 1976-07-12 |
| DE2557446C2 (de) | 1984-11-29 |
| GB1487128A (en) | 1977-09-28 |
| DE2557446A1 (de) | 1976-07-15 |
| JPS51131885A (en) | 1976-11-16 |
| SE421527B (sv) | 1982-01-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |