US4780409A
(en)
*
|
1985-05-02 |
1988-10-25 |
Genetic Systems Corporation |
Thermally induced phase separation immunoassay
|
US4766106A
(en)
*
|
1985-06-26 |
1988-08-23 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polymer conjugation
|
US5206344A
(en)
*
|
1985-06-26 |
1993-04-27 |
Cetus Oncology Corporation |
Interleukin-2 muteins and polymer conjugation thereof
|
JPH0433452Y2
(hr)
*
|
1986-02-12 |
1992-08-11 |
|
|
US4959305A
(en)
*
|
1986-06-18 |
1990-09-25 |
Miles Inc. |
Reversible immobilization of assay reagents in a multizone test device
|
ES2058121T3
(es)
*
|
1986-09-17 |
1994-11-01 |
Beecham Group Plc |
Preparacion enzimatica inmovilizada y su uso.
|
US4894226A
(en)
*
|
1986-11-14 |
1990-01-16 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polyproline conjugation
|
US4847325A
(en)
*
|
1988-01-20 |
1989-07-11 |
Cetus Corporation |
Conjugation of polymer to colony stimulating factor-1
|
US5510418A
(en)
*
|
1988-11-21 |
1996-04-23 |
Collagen Corporation |
Glycosaminoglycan-synthetic polymer conjugates
|
US5306500A
(en)
*
|
1988-11-21 |
1994-04-26 |
Collagen Corporation |
Method of augmenting tissue with collagen-polymer conjugates
|
US5162430A
(en)
*
|
1988-11-21 |
1992-11-10 |
Collagen Corporation |
Collagen-polymer conjugates
|
US5565519A
(en)
*
|
1988-11-21 |
1996-10-15 |
Collagen Corporation |
Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
|
US5166322A
(en)
*
|
1989-04-21 |
1992-11-24 |
Genetics Institute |
Cysteine added variants of interleukin-3 and chemical modifications thereof
|
AU4104093A
(en)
*
|
1992-04-20 |
1993-11-18 |
Rufeld, Inc. |
Method and compositions for treatment of pyonecrotic processes
|
US5545553A
(en)
*
|
1994-09-26 |
1996-08-13 |
The Rockefeller University |
Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
|
US6833408B2
(en)
*
|
1995-12-18 |
2004-12-21 |
Cohesion Technologies, Inc. |
Methods for tissue repair using adhesive materials
|
US6458889B1
(en)
|
1995-12-18 |
2002-10-01 |
Cohesion Technologies, Inc. |
Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
|
ES2420106T3
(es)
*
|
1995-12-18 |
2013-08-22 |
Angiodevice International Gmbh |
Composiciones de polímeros reticulados y métodos para su uso
|
US7883693B2
(en)
|
1995-12-18 |
2011-02-08 |
Angiodevice International Gmbh |
Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
|
EP0874893A2
(en)
*
|
1995-12-29 |
1998-11-04 |
The Procter & Gamble Company |
Detergent compositions comprising immobilized enzymes
|
AU5104098A
(en)
*
|
1996-11-14 |
1998-06-03 |
Polymer Technology Corporation |
Use of water soluble enzyme-polymer conjugates for cleaning contact lenses
|
EP2599503B1
(en)
*
|
1998-10-16 |
2017-05-17 |
Biogen MA Inc. |
Polymer conjugates of interferon beta-1A and uses thereof
|
US7297511B2
(en)
*
|
2001-10-10 |
2007-11-20 |
Neose Technologies, Inc. |
Interferon alpha: remodeling and glycoconjugation of interferon alpha
|
US7795210B2
(en)
*
|
2001-10-10 |
2010-09-14 |
Novo Nordisk A/S |
Protein remodeling methods and proteins/peptides produced by the methods
|
US7157277B2
(en)
*
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
US7696163B2
(en)
|
2001-10-10 |
2010-04-13 |
Novo Nordisk A/S |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7179617B2
(en)
|
2001-10-10 |
2007-02-20 |
Neose Technologies, Inc. |
Factor IX: remolding and glycoconjugation of Factor IX
|
AU2004236174B2
(en)
|
2001-10-10 |
2011-06-02 |
Novo Nordisk A/S |
Glycopegylation methods and proteins/peptides produced by the methods
|
US7265085B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycoconjugation methods and proteins/peptides produced by the methods
|
US7173003B2
(en)
*
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
US7265084B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
US7226903B2
(en)
*
|
2001-10-10 |
2007-06-05 |
Neose Technologies, Inc. |
Interferon beta: remodeling and glycoconjugation of interferon beta
|
ZA200700168B
(en)
|
2001-10-10 |
2010-02-24 |
Novo Nordisk As |
Remodeling and glycoconjugation of peptides
|
US8008252B2
(en)
*
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
US7399613B2
(en)
*
|
2001-10-10 |
2008-07-15 |
Neose Technologies, Inc. |
Sialic acid nucleotide sugars
|
US7439043B2
(en)
*
|
2001-10-10 |
2008-10-21 |
Neose Technologies, Inc. |
Galactosyl nucleotide sugars
|
US7125843B2
(en)
*
|
2001-10-19 |
2006-10-24 |
Neose Technologies, Inc. |
Glycoconjugates including more than one peptide
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
CN102180944A
(zh)
*
|
2001-10-10 |
2011-09-14 |
诺和诺德公司 |
肽的重构和糖缀合
|
US7473680B2
(en)
*
|
2001-11-28 |
2009-01-06 |
Neose Technologies, Inc. |
Remodeling and glycoconjugation of peptides
|
MXPA04012496A
(es)
*
|
2002-06-21 |
2005-09-12 |
Novo Nordisk Healthcare Ag |
Glicoformos del factor vii pegilados.
|
US8129330B2
(en)
*
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
JP2006516548A
(ja)
|
2002-12-30 |
2006-07-06 |
アンジオテック インターナショナル アクツィエン ゲゼルシャフト |
迅速ゲル化ポリマー組成物からの薬物送達法
|
US20040219214A1
(en)
*
|
2002-12-30 |
2004-11-04 |
Angiotech International Ag |
Tissue reactive compounds and compositions and uses thereof
|
US7803777B2
(en)
*
|
2003-03-14 |
2010-09-28 |
Biogenerix Ag |
Branched water-soluble polymers and their conjugates
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
EP1613261A4
(en)
*
|
2003-04-09 |
2011-01-26 |
Novo Nordisk As |
INTRA-CELLULAR FORMATION OF PEPTIDE CONJUGATES
|
CA2524936A1
(en)
|
2003-05-09 |
2004-12-02 |
Neose Technologies, Inc. |
Compositions and methods for the preparation of human growth hormone glycosylation mutants
|
US9005625B2
(en)
|
2003-07-25 |
2015-04-14 |
Novo Nordisk A/S |
Antibody toxin conjugates
|
US8633157B2
(en)
*
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
US7405198B2
(en)
*
|
2003-11-24 |
2008-07-29 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US20080305992A1
(en)
*
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US7956032B2
(en)
*
|
2003-12-03 |
2011-06-07 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
US20060040856A1
(en)
*
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
KR101237884B1
(ko)
*
|
2003-12-03 |
2013-02-27 |
바이오제너릭스 에이지 |
글리코 peg화 과립구 콜로니 자극인자
|
US20080318850A1
(en)
*
|
2003-12-03 |
2008-12-25 |
Neose Technologies, Inc. |
Glycopegylated Factor Ix
|
ES2560657T3
(es)
|
2004-01-08 |
2016-02-22 |
Ratiopharm Gmbh |
Glicosilación con unión en O de péptidos G-CSF
|
JP4124361B2
(ja)
*
|
2004-02-16 |
2008-07-23 |
農工大ティー・エル・オー株式会社 |
化学物質の分離方法
|
CN104174071A
(zh)
|
2004-04-28 |
2014-12-03 |
安希奥设备国际有限责任公司 |
用于形成交联生物材料的组合物和系统及关联的制备方法与用途
|
WO2005111225A1
(en)
|
2004-05-04 |
2005-11-24 |
Novo Nordisk Health Care Ag |
O-linked glycoforms of polypeptides and method to manufacture them
|
US20080300173A1
(en)
|
2004-07-13 |
2008-12-04 |
Defrees Shawn |
Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
|
EP1799249A2
(en)
*
|
2004-09-10 |
2007-06-27 |
Neose Technologies, Inc. |
Glycopegylated interferon alpha
|
EP1796602A4
(en)
|
2004-09-17 |
2016-10-19 |
Angiotech Pharm Inc |
MULTIFUNCTIONAL COMPOUNDS FOR PRODUCING NETWORKED BIOMATERIALS AND MANUFACTURING AND USE METHOD THEREFOR
|
EP1797192A1
(en)
*
|
2004-09-29 |
2007-06-20 |
Novo Nordisk Health Care AG |
Modified proteins
|
DK2586456T3
(en)
|
2004-10-29 |
2016-03-21 |
Ratiopharm Gmbh |
Conversion and glycopegylation of fibroblast growth factor (FGF)
|
WO2006074279A1
(en)
*
|
2005-01-06 |
2006-07-13 |
Neose Technologies, Inc. |
Glycoconjugation using saccharyl fragments
|
EP1858543B1
(en)
|
2005-01-10 |
2013-11-27 |
BioGeneriX AG |
Glycopegylated granulocyte colony stimulating factor
|
US20060246544A1
(en)
*
|
2005-03-30 |
2006-11-02 |
Neose Technologies,Inc. |
Manufacturing process for the production of peptides grown in insect cell lines
|
EP2386571B1
(en)
|
2005-04-08 |
2016-06-01 |
ratiopharm GmbH |
Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
|
EP1888098A2
(en)
*
|
2005-05-25 |
2008-02-20 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin formulations
|
US20080255026A1
(en)
*
|
2005-05-25 |
2008-10-16 |
Glycopegylated Factor 1X |
Glycopegylated Factor Ix
|
CN102719508A
(zh)
*
|
2005-08-19 |
2012-10-10 |
诺和诺德公司 |
糖基聚乙二醇化的因子vii和因子viia
|
US20070105755A1
(en)
*
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
US20090048440A1
(en)
|
2005-11-03 |
2009-02-19 |
Neose Technologies, Inc. |
Nucleotide Sugar Purification Using Membranes
|
EP2049144B8
(en)
*
|
2006-07-21 |
2015-02-18 |
ratiopharm GmbH |
Glycosylation of peptides via o-linked glycosylation sequences
|
US20100075375A1
(en)
*
|
2006-10-03 |
2010-03-25 |
Novo Nordisk A/S |
Methods for the purification of polypeptide conjugates
|
LT2068907T
(lt)
*
|
2006-10-04 |
2018-01-10 |
Novo Nordisk A/S |
Glicerolio sujungti pegilinti sacharidai ir glikopeptidai
|
WO2008073620A2
(en)
*
|
2006-11-02 |
2008-06-19 |
Neose Technologies, Inc. |
Manufacturing process for the production of polypeptides expressed in insect cell-lines
|
CN101796063B
(zh)
|
2007-04-03 |
2017-03-22 |
拉蒂奥法姆有限责任公司 |
使用糖聚乙二醇化g‑csf的治疗方法
|
US20090053167A1
(en)
*
|
2007-05-14 |
2009-02-26 |
Neose Technologies, Inc. |
C-, S- and N-glycosylation of peptides
|
EP2162535A4
(en)
*
|
2007-06-04 |
2011-02-23 |
Novo Nordisk As |
O-linked glycosylation using N-acetylglucosamine transferases
|
ES2551123T3
(es)
*
|
2007-06-12 |
2015-11-16 |
Ratiopharm Gmbh |
Proceso mejorado para la producción de azúcares de nucleótido
|
RS53404B
(en)
|
2007-08-27 |
2014-10-31 |
Ratiopharm Gmbh |
LIQUID FORMULATION OF G-CSF CONJUGATES
|
US8207112B2
(en)
*
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
BRPI0816837B1
(pt)
|
2007-09-28 |
2022-10-18 |
Portola Pharmaceuticals, Inc |
Composições farmacêuticas, polipeptídeo isolado de duas cadeias e uso de uma composição farmacêutica
|
SG10202011946PA
(en)
|
2008-01-22 |
2020-12-30 |
Araim Pharmaceuticals Inc |
Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage
|
MX2010009154A
(es)
|
2008-02-27 |
2010-09-09 |
Novo Nordisk As |
Moleculas conjugadas del factor viii.
|
ES2438989T3
(es)
|
2008-05-13 |
2014-01-21 |
Advanced Liquid Logic, Inc. |
Dispositivos, sistemas y métodos accionadores de gotitas
|
IL235129B
(en)
|
2012-04-16 |
2022-06-01 |
Cantab Biopharmaceuticals Patents Ltd |
Therapeutic compounds for subcutaneous administration
|
EP3448415A4
(en)
|
2016-04-29 |
2019-11-06 |
Araim Pharmaceuticals, Inc. |
TISSUE PROTECTIVE PEPTIDES FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE INJURY
|