CH549029A - Verfahren zur herstellung von dihydrobenzodiazepinonen. - Google Patents
Verfahren zur herstellung von dihydrobenzodiazepinonen.Info
- Publication number
- CH549029A CH549029A CH582270A CH582270A CH549029A CH 549029 A CH549029 A CH 549029A CH 582270 A CH582270 A CH 582270A CH 582270 A CH582270 A CH 582270A CH 549029 A CH549029 A CH 549029A
- Authority
- CH
- Switzerland
- Prior art keywords
- dihydrobenzodiacepinones
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3060669 | 1969-04-18 | ||
JP3060169A JPS471928B1 (sv) | 1969-04-18 | 1969-04-18 | |
JP3060369 | 1969-04-18 | ||
JP3222069 | 1969-04-24 | ||
JP4187369 | 1969-05-28 | ||
JP4221369A JPS4834749B1 (sv) | 1969-05-29 | 1969-05-29 | |
JP5286869A JPS4828437B1 (sv) | 1969-07-03 | 1969-07-03 | |
JP6121869 | 1969-08-02 | ||
JP5454269 | 1969-08-15 | ||
JP6454269A JPS505195B1 (sv) | 1969-08-15 | 1969-08-15 | |
JP6510669 | 1969-08-18 | ||
DE19702017060 DE2017060C3 (de) | 1969-04-18 | 1970-04-09 | Verfahren zur Herstellung von 1,3-Dihydro-2H-1,4-benzodiazepinon-(2)derivaten |
DE19702065290 DE2065290C3 (de) | 1970-04-09 | 1 -(beta-Alkenyk>xy*Uiyl)-5-phenyl-7-chlor-1,3-dlhydro-2H-1,4-benzodiazepin-2-on-Oerivate und ihre Salze, Verfahren zu Ihrer Herstellung und Arzneimittel | |
GB1797470 | 1970-04-15 | ||
BE749136 | 1970-04-17 | ||
FR707014027A FR2042345B1 (sv) | 1969-04-18 | 1970-04-17 | |
NL7005566A NL7005566A (sv) | 1969-04-18 | 1970-04-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH549029A true CH549029A (de) | 1974-05-15 |
Family
ID=27585847
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH582270A CH549029A (de) | 1969-04-18 | 1970-04-17 | Verfahren zur herstellung von dihydrobenzodiazepinonen. |
CH1163470A CH539642A (de) | 1969-04-18 | 1970-07-31 | Verfahren zur Herstellung von Pyrimidinylpyrazolderivaten |
CH1234870A CH536310A (de) | 1969-04-18 | 1970-08-18 | Verfahren zur Herstellung von Dibenzazepin-Derivaten |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1163470A CH539642A (de) | 1969-04-18 | 1970-07-31 | Verfahren zur Herstellung von Pyrimidinylpyrazolderivaten |
CH1234870A CH536310A (de) | 1969-04-18 | 1970-08-18 | Verfahren zur Herstellung von Dibenzazepin-Derivaten |
Country Status (9)
Country | Link |
---|---|
US (2) | US3778433A (sv) |
AT (1) | AT303043B (sv) |
BE (1) | BE749136A (sv) |
CH (3) | CH549029A (sv) |
DE (2) | DE2065675A1 (sv) |
FR (2) | FR2042345B1 (sv) |
GB (2) | GB1309947A (sv) |
NL (2) | NL7005566A (sv) |
SE (2) | SE385701B (sv) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU162330B (sv) * | 1970-03-11 | 1973-01-29 | ||
GB1307144A (en) * | 1970-04-23 | 1973-02-14 | Sumitomo Chemical Co | Benzodiazepine derivatives processes for producing them and compo sitions containing them |
ES412186A1 (es) * | 1973-02-28 | 1976-01-01 | Made Labor Sa | Un procedimiento para la preparacion de derivados de tieno-diazepinona. |
US4208327A (en) * | 1979-04-03 | 1980-06-17 | G. D. Searle & Co. | 5-Aryl-1-(2-oxazolin-2-yl)-1H-1,4-benzodiazepines and related compounds |
US4405743A (en) * | 1979-08-31 | 1983-09-20 | Hokko Chemical Industry Co., Ltd. | Pyrazolylpyrimidine derivatives |
CA1332410C (en) * | 1984-06-26 | 1994-10-11 | Roger M. Freidinger | Benzodiazepine analogs |
US4820834A (en) * | 1984-06-26 | 1989-04-11 | Merck & Co., Inc. | Benzodiazepine analogs |
US5141735A (en) * | 1990-06-18 | 1992-08-25 | Hoffman-La Roche, Inc. | Substituted amino-benzodiazepines having anitviral activity |
TW312694B (sv) * | 1994-09-26 | 1997-08-11 | Daiichi Seiyaku Co | |
US7842693B2 (en) * | 2002-06-12 | 2010-11-30 | Chemocentryx, Inc. | Substituted piperazines |
DK1531822T3 (da) | 2002-06-12 | 2009-12-07 | Chemocentryx Inc | 1-aryl-4-substituerede piperazin derivater til anvendelse som CCR1 antagonister til behandlingen af inflammation og immunforstyrrelser |
US7589199B2 (en) | 2002-06-12 | 2009-09-15 | Chemocentryx, Inc. | Substituted piperazines |
US20050256130A1 (en) * | 2002-06-12 | 2005-11-17 | Chemocentryx, Inc. | Substituted piperazines |
AU2003288352A1 (en) * | 2002-10-30 | 2004-06-07 | Centre National De La Recherche Scientifique (Cnrs) | Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses |
FR2846653B1 (fr) * | 2002-10-30 | 2007-04-20 | Neuro3D | Inhibiteurs des phosphodiesterases des nucleotides cycliques, preparation et utilisations |
FR2850379B1 (fr) * | 2003-01-28 | 2006-11-17 | Aventis Pharma Sa | Produits n-aryl-heteroaromatiques, compositions les contenant et utilisation |
JP4845873B2 (ja) * | 2004-03-03 | 2011-12-28 | ケモセントリックス インコーポレーティッド | 二環式および架橋した窒素複素環 |
US7435831B2 (en) * | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
US8022061B2 (en) * | 2006-10-10 | 2011-09-20 | Amgen Inc. | N-aryl pyrazole compounds, compositions, and methods for their use |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1510315A (fr) * | 1966-02-03 | 1968-01-19 | Ciba Geigy | Procédé pour la préparation de 4-diaza-cyclo-alcano-pyrazoles substitués en position 1 par des restes hétérocycliques bicycliques |
CH535777A (de) * | 1967-03-01 | 1973-04-15 | Ciba Geigy Ag | Verfahren zur Herstellung neuer azacycloaliphatischer Verbindungen |
-
1970
- 1970-04-07 US US00026409A patent/US3778433A/en not_active Expired - Lifetime
- 1970-04-09 DE DE2065675*A patent/DE2065675A1/de active Pending
- 1970-04-15 GB GB1797470A patent/GB1309947A/en not_active Expired
- 1970-04-17 CH CH582270A patent/CH549029A/xx not_active IP Right Cessation
- 1970-04-17 NL NL7005566A patent/NL7005566A/xx unknown
- 1970-04-17 SE SE7005303A patent/SE385701B/sv unknown
- 1970-04-17 FR FR707014027A patent/FR2042345B1/fr not_active Expired
- 1970-04-17 BE BE749136D patent/BE749136A/xx unknown
- 1970-04-17 AT AT352270A patent/AT303043B/de not_active IP Right Cessation
- 1970-07-31 NL NL7011354A patent/NL7011354A/xx unknown
- 1970-07-31 FR FR7028456*A patent/FR2060076B1/fr not_active Expired
- 1970-07-31 GB GB37193/70A patent/GB1287659A/en not_active Expired
- 1970-07-31 SE SE10572/70A patent/SE367200B/xx unknown
- 1970-07-31 US US00060112A patent/US3723433A/en not_active Expired - Lifetime
- 1970-07-31 CH CH1163470A patent/CH539642A/de not_active IP Right Cessation
- 1970-08-03 DE DE19702038503 patent/DE2038503A1/de active Pending
- 1970-08-18 CH CH1234870A patent/CH536310A/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AT303043B (de) | 1972-11-10 |
DE2065675A1 (de) | 1974-11-21 |
FR2060076A1 (sv) | 1971-06-11 |
CH536310A (de) | 1973-04-30 |
DE2017060A1 (de) | 1970-10-29 |
DE2065290B2 (de) | 1976-09-09 |
DE2038503A1 (de) | 1971-02-25 |
FR2042345B1 (sv) | 1974-06-14 |
SE385701B (sv) | 1976-07-19 |
US3723433A (en) | 1973-03-27 |
BE749136A (fr) | 1970-10-01 |
FR2060076B1 (sv) | 1974-08-30 |
NL7005566A (sv) | 1970-10-20 |
CH539642A (de) | 1973-09-14 |
US3778433A (en) | 1973-12-11 |
FR2042345A1 (sv) | 1971-02-12 |
DE2017060B2 (de) | 1975-08-21 |
GB1287659A (en) | 1972-09-06 |
NL7011354A (sv) | 1971-02-04 |
GB1309947A (en) | 1973-03-14 |
DE2065290A1 (de) | 1973-04-26 |
SE367200B (sv) | 1974-05-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |