FR2042345B1 - - Google Patents
Info
- Publication number
- FR2042345B1 FR2042345B1 FR707014027A FR7014027A FR2042345B1 FR 2042345 B1 FR2042345 B1 FR 2042345B1 FR 707014027 A FR707014027 A FR 707014027A FR 7014027 A FR7014027 A FR 7014027A FR 2042345 B1 FR2042345 B1 FR 2042345B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (20)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00026409A US3778433A (en) | 1969-04-18 | 1970-04-07 | Process for producing benzodiazepine derivatives |
DE19702017060 DE2017060C3 (de) | 1969-04-18 | 1970-04-09 | Verfahren zur Herstellung von 1,3-Dihydro-2H-1,4-benzodiazepinon-(2)derivaten |
DE2065675*A DE2065675A1 (de) | 1969-04-18 | 1970-04-09 | 1,3-dihydro-2h-1,4-benzodiazepin-2-onderivate und ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE19702065290 DE2065290C3 (de) | 1970-04-09 | 1 -(beta-Alkenyk>xy*Uiyl)-5-phenyl-7-chlor-1,3-dlhydro-2H-1,4-benzodiazepin-2-on-Oerivate und ihre Salze, Verfahren zu Ihrer Herstellung und Arzneimittel | |
GB1797470A GB1309947A (en) | 1969-04-18 | 1970-04-15 | Benzodiazepine derivatives process for making them and compositions containing them |
NL7005566A NL7005566A (fr) | 1969-04-18 | 1970-04-17 | |
FR707014027A FR2042345B1 (fr) | 1969-04-18 | 1970-04-17 | |
AT352270A AT303043B (de) | 1969-04-18 | 1970-04-17 | Verfahren zur Herstellung von Benzodiazepinen bzw. von Säureadditionssalzen hievon |
BE749136D BE749136A (fr) | 1969-04-18 | 1970-04-17 | Nouveau procede de preparation de derives de benzodiazepines |
CH582270A CH549029A (de) | 1969-04-18 | 1970-04-17 | Verfahren zur herstellung von dihydrobenzodiazepinonen. |
SE7005303A SE385701B (sv) | 1969-04-18 | 1970-04-17 | Sett att framstella 1,4-bensodiazepinderivat |
SE10572/70A SE367200B (fr) | 1969-04-18 | 1970-07-31 | |
US00060112A US3723433A (en) | 1969-04-18 | 1970-07-31 | Pyrimidinylpyrazole derivatives and methods for preparing the same |
NL7011354A NL7011354A (fr) | 1969-04-18 | 1970-07-31 | |
GB37193/70A GB1287659A (en) | 1969-04-18 | 1970-07-31 | Pyrimidinylpyrazole derivatives |
FR7028456*A FR2060076B1 (fr) | 1969-04-18 | 1970-07-31 | |
CH1163470A CH539642A (de) | 1969-04-18 | 1970-07-31 | Verfahren zur Herstellung von Pyrimidinylpyrazolderivaten |
DE19702038503 DE2038503A1 (de) | 1969-04-18 | 1970-08-03 | Neue Pyrimidinylpyrazol-Derivate und Verfahren zu ihrer Herstellung |
CH1234870A CH536310A (de) | 1969-04-18 | 1970-08-18 | Verfahren zur Herstellung von Dibenzazepin-Derivaten |
US05/594,771 US3989829A (en) | 1969-04-18 | 1975-07-10 | 1,4-Benzodiazepines |
Applications Claiming Priority (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3060169A JPS471928B1 (fr) | 1969-04-18 | 1969-04-18 | |
JP3060369 | 1969-04-18 | ||
JP3060669 | 1969-04-18 | ||
JP3222069 | 1969-04-24 | ||
JP4187369 | 1969-05-28 | ||
JP4221369A JPS4834749B1 (fr) | 1969-05-29 | 1969-05-29 | |
JP5286869A JPS4828437B1 (fr) | 1969-07-03 | 1969-07-03 | |
JP6121869 | 1969-08-02 | ||
JP5454269 | 1969-08-15 | ||
JP6454269A JPS505195B1 (fr) | 1969-08-15 | 1969-08-15 | |
JP6510669 | 1969-08-18 | ||
DE19702065290 DE2065290C3 (de) | 1970-04-09 | 1 -(beta-Alkenyk>xy*Uiyl)-5-phenyl-7-chlor-1,3-dlhydro-2H-1,4-benzodiazepin-2-on-Oerivate und ihre Salze, Verfahren zu Ihrer Herstellung und Arzneimittel | |
DE19702017060 DE2017060C3 (de) | 1969-04-18 | 1970-04-09 | Verfahren zur Herstellung von 1,3-Dihydro-2H-1,4-benzodiazepinon-(2)derivaten |
GB1797470 | 1970-04-15 | ||
NL7005566A NL7005566A (fr) | 1969-04-18 | 1970-04-17 | |
FR707014027A FR2042345B1 (fr) | 1969-04-18 | 1970-04-17 | |
BE749136 | 1970-04-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2042345A1 FR2042345A1 (fr) | 1971-02-12 |
FR2042345B1 true FR2042345B1 (fr) | 1974-06-14 |
Family
ID=27585847
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR707014027A Expired FR2042345B1 (fr) | 1969-04-18 | 1970-04-17 | |
FR7028456*A Expired FR2060076B1 (fr) | 1969-04-18 | 1970-07-31 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7028456*A Expired FR2060076B1 (fr) | 1969-04-18 | 1970-07-31 |
Country Status (9)
Country | Link |
---|---|
US (2) | US3778433A (fr) |
AT (1) | AT303043B (fr) |
BE (1) | BE749136A (fr) |
CH (3) | CH549029A (fr) |
DE (2) | DE2065675A1 (fr) |
FR (2) | FR2042345B1 (fr) |
GB (2) | GB1309947A (fr) |
NL (2) | NL7005566A (fr) |
SE (2) | SE385701B (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU162330B (fr) * | 1970-03-11 | 1973-01-29 | ||
GB1307144A (en) * | 1970-04-23 | 1973-02-14 | Sumitomo Chemical Co | Benzodiazepine derivatives processes for producing them and compo sitions containing them |
ES412186A1 (es) * | 1973-02-28 | 1976-01-01 | Made Labor Sa | Un procedimiento para la preparacion de derivados de tieno-diazepinona. |
US4208327A (en) * | 1979-04-03 | 1980-06-17 | G. D. Searle & Co. | 5-Aryl-1-(2-oxazolin-2-yl)-1H-1,4-benzodiazepines and related compounds |
US4405743A (en) * | 1979-08-31 | 1983-09-20 | Hokko Chemical Industry Co., Ltd. | Pyrazolylpyrimidine derivatives |
CA1332410C (fr) * | 1984-06-26 | 1994-10-11 | Roger M. Freidinger | Analogues de benzodiazepines |
US4820834A (en) * | 1984-06-26 | 1989-04-11 | Merck & Co., Inc. | Benzodiazepine analogs |
US5141735A (en) * | 1990-06-18 | 1992-08-25 | Hoffman-La Roche, Inc. | Substituted amino-benzodiazepines having anitviral activity |
TW312694B (fr) * | 1994-09-26 | 1997-08-11 | Daiichi Seiyaku Co | |
US7589199B2 (en) | 2002-06-12 | 2009-09-15 | Chemocentryx, Inc. | Substituted piperazines |
US7842693B2 (en) * | 2002-06-12 | 2010-11-30 | Chemocentryx, Inc. | Substituted piperazines |
US20050256130A1 (en) * | 2002-06-12 | 2005-11-17 | Chemocentryx, Inc. | Substituted piperazines |
DE60328690D1 (de) * | 2002-06-12 | 2009-09-17 | Chemocentryx Inc | 1-aryl-4-substituierte piperazin-derivate zur verwendung als ccr1-antagonisten zur behandlung von entzündungen und immunerkrankungen |
CA2503716A1 (fr) * | 2002-10-30 | 2004-05-21 | Jean-Jacques Bourguignon | Utilisation d'inhibiteurs des phosphodiesterases des nucleotides cycliques, ayant une structure benzodiazepinique en therapie |
FR2846653B1 (fr) * | 2002-10-30 | 2007-04-20 | Neuro3D | Inhibiteurs des phosphodiesterases des nucleotides cycliques, preparation et utilisations |
FR2850379B1 (fr) * | 2003-01-28 | 2006-11-17 | Aventis Pharma Sa | Produits n-aryl-heteroaromatiques, compositions les contenant et utilisation |
WO2005084667A1 (fr) * | 2004-03-03 | 2005-09-15 | Chemocentryx, Inc. | Hétérocycles d'azote bicycliques et pontés |
US7435831B2 (en) * | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
TW200831491A (en) | 2006-10-10 | 2008-08-01 | Amgen Inc | N-aryl pyrazole compounds, compositions, and methods for their use |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3472857A (en) * | 1966-02-03 | 1969-10-14 | Ciba Ltd | N-(3-pyrazolyl-propyl)-n'-phenyl piperazines |
CH535777A (de) * | 1967-03-01 | 1973-04-15 | Ciba Geigy Ag | Verfahren zur Herstellung neuer azacycloaliphatischer Verbindungen |
-
1970
- 1970-04-07 US US00026409A patent/US3778433A/en not_active Expired - Lifetime
- 1970-04-09 DE DE2065675*A patent/DE2065675A1/de active Pending
- 1970-04-15 GB GB1797470A patent/GB1309947A/en not_active Expired
- 1970-04-17 NL NL7005566A patent/NL7005566A/xx unknown
- 1970-04-17 FR FR707014027A patent/FR2042345B1/fr not_active Expired
- 1970-04-17 CH CH582270A patent/CH549029A/xx not_active IP Right Cessation
- 1970-04-17 SE SE7005303A patent/SE385701B/xx unknown
- 1970-04-17 AT AT352270A patent/AT303043B/de not_active IP Right Cessation
- 1970-04-17 BE BE749136D patent/BE749136A/fr unknown
- 1970-07-31 US US00060112A patent/US3723433A/en not_active Expired - Lifetime
- 1970-07-31 CH CH1163470A patent/CH539642A/de not_active IP Right Cessation
- 1970-07-31 FR FR7028456*A patent/FR2060076B1/fr not_active Expired
- 1970-07-31 SE SE10572/70A patent/SE367200B/xx unknown
- 1970-07-31 GB GB37193/70A patent/GB1287659A/en not_active Expired
- 1970-07-31 NL NL7011354A patent/NL7011354A/xx unknown
- 1970-08-03 DE DE19702038503 patent/DE2038503A1/de active Pending
- 1970-08-18 CH CH1234870A patent/CH536310A/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BE749136A (fr) | 1970-10-01 |
DE2065290A1 (de) | 1973-04-26 |
SE385701B (sv) | 1976-07-19 |
AT303043B (de) | 1972-11-10 |
GB1287659A (en) | 1972-09-06 |
SE367200B (fr) | 1974-05-20 |
NL7005566A (fr) | 1970-10-20 |
FR2060076B1 (fr) | 1974-08-30 |
NL7011354A (fr) | 1971-02-04 |
DE2017060B2 (de) | 1975-08-21 |
CH536310A (de) | 1973-04-30 |
DE2065290B2 (de) | 1976-09-09 |
CH549029A (de) | 1974-05-15 |
DE2017060A1 (de) | 1970-10-29 |
US3778433A (en) | 1973-12-11 |
CH539642A (de) | 1973-09-14 |
DE2038503A1 (de) | 1971-02-25 |
GB1309947A (en) | 1973-03-14 |
FR2042345A1 (fr) | 1971-02-12 |
DE2065675A1 (de) | 1974-11-21 |
FR2060076A1 (fr) | 1971-06-11 |
US3723433A (en) | 1973-03-27 |
Similar Documents
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |