CH522407A - Procédé pour la préparation de solutions pour usages parentéral, oral et topique de la doxycycline - Google Patents

Procédé pour la préparation de solutions pour usages parentéral, oral et topique de la doxycycline

Info

Publication number
CH522407A
CH522407A CH933769A CH933769A CH522407A CH 522407 A CH522407 A CH 522407A CH 933769 A CH933769 A CH 933769A CH 933769 A CH933769 A CH 933769A CH 522407 A CH522407 A CH 522407A
Authority
CH
Switzerland
Prior art keywords
doxycycline
parenteral
oral
solutions
preparation
Prior art date
Application number
CH933769A
Other languages
English (en)
French (fr)
Inventor
Ernst Beutel Rolf
Christel Lohlbach Kathe
Wilhelm Raaf Helmut
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5699525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CH522407(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of CH522407A publication Critical patent/CH522407A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CH933769A 1968-06-28 1969-06-18 Procédé pour la préparation de solutions pour usages parentéral, oral et topique de la doxycycline CH522407A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1767891A DE1767891C3 (de) 1968-06-28 1968-06-28 Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat

Publications (1)

Publication Number Publication Date
CH522407A true CH522407A (fr) 1972-06-30

Family

ID=5699525

Family Applications (1)

Application Number Title Priority Date Filing Date
CH933769A CH522407A (fr) 1968-06-28 1969-06-18 Procédé pour la préparation de solutions pour usages parentéral, oral et topique de la doxycycline

Country Status (18)

Country Link
US (1) US3674859A (cg-RX-API-DMAC7.html)
AT (1) AT291441B (cg-RX-API-DMAC7.html)
BE (1) BE734723A (cg-RX-API-DMAC7.html)
BR (1) BR6909929D0 (cg-RX-API-DMAC7.html)
CH (1) CH522407A (cg-RX-API-DMAC7.html)
DE (1) DE1767891C3 (cg-RX-API-DMAC7.html)
DK (1) DK127168B (cg-RX-API-DMAC7.html)
ES (1) ES368496A1 (cg-RX-API-DMAC7.html)
FI (1) FI44395B (cg-RX-API-DMAC7.html)
FR (1) FR2011764B1 (cg-RX-API-DMAC7.html)
GB (1) GB1228629A (cg-RX-API-DMAC7.html)
IE (1) IE33167B1 (cg-RX-API-DMAC7.html)
IL (1) IL32350A (cg-RX-API-DMAC7.html)
MX (1) MX3351E (cg-RX-API-DMAC7.html)
MY (1) MY7300015A (cg-RX-API-DMAC7.html)
NL (1) NL6908919A (cg-RX-API-DMAC7.html)
NO (1) NO130624C (cg-RX-API-DMAC7.html)
SE (1) SE373036B (cg-RX-API-DMAC7.html)

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GB1350196A (en) * 1972-10-26 1974-04-18 Pfizer Doxycyline parenteral composition
US3957980A (en) * 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
US3928592A (en) * 1974-02-22 1975-12-23 Lilly Co Eli Antibiotic pharmaceutical compositions
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
GB1592053A (en) * 1976-12-16 1981-07-01 Norbrook Lab Ltd Oxytetracycline compositions
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
EP1666454B1 (en) * 1999-09-14 2011-09-07 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
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CA2404628A1 (en) 2000-03-31 2001-10-11 Stuart B. Levy 7-and 9-carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline compounds
ATE264295T1 (de) * 2000-05-15 2004-04-15 Paratek Pharm Innc 7-substituierte kondensierte ring-tetrazyclin- verbindungen
US20040224927A1 (en) 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
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JP4963771B2 (ja) 2000-07-07 2012-06-27 トラスティーズ・オブ・タフツ・カレッジ ７、８および９−置換テトラサイクリン化合物
MXPA03000056A (es) * 2000-07-07 2003-07-14 Tufts College Compuestos de tetraciclina sustituidos en posicion 7.
US7094806B2 (en) 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
CN1690047B (zh) 2000-07-07 2010-10-06 塔夫茨大学信托人 9-取代的二甲胺四环素化合物
EP1301465A2 (en) 2000-07-07 2003-04-16 Trustees Of Tufts College 13-substituted methacycline compounds
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
EA201000388A1 (ru) 2001-03-13 2010-10-29 Пэрэтек Фамэсьютикэлс, Инк. Замещенные соединения тетрациклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния субъекта
CA2440757A1 (en) 2001-03-14 2002-09-19 Michael Draper Substituted tetracycline compounds as synergistic antifungal agents
JP2004530661A (ja) 2001-03-14 2004-10-07 パラテック ファーマシューティカルズ インコーポレイテッド 抗真菌剤としての置換テトラサイクリン化合物
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
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EP2311798A1 (en) 2002-01-08 2011-04-20 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
CA2473931C (en) 2002-01-23 2010-10-26 Dentsply International, Inc. Irrigation solution and methods for use
CN102531948A (zh) 2002-03-08 2012-07-04 帕拉特克药品公司 氨基-甲基取代的四环素类化合物
JP2005520846A (ja) 2002-03-21 2005-07-14 パラテック ファーマシューティカルズ インコーポレイテッド 置換されたテトラサイクリン化合物。
EA012136B1 (ru) 2002-07-12 2009-08-28 Пэрэтек Фамэсьютикэлс, Инк. Замещенные соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
JP2006503898A (ja) 2002-10-24 2006-02-02 パラテック ファーマシューティカルズ， インク． マラリア治療のための置換テトラサイクリン化合物
AU2004259661B2 (en) 2003-07-09 2011-11-10 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
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US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
WO2005011707A1 (en) * 2003-07-25 2005-02-10 Warner Chilcott Company, Inc. A doxycycline metal complex in a solid dosage form
JP5010284B2 (ja) * 2004-01-15 2012-08-29 パラテック ファーマシューティカルズ インコーポレイテッド テトラサイクリン化合物の芳香族ａ環誘導体
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
CA2585418A1 (en) * 2004-10-25 2006-05-04 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
EP2284153A3 (en) 2004-10-25 2012-03-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
CA2595481C (en) * 2005-01-21 2014-05-13 Warner Chilcott Company, Inc. A tetracycline metal complex in a solid dosage form
AU2006210406C1 (en) * 2005-02-04 2013-03-07 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
US20070093455A1 (en) * 2005-07-21 2007-04-26 Paul Abato 10-substituted tetracyclines and methods of use thereof
AU2007208214B2 (en) * 2006-01-24 2013-02-14 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
JP4205731B2 (ja) * 2006-04-05 2009-01-07 株式会社日本触媒 ポリビニルピロリドン粉体組成物およびその製造方法
EP2007713A2 (en) * 2006-04-17 2008-12-31 Teva Pharmaceutical Industries Ltd Isolation of tetracycline derivatives
DK2016045T3 (en) * 2006-04-24 2015-02-02 Teva Pharma TIGECYCLIN CRYSTAL FORM AND PROCEDURES FOR PREPARING IT
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
JP2009543544A (ja) * 2006-05-15 2009-12-10 パラテック ファーマシューティカルズ インコーポレイテッド 置換されたテトラサイクリン化合物を用いて、遺伝子または遺伝子産物の発現を調節する方法
WO2008045507A2 (en) 2006-10-11 2008-04-17 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of bacillus anthracis infections
TR201818983T4 (tr) 2006-12-21 2019-01-21 Paratek Pharm Innc İnflamatuvar Cilt Bozukluklarının Tedavisine Yönelik Olarak Sübstitüe Edilmiş Tetrasiklin Bileşikleri
SI2109602T1 (sl) 2006-12-21 2014-06-30 Paratek Pharmaceuticals, Inc. Derivati tetraciklina za zdravljenje bakterijskih, virusnih in parazitskih infekcij
JP5121470B2 (ja) * 2007-01-26 2013-01-16 株式会社日本触媒 ポリビニルピロリドン粉体組成物
EP2144614A1 (en) * 2007-04-12 2010-01-20 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
WO2008134048A2 (en) 2007-04-27 2008-11-06 Paratek Pharmaceuticals, Inc. Methods for synthesizing and purifying aminoalkyl tetracycline compounds
JP2010532759A (ja) 2007-07-06 2010-10-14 パラテック ファーマシューティカルズ インコーポレイテッド 置換テトラサイクリン化合物を合成するための方法
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PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
AU2009236631A1 (en) * 2008-04-14 2009-10-22 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
TW202436282A (zh) 2008-05-19 2024-09-16 美商Ｐｒｔｋ Ｓｐｖ２公司 四環素化合物之甲苯磺酸鹽及同素異形體
CN102215681A (zh) * 2008-09-19 2011-10-12 帕拉特克药品公司 用于治疗类风湿性关节炎的四环素化合物和相关的治疗方法
US20120121706A1 (en) 2009-04-10 2012-05-17 Tufts Medical Center, Inc. PAR-1 Activation by Metalloproteinase-1 (MMP-1)
SG185513A1 (en) 2010-05-12 2012-12-28 Rempex Pharmaceuticals Inc Tetracycline compositions
CN101862293B (zh) * 2010-06-22 2012-02-29 华南农业大学 盐酸多西环素的油混悬液及其制备方法和应用
ES2739626T3 (es) 2011-05-12 2020-02-03 Paratek Pharm Innc Sales cristalinas de amida del ácido (4S,4aS,5aR,12aS)-4-dimetilamino-3,10,12,12a-tetrahidroxi-7-[(metoxi(metil)amino)-metil]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahidro-naftacen-2-carboxílico y métodos de uso de las mismas
PT108978B (pt) 2015-11-24 2020-03-09 Hovione Farm S A Sais de tetraciclinas
MY200446A (en) 2016-11-01 2023-12-26 Paratek Pharm Innc 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
MA49641A (fr) 2017-07-21 2021-06-02 Almirall Llc Traitement de lésions non inflammatoires

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (cg-RX-API-DMAC7.html) * 1960-05-23 1966-05-25

Also Published As

Publication number Publication date
ES368496A1 (es) 1971-05-01
IE33167B1 (en) 1974-04-03
FI44395B (cg-RX-API-DMAC7.html) 1971-08-02
FR2011764B1 (cg-RX-API-DMAC7.html) 1973-07-13
GB1228629A (cg-RX-API-DMAC7.html) 1971-04-15
IE33167L (en) 1969-12-28
BR6909929D0 (pt) 1973-02-08
AT291441B (de) 1971-07-12
IL32350A (en) 1972-05-30
DK127168B (da) 1973-10-01
IL32350A0 (en) 1969-08-27
US3674859A (en) 1972-07-04
BE734723A (cg-RX-API-DMAC7.html) 1969-12-18
MX3351E (es) 1980-10-08
MY7300015A (en) 1973-12-31
NO130624C (cg-RX-API-DMAC7.html) 1975-01-15
SE373036B (cg-RX-API-DMAC7.html) 1975-01-27
DE1767891B2 (de) 1980-02-21
NO130624B (cg-RX-API-DMAC7.html) 1974-10-07
DE1767891A1 (de) 1971-07-08
FR2011764A1 (cg-RX-API-DMAC7.html) 1970-03-06
NL6908919A (cg-RX-API-DMAC7.html) 1969-12-30
DE1767891C3 (de) 1980-10-30

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