CH498122A - Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates - Google Patents

Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Info

Publication number
CH498122A
CH498122A CH197668A CH197668A CH498122A CH 498122 A CH498122 A CH 498122A CH 197668 A CH197668 A CH 197668A CH 197668 A CH197668 A CH 197668A CH 498122 A CH498122 A CH 498122A
Authority
CH
Switzerland
Prior art keywords
preparation
new
tetrahydroazepine derivative
tetrahydroazepine
derivative
Prior art date
Application number
CH197668A
Other languages
German (de)
English (en)
Inventor
Karl Dr Hoegerle
Ernst Dr Habicht
Original Assignee
Geigy Ag J R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geigy Ag J R filed Critical Geigy Ag J R
Priority to CH197668A priority Critical patent/CH498122A/de
Priority to IL30458A priority patent/IL30458A/en
Priority to DK383268AA priority patent/DK123526B/da
Priority to NL6811311A priority patent/NL6811311A/xx
Priority to FR1598948D priority patent/FR1598948A/fr
Priority to AT797568A priority patent/AT277257B/de
Priority to ES357247A priority patent/ES357247A1/es
Priority to FR163036A priority patent/FR7915M/fr
Priority to DE19681795132 priority patent/DE1795132A1/de
Priority to GB38772/68A priority patent/GB1225053A/en
Priority to BE719631D priority patent/BE719631A/xx
Publication of CH498122A publication Critical patent/CH498122A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CH197668A 1967-02-17 1968-02-09 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates CH498122A (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CH197668A CH498122A (de) 1968-02-09 1968-02-09 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates
IL30458A IL30458A (en) 1968-02-09 1968-07-29 6-chloro-2,3,4,5-tetrahydro-1h-3-benzazepine,its preparation and compositions containing it
DK383268AA DK123526B (da) 1968-02-09 1968-08-08 Fremgangsmåde til fremstilling af 6-chlor-2,3,4,5-tetrahydro-1H-3-benzazepin eller syreadditionssalte deraf.
NL6811311A NL6811311A (cs) 1968-02-09 1968-08-08
FR1598948D FR1598948A (cs) 1968-02-09 1968-08-14
AT797568A AT277257B (de) 1968-02-09 1968-08-14 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates sowie seiner Säureadditionssalze
ES357247A ES357247A1 (es) 1968-02-09 1968-08-14 Procedimiento para la preparacion de un nuevo derivado de tetrahidroacepina.
FR163036A FR7915M (cs) 1967-02-17 1968-08-14
DE19681795132 DE1795132A1 (de) 1968-02-09 1968-08-14 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates
GB38772/68A GB1225053A (en) 1968-02-09 1968-08-14 New tetrahydroazepine derivative, process for its production and compositions containing same
BE719631D BE719631A (cs) 1968-02-09 1968-08-16

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH197668A CH498122A (de) 1968-02-09 1968-02-09 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Publications (1)

Publication Number Publication Date
CH498122A true CH498122A (de) 1970-10-31

Family

ID=4223010

Family Applications (1)

Application Number Title Priority Date Filing Date
CH197668A CH498122A (de) 1967-02-17 1968-02-09 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Country Status (10)

Country Link
AT (1) AT277257B (cs)
BE (1) BE719631A (cs)
CH (1) CH498122A (cs)
DE (1) DE1795132A1 (cs)
DK (1) DK123526B (cs)
ES (1) ES357247A1 (cs)
FR (1) FR1598948A (cs)
GB (1) GB1225053A (cs)
IL (1) IL30458A (cs)
NL (1) NL6811311A (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2207430C3 (de) * 1972-02-14 1982-05-13 Pennwalt Corp., 19102 Philadelphia, Pa. 1,2,4,5-Tetrahydro-3H-3-benzazepin, ein Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Mittel
US4160765A (en) * 1976-11-17 1979-07-10 Smithkline Corporation Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4197297A (en) * 1976-11-17 1980-04-08 Smithkline Corporation 6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
CN1805938B (zh) 2003-06-17 2010-06-16 艾尼纳制药公司 用于治疗5ht2c受体相关疾病的苯并氮杂卓衍生物
EA016485B1 (ru) 2003-06-17 2012-05-30 Арена Фармасьютикалз, Инк. Способы получения 3-бензазепинов
TW200510324A (en) * 2003-08-11 2005-03-16 Lilly Co Eli 6-(2,2,2-trifluoroethylamino)-7-chiloro-2, 3, 4, 5-tetrahydro-1h-benzo[d]azepine as a 5-ht2c receptor agonist
EA201200954A1 (ru) 2004-12-21 2013-05-30 Арена Фармасьютикалз, Инк. Способ получения полугидрата гидрохлорида (r)-8-хлор-1-метил-2,3,4,5-тетрагидро-1н-3-бензазепина, фармацевтическая композиция на его основе и его применение
PL1833473T3 (pl) 2004-12-23 2010-02-26 Arena Pharm Inc Kompozycje modulatora receptora 5HT2C i sposoby zastosowania
CN101466684B (zh) 2006-04-03 2012-06-20 艾尼纳制药公司 8-氯-1-甲基-2,3,4,5-四氢-1h-3-苯并氮杂卓的制备工艺和其相关中间体
US8299241B2 (en) 2006-12-05 2012-10-30 Arena Pharmaceuticals, Inc. Processes for preparing (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and intermediates thereof
CN102015591B (zh) 2008-03-04 2014-01-29 艾尼纳制药公司 制备与5-ht2c激动剂(r)-8-氯-1-甲基-2，3，4，5-四氢-1h-3-苯并氮杂卓相关的中间体的方法
CN102648170A (zh) 2009-06-18 2012-08-22 艾尼纳制药公司 制备5-ht2c受体激动剂的方法
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법
US9248133B2 (en) 2010-09-01 2016-02-02 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
KR20130101524A (ko) 2010-09-01 2013-09-13 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 아고니스트의 비-흡습성 염
CA2808912C (en) 2010-09-01 2019-09-17 Zezhi Jesse Shao Modified-release dosage forms of 5-ht2c agonists useful for weight management
AU2011296015B2 (en) 2010-09-01 2015-11-12 Arena Pharmaceuticals, Inc. Administration of lorcaserin to individuals with renal impairment
WO2014058441A1 (en) 2012-10-09 2014-04-17 Arena Pharmaceuticals, Inc. Method of weight management

Also Published As

Publication number Publication date
IL30458A0 (en) 1968-09-26
DK123526B (da) 1972-07-03
FR1598948A (cs) 1970-07-15
DE1795132A1 (de) 1972-01-05
BE719631A (cs) 1969-02-17
ES357247A1 (es) 1970-03-01
GB1225053A (en) 1971-03-17
AT277257B (de) 1969-12-29
NL6811311A (cs) 1969-08-12
IL30458A (en) 1972-03-28

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Legal Events

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PL Patent ceased