CH178441A - Process for the preparation of an asymmetric arsenic compound. - Google Patents

Process for the preparation of an asymmetric arsenic compound.

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Publication number
CH178441A
CH178441A CH178441DA CH178441A CH 178441 A CH178441 A CH 178441A CH 178441D A CH178441D A CH 178441DA CH 178441 A CH178441 A CH 178441A
Authority
CH
Switzerland
Prior art keywords
asymmetric
arsenic compound
preparation
compound
solution
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH178441A publication Critical patent/CH178441A/en

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  • Inorganic Compounds Of Heavy Metals (AREA)

Description

  

  Verfahren zur Herstellung einer asymmetrischen     Arsenoverbinddung,       Gegenstand der vorliegenden Erfindung  ist ein Verfahren zur Herstellung einer  asymmetrischen     Arsenoverbindung,    welches  dadurch gekennzeichnet ist; dass man     2.2'-          Dioxy    - 5 . 5'-     arsenopyridin    zusammen mit  4. 4'-     Diacetyldiaminoarseno    - 2 .     2'-phenoxy-          essigsäure    in alkalischer Lösung erwärmt und  aus der Lösung die asymmetrische     Arseno-          benzolverbindung    durch Ansäuern ausfällt.  



  Das Verfahrensprodukt ist ein gelbes, in       Alkalien    klar und mit neutraler Reaktion  lösliches Pulver. Es soll als Arzneimittel ver  wendet werden.  



  <I>Beispiel:</I>  <I>3,4</I>     gr-    2 .     :."-        Dioxy    - 5 . 5'-     arsenopyridin,     hergestellt nach Beispiel 1 der     deutschen     Patentschrift 528114, werden in 75 ein'  Wasser mit 20     em3        rr-NaOH    gelöst, in ana  loger     Wei,e    wie im Beispiel des Haupt  patentes 172872 beschrieben, mit einer  Lösung von 6,1     gr        4.4'-diacetyldiarr)irio-          arserio-2.2'-pheiioxyessigsaur-enr    Natrium in  150 cm' Wasser     vermischt    und auf dem    Dampfbad erhitzt.

   Das     Arsenobenzol    wird  mit Salzsäure ausgefällt. Es ist schon nach  einer halben     Stunde    in     Bicarbonatlösurlg    klar  löslich. Es kann wie im Beispiel des schweizer  Patentes 168364 beschrieben, aufgearbeitet  werden und ist dann identisch mit der, wie  dort beschrieben, erhaltenen Verbindung.



  Process for the production of an asymmetrical arsenic compound. The present invention relates to a process for the production of an asymmetrical arsenic compound, which is characterized; that one 2.2'-dioxy - 5. 5'-arsenopyridine together with 4. 4'-diacetyldiaminoarseno - 2. 2'-phenoxyacetic acid is heated in an alkaline solution and the asymmetric arsenobenzene compound is precipitated from the solution by acidification.



  The product of the process is a yellow powder that is clear in alkalis and soluble with a neutral reaction. It is intended to be used as a medicinal product.



  <I> Example: </I> <I> 3,4 </I> gr- 2. :. "- Dioxy - 5. 5'-arsenopyridine, prepared according to Example 1 of German Patent 528114, are dissolved in 75% water with 20 em3 rr-NaOH, in an analogous manner as described in the example of the main patent 172872 , mixed with a solution of 6.1 g of 4.4'-diacetyldiarr) irio-arserio-2.2'-pheiioxyessigsaur-enr sodium in 150 cm 'of water and heated on the steam bath.

   The arsenobenzene is precipitated with hydrochloric acid. It is clearly soluble in bicarbonate solution after only half an hour. It can be worked up as described in the example of Swiss patent 168364 and is then identical to the compound obtained as described there.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung einer asymmet rischen Arsenoverbindung, dadurch gekenn zeichnet, dass man 2.2'-Dioxy-5,5'-arseno- pyridin zusammen mit 4.4'-=Diacetyldiänrino- arseno-2.2'-plrenoxyessigsäure in alkalischer Lösung erwärmt und aus der Lösung die asymmetrische Arsenobenzolverbindung durch Ansäuern ausfällt. Das Verfahrensprodukt ist ein gelbes, in Alkalien klar und mit neutraler Reaktion lösliches Pulver. Es soll als Arzneimittel verwendet werden. PATENT CLAIM: Process for the production of an asymmetrical arsenic compound, characterized in that 2.2'-dioxy-5,5'-arsenopyridine is heated in alkaline solution together with 4.4 '- = diacetyldiänrino-arseno-2.2'-plrenoxyacetic acid and from the Solution, the asymmetric arsenobenzene compound precipitates by acidification. The product of the process is a yellow powder that is clear in alkalis and soluble with a neutral reaction. It is intended to be used as a medicine.
CH178441D 1932-08-06 1933-07-28 Process for the preparation of an asymmetric arsenic compound. CH178441A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE178441X 1932-08-06
CH172872T 1933-07-28

Publications (1)

Publication Number Publication Date
CH178441A true CH178441A (en) 1935-07-15

Family

ID=25719286

Family Applications (1)

Application Number Title Priority Date Filing Date
CH178441D CH178441A (en) 1932-08-06 1933-07-28 Process for the preparation of an asymmetric arsenic compound.

Country Status (1)

Country Link
CH (1) CH178441A (en)

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