CH167378A - Process for the preparation of 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride. - Google Patents

Process for the preparation of 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride.

Info

Publication number
CH167378A
CH167378A CH167378DA CH167378A CH 167378 A CH167378 A CH 167378A CH 167378D A CH167378D A CH 167378DA CH 167378 A CH167378 A CH 167378A
Authority
CH
Switzerland
Prior art keywords
acetylamino
chlorobenzene
methyl
sulfonic acid
acid chloride
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH167378A publication Critical patent/CH167378A/en

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

  

  Verfahren zur Darstellung von     1-.Aeetylamino-2-methyl-4-ehlorbenzol-          6-sulfonsäurechlorid.       Es wurde gefunden, dass man     1-Acetyl-          amino-2-methyl-4-chlorbenzol-    5     -.sulfonsäure-          chlorid    dadurch erhalten kann, dass man auf       1-Acetylamino-2-methyl-4-chlorbenzol        Chlor-          sulfonsäure        einwirken    lässt.  



  <I>Beispiel:</I>  183,5 Gewichtsteile     1-Acetylamino-2-me-          thyl-4-chlorbenzol    werden bei 20 bis<B>30'</B> in  1100 Gewichtsteile     Chlorsulfonsäure    einge  tragen und 20 Stunden bei 50 bis 55   ver  rührt. Nach dem Abkühlen auf Zimmer  temperatur wird das Reaktionsgemisch auf  3000 Gewichtsteile Eis gegeben, das dabei  in fester Form sich abscheidende     1-Acetyl-          amino-2-methyl-        4-chlorbenzol    - 5 -     sulfonsäure-          chlorid    wird von der sauren Brühe abgesaugt  und mit kaltem Wasser neutral gewaschen.

    Aus Aceton kristallisiert 1-Acetylamino-2-         methyl-4-chlorbenzol-5-sulfonsäurechlorid    in  farblosen Nadeln vom Schmelzpunkt 137  .  Es soll als Zwischenprodukt zum Aufbau  von Arzneimitteln, Farbstoffen usw. Ver  wendung     finden.  



  Process for the preparation of 1-acetylamino-2-methyl-4-chlorobenzene-6-sulfonic acid chloride. It has been found that 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride can be obtained by allowing chlorosulfonic acid to act on 1-acetylamino-2-methyl-4-chlorobenzene.



  <I> Example: </I> 183.5 parts by weight of 1-acetylamino-2-methyl-4-chlorobenzene are entered at 20 to <B> 30 '</B> in 1100 parts by weight of chlorosulfonic acid and for 20 hours at 50 stirred until 55. After cooling to room temperature, the reaction mixture is poured onto 3000 parts by weight of ice, the 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride which separates out in solid form is filtered off with suction from the acidic broth and mixed with cold Washed neutral with water.

    1-Acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride crystallizes from acetone in colorless needles with a melting point of 137. It is intended to be used as an intermediate in the synthesis of drugs, dyes, etc.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung von 1-Acetyl- amino-2-methyl- 4-ehlorbenzol - 5 - sulf onsäure- chlorid, dadurch gekennzeichnet, dass man auf 1-Acetylamino-2-methyl-4-chlorbenzol Chlorsulfonsäure einwirken lässt. Aus Aceton kristallisiert das neue Pro dukt in farblosen Nadeln vom Schmelzpunkt 137 . PATENT CLAIM: Process for the preparation of 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride, characterized in that chlorosulfonic acid is allowed to act on 1-acetylamino-2-methyl-4-chlorobenzene. The new product crystallizes from acetone in colorless needles with a melting point of 137.
CH167378D 1931-09-09 1932-08-26 Process for the preparation of 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride. CH167378A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE167378X 1931-09-09
CH163888T 1932-08-26

Publications (1)

Publication Number Publication Date
CH167378A true CH167378A (en) 1934-02-15

Family

ID=25717875

Family Applications (1)

Application Number Title Priority Date Filing Date
CH167378D CH167378A (en) 1931-09-09 1932-08-26 Process for the preparation of 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride.

Country Status (1)

Country Link
CH (1) CH167378A (en)

Similar Documents

Publication Publication Date Title
CH167378A (en) Process for the preparation of 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride.
CH167379A (en) Process for the preparation of 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride.
CH167377A (en) Process for the preparation of 1-acetylamino-2,4-dimethylbenzene-5-sulfonic acid chloride.
CH167376A (en) Process for the preparation of 1-benzoylamino-2-methoxybenzene-5-sulfonic acid chloride.
CH163888A (en) Process for preparing an acylaminosulfonic acid chloride of the benzene series.
CH167380A (en) Process for the preparation of 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride.
CH312530A (en) Process for making a pyridazone.
AT158872B (en) Process for the production of 5.5-disubstituted or 1.5.5-trisubstituted barbituric acids.
AT152837B (en) Process for the preparation of 2.4-dioxo-3.3-dialkyl-1.2.3.4-tatrahydropyridines.
AT118644B (en) Process for the preparation of 0,0-diacetyldiphenolisatin.
AT43882B (en) Process for the preparation of the alkyl pseudoisatins.
AT92407B (en) Process for the preparation of 1-allyl-3,7-dimethylxanthine.
CH139373A (en) Process for the preparation of 1,4-Dioxy-6-methyl-8-chlorobenzo-thiophanthrenequinone.
CH142341A (en) Process for the preparation of 2-chloro-4- (di- (oxyethyl)) -amino-1-oxybenzene.
CH170087A (en) Process for the preparation of an oxycarboxylic acid.
CH312527A (en) Process for the preparation of a new pyridine derivative.
CH128995A (en) Process for the preparation of 2-oxynaphthalene-3-sulfo-6-carboxylic acid.
CH333078A (en) Process for the production of new anesthetic agents
CH310732A (en) Process for the preparation of a bactericidal salicylanilide.
CH174886A (en) Process for the preparation of an oxycarboxylic acid.
CH209509A (en) Process for the preparation of an aminoarylsulfone.
CH222077A (en) Process for the preparation of a condensation product.
CH261821A (en) Process for the preparation of a substituted 2,4-diamino-1,3,5-triazine.
CH180874A (en) Process for the preparation of an acylated dihydrofollicle hormone.
CH307808A (en) Process for the preparation of a new hydrazine compound.