CH167379A - Process for the preparation of 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride. - Google Patents
Process for the preparation of 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride.Info
- Publication number
- CH167379A CH167379A CH167379DA CH167379A CH 167379 A CH167379 A CH 167379A CH 167379D A CH167379D A CH 167379DA CH 167379 A CH167379 A CH 167379A
- Authority
- CH
- Switzerland
- Prior art keywords
- acetylamino
- chlorobenzene
- sulfonic acid
- acid chloride
- preparation
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
Verfahren zur Darstellung von 1-Aeetylamino-2-methozy-4-eblorbenzol-5- snlfonsäureehlorid, Es wurde gefunden, dass man 1-Acetyl amino-2-methoxy-4-chlorbenzol-5-sulfonsäure- chlorid dadurch erhalten kann, dass man auf 1-Acetylamino-2-methoxy-4-chlorbenzol Chlorsulfonsäure einwirken lässt.
<I>Beispiel:</I> 199,5 Gewichtsteile 1-Acetylamino-2-me- thoxy-4-chlorbenzol werden bei 20 bis<B>30'</B> in 1200 Gewichtsteile Chlorsulfonsäure einge tragen und 20 Stunden bei<B>50'</B> verrührt. Nach dem Abkühlen auf Zimmertemperatur wird das Reaktionsgemisch auf 3000 Ge wichtsteile Eis gegeben, das dabei in fester Form sich abscheidende 1-Acetylamino-2-me- tlioxy-4-chlorbenzol-5-sulfonsäurechlorid wird von der sauren Brühe abgesaugt und mit kaltem Wasser neutral gewaschen.
Aus Ace ton kristallisiert 1-Acetyl-amino-2-methoxy- 4-chlorbenzol-5-sulfonsäurechlorid in farb losen Nadeln vom Schmelzpunkt<B>160'.</B> Es soll als Zwischenprodukt zum Aufbau von Farbstoffen, Arzneimitteln usw. Verwen dung finden.
Process for the preparation of 1-acetylamino-2-methoxy-4-ebobenzene-5-sulfonic acid chloride. It has been found that 1-acetylamino-2-methoxy-4-chlorobenzene-5-sulfonic acid chloride can be obtained by leaves chlorosulfonic acid to act on 1-acetylamino-2-methoxy-4-chlorobenzene.
<I> Example: </I> 199.5 parts by weight of 1-acetylamino-2-methoxy-4-chlorobenzene are entered at 20 to <B> 30 '</B> in 1200 parts by weight of chlorosulfonic acid and for 20 hours at < B> 50 '</B> stirred. After cooling to room temperature, the reaction mixture is poured onto 3000 parts by weight of ice, the 1-acetylamino-2-metlioxy-4-chlorobenzene-5-sulfonic acid chloride which separates out in solid form is suctioned off from the acidic broth and neutralized with cold water washed.
1-Acetyl-amino-2-methoxy-4-chlorobenzene-5-sulfonic acid chloride crystallizes from acetone in colorless needles with a melting point of <B> 160 '. </B> It is intended to be used as an intermediate product in the synthesis of dyes, drugs, etc. find application.
Claims (1)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE167379X | 1931-09-09 | ||
| CH163888T | 1932-08-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH167379A true CH167379A (en) | 1934-02-15 |
Family
ID=25717876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH167379D CH167379A (en) | 1931-09-09 | 1932-08-26 | Process for the preparation of 1-acetylamino-2-methyl-4-chlorobenzene-5-sulfonic acid chloride. |
Country Status (1)
| Country | Link |
|---|---|
| CH (1) | CH167379A (en) |
-
1932
- 1932-08-26 CH CH167379D patent/CH167379A/en unknown
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