CH142064A - Process for the production of a pharmaceutical preparation. - Google Patents

Process for the production of a pharmaceutical preparation.

Info

Publication number
CH142064A
CH142064A CH142064DA CH142064A CH 142064 A CH142064 A CH 142064A CH 142064D A CH142064D A CH 142064DA CH 142064 A CH142064 A CH 142064A
Authority
CH
Switzerland
Prior art keywords
production
pharmaceutical preparation
alcohol
preparation
phenyldihydroquinazoline
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH142064A publication Critical patent/CH142064A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

  

  Verfahren zur Herstellung eines pharmazeutischen Präparates.    Im Hauptpatent ist ein Verfahren zur  Darstellung eines zur therapeutischen Dar  reichung besonders geeigneten Salzes einer  aromatischen Base beschrieben, das dadurch  gekennzeichnet ist, dass man auf     p-Oxyben-          zoyl-o-benzoesäure,        3-Phenyldihydrochinazolin     einwirken lässt.  



  Gegenstand vorliegender Erfindung ist  nun ein Verfahren zur Darstellung eines zur  therapeutischen Darreichung besonders geeig  neten Salzes einer aromatischen Base, das  dadurch gekennzeichnet ist, dass man     2.4-          Dioxybenzoyl-2'-benzoesäure    mit     3-Phenyldi-          hydrochinazolin    umsetzt.

      <I>Beispiel:</I>    258 Gewichtsteile     2.4-Dioxybenzoyl-2'-          benzoesäure     
EMI0001.0010     
    löst man in 2500 Gewichtsteilen Alkohol    und lässt in diese Lösung eine Auflösung von  208 Gewichtsteilen     3-Phenyldihydrochinazolin     in 1000 Gewichtsteilen Alkohol     einfliessen.     Die abgeschiedenen Kristalle werden abge  saugt. Sie bilden nach dem     Ümlösen    aus  heissem Alkohol farblose, glasglänzende Pris  men, die bei 100  unter Abgabe von     111Iol.     Kristallalkohol verwittern. Schmelzpunkt 119 .



  Process for the production of a pharmaceutical preparation. The main patent describes a process for the preparation of a salt of an aromatic base which is particularly suitable for therapeutic administration and which is characterized in that p-oxybenzoyl-o-benzoic acid, 3-phenyldihydroquinazoline, is allowed to act.



  The present invention now relates to a process for the preparation of a salt of an aromatic base which is particularly suitable for therapeutic administration and which is characterized in that 2,4-dioxybenzoyl-2'-benzoic acid is reacted with 3-phenyldihydroquinazoline.

      <I> Example: </I> 258 parts by weight of 2,4-dioxybenzoyl-2'-benzoic acid
EMI0001.0010
    it is dissolved in 2500 parts by weight of alcohol and a dissolution of 208 parts by weight of 3-phenyldihydroquinazoline in 1000 parts by weight of alcohol is allowed to flow into this solution. The deposited crystals are filtered off with suction. After dissolving from hot alcohol, they form colorless, glass-glossy prisms which, at 100, release 111Iol. Weathering crystal alcohol. Melting point 119.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung eines zur thera peutischen Darreichung besonders geeigneten Salzes einer aromatischen Base, dadurch gekennzeichnet, dass man 2-4-Dioxybenzoyl- 2'-benzoesäure mit 3-Phenyldihydrochinazolin umsetzt. Die neue Verbindung kristallisiert aus Al kohol in glasglänzenden farblosen Prismen die bei 1000 unter Abgabe von 1 bTol. Kri stallalkohol verwittern. Fp. 119 C. PATENT CLAIM: Process for the preparation of a salt of an aromatic base particularly suitable for therapeutic administration, characterized in that 2-4-dioxybenzoyl-2'-benzoic acid is reacted with 3-phenyldihydroquinazoline. The new compound crystallizes from alcohol in glossy, colorless prisms which at 1000 release 1 btol. Weathering crystal alcohol. M.p. 119 C.
CH142064D 1927-10-06 1928-10-01 Process for the production of a pharmaceutical preparation. CH142064A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE142064X 1927-10-06
CH139015T 1928-10-01

Publications (1)

Publication Number Publication Date
CH142064A true CH142064A (en) 1930-08-31

Family

ID=25713282

Family Applications (1)

Application Number Title Priority Date Filing Date
CH142064D CH142064A (en) 1927-10-06 1928-10-01 Process for the production of a pharmaceutical preparation.

Country Status (1)

Country Link
CH (1) CH142064A (en)

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