CA3197199A1 - Compounds and compositions for the treatment of cryptosporidiosis - Google Patents

Compounds and compositions for the treatment of cryptosporidiosis

Info

Publication number
CA3197199A1
CA3197199A1 CA3197199A CA3197199A CA3197199A1 CA 3197199 A1 CA3197199 A1 CA 3197199A1 CA 3197199 A CA3197199 A CA 3197199A CA 3197199 A CA3197199 A CA 3197199A CA 3197199 A1 CA3197199 A1 CA 3197199A1
Authority
CA
Canada
Prior art keywords
methyl
carboxamido
pyridine
methylpyrazolo
chlorobenzoate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3197199A
Other languages
English (en)
French (fr)
Inventor
Joseph Michael YOUNG
Michael Robert Turner
Peichao Lu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of CA3197199A1 publication Critical patent/CA3197199A1/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA3197199A 2020-10-14 2021-10-12 Compounds and compositions for the treatment of cryptosporidiosis Pending CA3197199A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063091866P 2020-10-14 2020-10-14
US63/091,866 2020-10-14
PCT/IB2021/059376 WO2022079616A1 (en) 2020-10-14 2021-10-12 Compounds and compositions for the treatment of cryptosporidiosis

Publications (1)

Publication Number Publication Date
CA3197199A1 true CA3197199A1 (en) 2022-04-21

Family

ID=78302850

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3197199A Pending CA3197199A1 (en) 2020-10-14 2021-10-12 Compounds and compositions for the treatment of cryptosporidiosis

Country Status (12)

Country Link
US (1) US12018024B2 (https=)
EP (1) EP4229055B1 (https=)
JP (1) JP7791184B2 (https=)
CN (1) CN116368137A (https=)
AR (1) AR123766A1 (https=)
AU (1) AU2021362803A1 (https=)
CA (1) CA3197199A1 (https=)
MX (1) MX2023004435A (https=)
PY (1) PY2189412A (https=)
TW (1) TW202229277A (https=)
UY (1) UY39466A (https=)
WO (1) WO2022079616A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR132352A1 (es) * 2023-04-13 2025-06-18 Syngenta Crop Protection Ag Derivados de imidazo[1,2-a]pirazina

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2925757T (lt) 2012-11-19 2017-12-27 Novartis Ag Junginiai ir kompozicijos, skirti parazitinių ligų gydymui
CN108495853A (zh) * 2016-01-21 2018-09-04 诺华股份有限公司 用于治疗隐孢子虫病的化合物和组合物
GB201700692D0 (en) 2017-01-16 2017-03-01 Salvensis Novel compounds and their use in the treatment of schistosomiasis

Also Published As

Publication number Publication date
AR123766A1 (es) 2023-01-11
MX2023004435A (es) 2023-05-08
UY39466A (es) 2022-05-31
TW202229277A (zh) 2022-08-01
CN116368137A (zh) 2023-06-30
WO2022079616A1 (en) 2022-04-21
US20220112189A1 (en) 2022-04-14
PY2189412A (es) 2022-05-17
US12018024B2 (en) 2024-06-25
JP2023545452A (ja) 2023-10-30
EP4229055A1 (en) 2023-08-23
EP4229055B1 (en) 2026-03-04
JP7791184B2 (ja) 2025-12-23
AU2021362803A1 (en) 2023-06-01

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