JP7791184B2 - クリプトスポリジウム症の治療のための化合物及び組成物 - Google Patents

クリプトスポリジウム症の治療のための化合物及び組成物

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Publication number
JP7791184B2
JP7791184B2 JP2023522570A JP2023522570A JP7791184B2 JP 7791184 B2 JP7791184 B2 JP 7791184B2 JP 2023522570 A JP2023522570 A JP 2023522570A JP 2023522570 A JP2023522570 A JP 2023522570A JP 7791184 B2 JP7791184 B2 JP 7791184B2
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JP
Japan
Prior art keywords
pyridine
carboxamido
methyl
carbamoylphenyl
chlorobenzoate
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JP2023522570A
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English (en)
Japanese (ja)
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JP2023545452A5 (https=
JP2023545452A (ja
Inventor
マイケル ヤング，ジョセフ
ロバート ターナー，マイケル
リュ，ペイチャオ
Original Assignee
ノバルティス アーゲー
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Publication of JP2023545452A publication Critical patent/JP2023545452A/ja
Publication of JP2023545452A5 publication Critical patent/JP2023545452A5/ja
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2023522570A 2020-10-14 2021-10-12 クリプトスポリジウム症の治療のための化合物及び組成物 Active JP7791184B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063091866P 2020-10-14 2020-10-14
US63/091,866 2020-10-14
PCT/IB2021/059376 WO2022079616A1 (en) 2020-10-14 2021-10-12 Compounds and compositions for the treatment of cryptosporidiosis

Publications (3)

Publication Number Publication Date
JP2023545452A JP2023545452A (ja) 2023-10-30
JP2023545452A5 JP2023545452A5 (https=) 2024-10-01
JP7791184B2 true JP7791184B2 (ja) 2025-12-23

Family

ID=78302850

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023522570A Active JP7791184B2 (ja) 2020-10-14 2021-10-12 クリプトスポリジウム症の治療のための化合物及び組成物

Country Status (12)

Country Link
US (1) US12018024B2 (https=)
EP (1) EP4229055B1 (https=)
JP (1) JP7791184B2 (https=)
CN (1) CN116368137A (https=)
AR (1) AR123766A1 (https=)
AU (1) AU2021362803A1 (https=)
CA (1) CA3197199A1 (https=)
MX (1) MX2023004435A (https=)
PY (1) PY2189412A (https=)
TW (1) TW202229277A (https=)
UY (1) UY39466A (https=)
WO (1) WO2022079616A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR132352A1 (es) * 2023-04-13 2025-06-18 Syngenta Crop Protection Ag Derivados de imidazo[1,2-a]pirazina

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016505529A (ja) 2012-11-19 2016-02-25 アイアールエム・リミテッド・ライアビリティ・カンパニーＩｒｍ，Ｌｌｃ 寄生虫病の処置のための化合物および組成物
JP2019507122A (ja) 2016-01-21 2019-03-14 ノバルティス アーゲー クリプトスポリジウム症の治療のための化合物および組成物
JP2020506172A (ja) 2017-01-16 2020-02-27 メルク、パテント、ゲゼルシャフト、ミット、ベシュレンクテル、ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ ＧｍｂＨ 化合物及び住血吸虫症の治療におけるそれらの使用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016505529A (ja) 2012-11-19 2016-02-25 アイアールエム・リミテッド・ライアビリティ・カンパニーＩｒｍ，Ｌｌｃ 寄生虫病の処置のための化合物および組成物
JP2019507122A (ja) 2016-01-21 2019-03-14 ノバルティス アーゲー クリプトスポリジウム症の治療のための化合物および組成物
JP2020506172A (ja) 2017-01-16 2020-02-27 メルク、パテント、ゲゼルシャフト、ミット、ベシュレンクテル、ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ ＧｍｂＨ 化合物及び住血吸虫症の治療におけるそれらの使用

Also Published As

Publication number Publication date
AR123766A1 (es) 2023-01-11
MX2023004435A (es) 2023-05-08
UY39466A (es) 2022-05-31
TW202229277A (zh) 2022-08-01
CN116368137A (zh) 2023-06-30
WO2022079616A1 (en) 2022-04-21
US20220112189A1 (en) 2022-04-14
PY2189412A (es) 2022-05-17
US12018024B2 (en) 2024-06-25
CA3197199A1 (en) 2022-04-21
JP2023545452A (ja) 2023-10-30
EP4229055A1 (en) 2023-08-23
EP4229055B1 (en) 2026-03-04
AU2021362803A1 (en) 2023-06-01

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