CA3153480A1 - Characterization of particles in solution - Google Patents
Characterization of particles in solution Download PDFInfo
- Publication number
- CA3153480A1 CA3153480A1 CA3153480A CA3153480A CA3153480A1 CA 3153480 A1 CA3153480 A1 CA 3153480A1 CA 3153480 A CA3153480 A CA 3153480A CA 3153480 A CA3153480 A CA 3153480A CA 3153480 A1 CA3153480 A1 CA 3153480A1
- Authority
- CA
- Canada
- Prior art keywords
- vessel
- particles
- measurement
- light
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N15/0205—Investigating particle size or size distribution by optical means
- G01N15/0211—Investigating a scatter or diffraction pattern
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
- G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N2015/0038—Investigating nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N2015/0092—Monitoring flocculation or agglomeration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/019—Biological contaminants; Fouling
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N15/0205—Investigating particle size or size distribution by optical means
- G01N15/0211—Investigating a scatter or diffraction pattern
- G01N2015/0222—Investigating a scatter or diffraction pattern from dynamic light scattering, e.g. photon correlation spectroscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Optical Measuring Cells (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19208187 | 2019-11-08 | ||
| EP19208187.5 | 2019-11-08 | ||
| EP20197910 | 2020-09-23 | ||
| EP20197910.1 | 2020-09-23 | ||
| PCT/EP2020/081370 WO2021089834A1 (en) | 2019-11-08 | 2020-11-06 | Characterization of particles in solution |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3153480A1 true CA3153480A1 (en) | 2021-05-14 |
Family
ID=73040120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3153480A Pending CA3153480A1 (en) | 2019-11-08 | 2020-11-06 | Characterization of particles in solution |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220404284A1 (https=) |
| EP (2) | EP4055366B1 (https=) |
| JP (2) | JP2023501942A (https=) |
| KR (2) | KR102891303B1 (https=) |
| CN (2) | CN114930151A (https=) |
| AU (2) | AU2020379227B2 (https=) |
| CA (1) | CA3153480A1 (https=) |
| WO (2) | WO2021089834A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7658575B2 (ja) | 2021-09-09 | 2025-04-08 | 国立大学法人東京農工大学 | 生体試料中のミスフォールディングタンパク質検出方法 |
| EP4328569A1 (en) * | 2022-08-23 | 2024-02-28 | NanoTemper Technologies GmbH | Measuring high protein concentrations |
| CN116735436A (zh) * | 2023-06-27 | 2023-09-12 | 沈阳农业大学 | 一种zeta电位快速测定土壤胶体临界聚沉浓度的方法 |
| EP4654117A1 (en) * | 2024-05-20 | 2025-11-26 | Malvern Panalytical Limited | Material characterisation trend analysis |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05506928A (ja) * | 1990-04-23 | 1993-10-07 | ソリッド ステイト ファームズ インコーポレイテッド | 沈降式血液分析装置および方法 |
| US5328822A (en) * | 1990-04-23 | 1994-07-12 | Solid State Farms, Inc. | Apparatus and method for sedimentation based blood analysis |
| US5973779A (en) * | 1996-03-29 | 1999-10-26 | Ansari; Rafat R. | Fiber-optic imaging probe |
| WO2003071269A2 (en) * | 2002-02-20 | 2003-08-28 | Affinium Pharmaceuticals, Inc. | Methods and apparatuses for characterizing stability of biological molecules |
| FR2856792B1 (fr) * | 2003-06-27 | 2006-09-15 | Commissariat Energie Atomique | Procede et dispositif de dosage d'un echantillon biologique ou chimique |
| EP1704402B1 (en) * | 2004-01-14 | 2016-05-11 | Luminex Corporation | Methods and systems for dynamic range expansion |
| DE102004005878A1 (de) * | 2004-02-05 | 2005-09-01 | Rina-Netzwerk Rna Technologien Gmbh | Verfahren zur Überwachung der Herstellung von Biomolekülkristallen |
| EP2115424B1 (en) * | 2007-02-02 | 2018-10-24 | Canadian Blood Services | Method of detecting bacterial contamination using dynamic light scattering |
| US8817244B2 (en) * | 2010-01-15 | 2014-08-26 | Mitsui Engineering & Shipbuilding Co., Ltd. | Fluorescence measurement device and fluorescence measurement method |
| DE102010005962B4 (de) * | 2010-01-21 | 2012-01-26 | Alv-Laser Vertriebsgesellschaft Mbh | Verfahren zur Bestimmung der statischen und/oder dynamischen Lichtstreuung |
| DE102011055330B4 (de) * | 2011-11-14 | 2024-10-31 | Leica Microsystems Cms Gmbh | Verfahren zum Messen der Lebensdauer eines angeregten Zustandes in einer Probe |
| GB201415783D0 (en) * | 2014-09-05 | 2014-10-22 | Malvern Instr Ltd | Particle characterisation |
| DE102014018535A1 (de) * | 2014-12-12 | 2016-06-16 | Nanotemper Technologies Gmbh | System und Verfahren für ein abdichtungsfreies Temperieren von Kapillaren |
| KR20170013768A (ko) * | 2015-07-28 | 2017-02-07 | 울산과학기술원 | 라만 센서 및 라만 분석 방법 |
| EP4242304A3 (en) * | 2015-10-01 | 2024-02-07 | Revolution Medicines, Inc. | Methods and reagents for analyzing protein-protein interfaces |
| LT3150988T (lt) * | 2015-10-01 | 2021-06-25 | Nanotemper Technologies Gmbh | Dalelių stabilumo ir agregacijos optinio matavimo sistema bei būdas |
| EP3159674A1 (en) * | 2015-10-19 | 2017-04-26 | European Molecular Biology Laboratory | Measurement cell for saxs measurements and for dls measurements |
| US9554738B1 (en) * | 2016-03-30 | 2017-01-31 | Zyomed Corp. | Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing |
| KR101934926B1 (ko) * | 2017-01-10 | 2019-01-03 | 충남대학교산학협력단 | 유동 유체 내의 나노입자 거동 예측 방법 및 장치 |
| US10473591B2 (en) * | 2017-05-01 | 2019-11-12 | Wyatt Technology Corporation | High throughput method and apparatus for measuring multiple optical properties of a liquid sample |
| CN107782643A (zh) * | 2017-09-27 | 2018-03-09 | 华中科技大学 | 一种高浓度颗粒群的光纤动态光散射检测方法 |
| CA3089230A1 (en) * | 2018-03-02 | 2019-09-06 | Cdr-Life Ag | Trispecific antigen binding proteins |
| US20210379186A1 (en) * | 2018-04-16 | 2021-12-09 | Merck Patent Gmbh | Additives for protein formulations to improve thermal stability |
| CN108983252B (zh) * | 2018-07-30 | 2022-08-26 | 武汉舒博光电技术有限公司 | 双光束超分辨定位系统及方法 |
-
2020
- 2020-11-06 JP JP2022525257A patent/JP2023501942A/ja active Pending
- 2020-11-06 AU AU2020379227A patent/AU2020379227B2/en active Active
- 2020-11-06 KR KR1020227019316A patent/KR102891303B1/ko active Active
- 2020-11-06 EP EP20800668.4A patent/EP4055366B1/en active Active
- 2020-11-06 CN CN202080092388.6A patent/CN114930151A/zh active Pending
- 2020-11-06 EP EP20800216.2A patent/EP4055365B1/en active Active
- 2020-11-06 AU AU2020378640A patent/AU2020378640A1/en not_active Abandoned
- 2020-11-06 WO PCT/EP2020/081370 patent/WO2021089834A1/en not_active Ceased
- 2020-11-06 KR KR1020227019318A patent/KR20220093215A/ko active Pending
- 2020-11-06 JP JP2022525259A patent/JP7461078B2/ja active Active
- 2020-11-06 US US17/775,400 patent/US20220404284A1/en not_active Abandoned
- 2020-11-06 WO PCT/EP2020/081378 patent/WO2021089841A1/en not_active Ceased
- 2020-11-06 CA CA3153480A patent/CA3153480A1/en active Pending
- 2020-11-06 CN CN202080092390.3A patent/CN114930152B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN114930152B (zh) | 2026-04-03 |
| EP4055365A1 (en) | 2022-09-14 |
| AU2020378640A1 (en) | 2022-04-28 |
| AU2020379227A1 (en) | 2022-04-21 |
| KR20220092620A (ko) | 2022-07-01 |
| JP2023500642A (ja) | 2023-01-10 |
| EP4055365B1 (en) | 2026-01-21 |
| WO2021089834A1 (en) | 2021-05-14 |
| WO2021089841A1 (en) | 2021-05-14 |
| EP4055366C0 (en) | 2026-02-18 |
| JP7461078B2 (ja) | 2024-04-03 |
| KR102891303B1 (ko) | 2025-11-26 |
| EP4055366A1 (en) | 2022-09-14 |
| CN114930151A (zh) | 2022-08-19 |
| WO2021089841A9 (en) | 2022-06-30 |
| KR20220093215A (ko) | 2022-07-05 |
| EP4055366B1 (en) | 2026-02-18 |
| US20220373557A1 (en) | 2022-11-24 |
| JP2023501942A (ja) | 2023-01-20 |
| US20220404284A1 (en) | 2022-12-22 |
| EP4055365C0 (en) | 2026-01-21 |
| CN114930152A (zh) | 2022-08-19 |
| AU2020379227B2 (en) | 2025-11-06 |
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Legal Events
| Date | Code | Title | Description |
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| EEER | Examination request |
Effective date: 20220809 |
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