CA3104676A1 - Compounds and methods for reducing lrrk2 expression - Google Patents
Compounds and methods for reducing lrrk2 expression Download PDFInfo
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- CA3104676A1 CA3104676A1 CA3104676A CA3104676A CA3104676A1 CA 3104676 A1 CA3104676 A1 CA 3104676A1 CA 3104676 A CA3104676 A CA 3104676A CA 3104676 A CA3104676 A CA 3104676A CA 3104676 A1 CA3104676 A1 CA 3104676A1
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Classifications
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- C12N2310/30—Chemical structure
- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/346—Spatial arrangement of the modifications having a combination of backbone and sugar modifications
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/352—Nature of the modification linked to the nucleic acid via a carbon atom
- C12N2310/3525—MOE, methoxyethoxy
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- C12N2320/00—Applications; Uses
- C12N2320/10—Applications; Uses in screening processes
- C12N2320/11—Applications; Uses in screening processes for the determination of target sites, i.e. of active nucleic acids
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| WO2021224320A1 (en) | 2020-05-06 | 2021-11-11 | Les Laboratoires Servier | New macrocyclic lrrk2 kinase inhibitors |
| UY39344A (es) * | 2020-07-28 | 2022-02-25 | Ionis Pharmaceuticals Inc | Compuestos y métodos para reducir la expresión de app |
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