CA3094329A1 - Methods and compositions comprising tumor suppressor gene therapy and cd122/cd132 agonists for the treatment of cancer - Google Patents

Methods and compositions comprising tumor suppressor gene therapy and cd122/cd132 agonists for the treatment of cancer Download PDF

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Publication number
CA3094329A1
CA3094329A1 CA3094329A CA3094329A CA3094329A1 CA 3094329 A1 CA3094329 A1 CA 3094329A1 CA 3094329 A CA3094329 A CA 3094329A CA 3094329 A CA3094329 A CA 3094329A CA 3094329 A1 CA3094329 A1 CA 3094329A1
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Prior art keywords
virus
inhibitor
antibody
nucleic acid
agonist
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CA3094329A
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English (en)
French (fr)
Inventor
Robert E. Sobol
Kerstin B. Menander
Dora WIEDERHOLD
Sunil Chada
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Multivir Inc
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Multivir Inc
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    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
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    • A61K35/66—Microorganisms or materials therefrom
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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CA3094329A 2018-03-19 2019-03-19 Methods and compositions comprising tumor suppressor gene therapy and cd122/cd132 agonists for the treatment of cancer Pending CA3094329A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862645022P 2018-03-19 2018-03-19
US62/645,022 2018-03-19
US201962803887P 2019-02-11 2019-02-11
US62/803,887 2019-02-11
PCT/US2019/022985 WO2020036635A2 (en) 2018-03-19 2019-03-19 Methods and compositions comprising tumor suppressor gene therapy and cd122/cd132 agonists for the treatment of cancer

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CA3094329A1 true CA3094329A1 (en) 2020-02-20

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CA3094329A Pending CA3094329A1 (en) 2018-03-19 2019-03-19 Methods and compositions comprising tumor suppressor gene therapy and cd122/cd132 agonists for the treatment of cancer

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US (2) US12454561B2 (enExample)
EP (1) EP3768698B1 (enExample)
JP (2) JP7849143B2 (enExample)
KR (2) KR20260082357A (enExample)
CN (1) CN112020510B (enExample)
AU (1) AU2019322487B2 (enExample)
CA (1) CA3094329A1 (enExample)
WO (1) WO2020036635A2 (enExample)

Cited By (1)

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WO2021211857A1 (en) * 2020-04-15 2021-10-21 Alkermes Pharma Ireland Limited Immunostimulatory agents in combination with angiogenesis inhibitors

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EP4178586A4 (en) * 2020-07-09 2024-10-09 Shanghai Institute of Materia Medica, Chinese Academy of Sciences Compositions and methods for inhibiting ythdf1
WO2022140776A1 (en) * 2020-12-21 2022-06-30 Multivir Inc. Methods and compositions comprising tumor suppressor gene therapy for the inhibition of pathogens
CN113368246B (zh) * 2021-05-12 2023-05-26 中山大学 一种增效的抗肿瘤药物
EP4373505A1 (en) * 2021-07-19 2024-05-29 Regeneron Pharmaceuticals, Inc. Combination of checkpoint inhibitors and an oncolytic virus for treating cancer
CN115287299B (zh) * 2021-12-29 2023-12-29 浙江理工大学 一种重组溶瘤痘苗病毒的构建方法及其应用
CN118871467A (zh) 2022-03-04 2024-10-29 抗衰老治疗公司 抗pd-l2抗体
WO2024196963A2 (en) * 2023-03-21 2024-09-26 The Regents Of The University Of California Compositions and methods for genome editing
CN116789828B (zh) * 2023-05-31 2023-11-17 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) 一种抗cd132的单克隆抗体及其应用
CN117700554B (zh) * 2023-08-03 2024-07-12 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) 一种抗人源cd132的单克隆抗体及其应用
WO2025226592A1 (en) * 2024-04-22 2025-10-30 The Johns Hopkins University Cytotoxic synergy of crispr-cas9 with dna damage repair inhibitors
CN118697886A (zh) * 2024-05-31 2024-09-27 中南大学湘雅三医院 一种药物组合物及其应用

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