CA3091468A1 - Utilisation d'anticorps anti-sirpa v1 humains et procede de production d'anticorps anti-sirpa v1 - Google Patents
Utilisation d'anticorps anti-sirpa v1 humains et procede de production d'anticorps anti-sirpa v1 Download PDFInfo
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K—PEPTIDES
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
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Abstract
L'invention se rapporte au domaine de l'immunothérapie. La présente invention concerne des anticorps utiles dans des applications thérapeutiques et diagnostiques ciblant SIRPa humain, lesdits anticorps améliorant la présentation croisée d'antigènes à des lymphocytes T. L'invention concerne également des anticorps dirigés contre des isoformes spécifiques de SIRPa et sont capables de perturber l'interaction entre ces isoformes de SIRPa et CD47 humain pour une utilisation dans le traitement ou la prévention d'une maladie, ou dans des applications diagnostiques, et des procédés de production et/ou de sélection d'anticorps anti-SIRPa humains qui se lient avec des affinités différentes à plusieurs isoformes d'éléments SIRP humains.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18305271.1 | 2018-03-13 | ||
| EP18305271 | 2018-03-13 | ||
| PCT/EP2019/056250 WO2019175218A1 (fr) | 2018-03-13 | 2019-03-13 | Utilisation d'anticorps anti-sirpa v1 humains et procédé de production d'anticorps anti-sirpa v1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3091468A1 true CA3091468A1 (fr) | 2019-09-19 |
Family
ID=61972458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3091468A Pending CA3091468A1 (fr) | 2018-03-13 | 2019-03-13 | Utilisation d'anticorps anti-sirpa v1 humains et procede de production d'anticorps anti-sirpa v1 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11884723B2 (fr) |
| EP (1) | EP3765512A1 (fr) |
| JP (1) | JP2021517130A (fr) |
| KR (1) | KR20210006338A (fr) |
| CN (1) | CN112105646A (fr) |
| AU (1) | AU2019233577A1 (fr) |
| BR (1) | BR112020017709A2 (fr) |
| CA (1) | CA3091468A1 (fr) |
| CL (1) | CL2020002305A1 (fr) |
| EA (1) | EA202091859A1 (fr) |
| MX (1) | MX2020009121A (fr) |
| PH (1) | PH12020551491A1 (fr) |
| WO (1) | WO2019175218A1 (fr) |
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| KR102355240B1 (ko) | 2016-04-14 | 2022-01-25 | 오제 이뮈노테라프틱스 | 신규한 항-SIRPa 항체 및 이들의 치료학적 적용 방법 |
| CN115317603A (zh) | 2016-07-07 | 2022-11-11 | 小利兰·斯坦福大学托管委员会 | 抗体佐剂缀合物 |
| CN110325549B (zh) | 2016-12-09 | 2024-03-08 | 艾利妥 | 抗SIRPα抗体及其使用方法 |
| WO2019073080A1 (fr) | 2017-10-13 | 2019-04-18 | Ose Immunotherapeutics | Anticorps anti-sirpa modifiés et leurs utilisations |
| WO2019226973A1 (fr) | 2018-05-25 | 2019-11-28 | Alector Llc | Anticorps anti-sirpa et leurs procédés d'utilisation |
| KR20220004634A (ko) | 2019-03-15 | 2022-01-11 | 볼트 바이오테라퓨틱스 인코퍼레이티드 | Her2를 표적으로 하는 면역접합체 |
| BR112021026376A2 (pt) | 2019-06-25 | 2022-05-10 | Gilead Sciences Inc | Proteínas de fusão flt3l-fc e métodos de uso |
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| MX2022005123A (es) | 2019-10-31 | 2022-05-30 | Forty Seven Inc | Tratamiento basado en anti-cd47 y anti-cd20 para cancer hematologico. |
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| CN111635458A (zh) * | 2020-03-20 | 2020-09-08 | 上海健信生物医药科技有限公司 | 靶向Sirpα的抗体或其抗原结合片段及其制备和应用 |
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| WO2022245671A1 (fr) | 2021-05-18 | 2022-11-24 | Gilead Sciences, Inc. | Méthodes d'utilisation de protéines de fusion flt3l-fc |
| CN117355531A (zh) | 2021-06-23 | 2024-01-05 | 吉利德科学公司 | 二酰基甘油激酶调节化合物 |
| CN117396478A (zh) | 2021-06-23 | 2024-01-12 | 吉利德科学公司 | 二酰基甘油激酶调节化合物 |
| EP4359389A1 (fr) | 2021-06-23 | 2024-05-01 | Gilead Sciences, Inc. | Composés de modulation de la diacylglycérol kinase |
| EP4359411A1 (fr) | 2021-06-23 | 2024-05-01 | Gilead Sciences, Inc. | Composés modulant les diacylglycérol kinases |
| CA3221281A1 (fr) | 2021-06-29 | 2023-01-05 | Seagen Inc. | Methodes de traitement du cancer au moyen d'une combinaison d'un anticorps anti-cd70 non fucosyle et d'un antagoniste de cd47 |
| CN113583979B (zh) * | 2021-08-03 | 2022-11-22 | 杭州荣谷生物科技有限公司 | 一种重组溶瘤痘苗病毒、制备方法及其用途 |
| TW202330504A (zh) | 2021-10-28 | 2023-08-01 | 美商基利科學股份有限公司 | 嗒𠯤—３（２ｈ）—酮衍生物 |
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| EP3012271A1 (fr) | 2014-10-24 | 2016-04-27 | Effimune | Procédé et compositions pour induire la différenciation de cellule suppressives dérivées de myéloïde pour traiter le cancer et les maladies infectieuses |
| EP4186927A1 (fr) | 2015-10-21 | 2023-05-31 | Ose Immunotherapeutics | Procédés et compositions de modification de la polarisation des macrophages en cellules pro-inflammatoires pour traiter le cancer |
| KR102355240B1 (ko) | 2016-04-14 | 2022-01-25 | 오제 이뮈노테라프틱스 | 신규한 항-SIRPa 항체 및 이들의 치료학적 적용 방법 |
| WO2017178653A2 (fr) | 2016-04-14 | 2017-10-19 | Ose Immunotherapeutics | Nouveaux anticorps anti-sirpa et leurs applications thérapeutiques |
| WO2019073080A1 (fr) | 2017-10-13 | 2019-04-18 | Ose Immunotherapeutics | Anticorps anti-sirpa modifiés et leurs utilisations |
-
2019
- 2019-03-13 BR BR112020017709-1A patent/BR112020017709A2/pt not_active IP Right Cessation
- 2019-03-13 US US16/979,627 patent/US11884723B2/en active Active
- 2019-03-13 EA EA202091859A patent/EA202091859A1/ru unknown
- 2019-03-13 JP JP2020546939A patent/JP2021517130A/ja active Pending
- 2019-03-13 WO PCT/EP2019/056250 patent/WO2019175218A1/fr unknown
- 2019-03-13 MX MX2020009121A patent/MX2020009121A/es unknown
- 2019-03-13 KR KR1020207029293A patent/KR20210006338A/ko unknown
- 2019-03-13 CA CA3091468A patent/CA3091468A1/fr active Pending
- 2019-03-13 EP EP19711862.3A patent/EP3765512A1/fr active Pending
- 2019-03-13 CN CN201980031527.1A patent/CN112105646A/zh active Pending
- 2019-03-13 AU AU2019233577A patent/AU2019233577A1/en not_active Abandoned
-
2020
- 2020-09-07 CL CL2020002305A patent/CL2020002305A1/es unknown
- 2020-09-16 PH PH12020551491A patent/PH12020551491A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021517130A (ja) | 2021-07-15 |
| PH12020551491A1 (en) | 2021-09-06 |
| CN112105646A (zh) | 2020-12-18 |
| KR20210006338A (ko) | 2021-01-18 |
| BR112020017709A2 (pt) | 2020-12-29 |
| MX2020009121A (es) | 2020-10-01 |
| US20210040206A1 (en) | 2021-02-11 |
| EP3765512A1 (fr) | 2021-01-20 |
| EA202091859A1 (ru) | 2021-02-04 |
| AU2019233577A1 (en) | 2020-09-03 |
| CL2020002305A1 (es) | 2021-02-12 |
| US11884723B2 (en) | 2024-01-30 |
| WO2019175218A1 (fr) | 2019-09-19 |
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