CA3073964A1 - Glucagon-like peptide 1 receptor agonists and uses thereof - Google Patents
Glucagon-like peptide 1 receptor agonists and uses thereof Download PDFInfo
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- CA3073964A1 CA3073964A1 CA3073964A CA3073964A CA3073964A1 CA 3073964 A1 CA3073964 A1 CA 3073964A1 CA 3073964 A CA3073964 A CA 3073964A CA 3073964 A CA3073964 A CA 3073964A CA 3073964 A1 CA3073964 A1 CA 3073964A1
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- glp1
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- C12N15/09—Recombinant DNA-technology
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| IL273253B2 (en) * | 2017-09-22 | 2024-07-01 | Regeneron Pharma | Glucagon-like peptide-1 receptor agonists and their uses |
| US12122817B2 (en) * | 2020-09-22 | 2024-10-22 | Serpentide Inc. | Long-lasting GLP1 analogue drug for type-2 diabetes |
| WO2022117044A1 (en) * | 2020-12-03 | 2022-06-09 | Sunshine Lake Pharma Co., Ltd. | Glp-1/gcg dual receptor agonist polypeptide and fusion protein thereof |
| KR102828488B1 (ko) * | 2020-12-03 | 2025-07-02 | 이뮤노포지 주식회사 | Glp-1 수용체 작용제 및 항-오스카 항체를 포함하는 융합 단백질 및 이의 용도 |
| CN112716966B (zh) * | 2021-02-03 | 2022-05-03 | 浙江诺得药业有限公司 | 一种恩格列净药用组合物及其制备方法 |
| CN113461785B (zh) * | 2021-04-13 | 2022-10-14 | 湖南中晟全肽生化有限公司 | Glp-1受体激动剂及其应用 |
| CN119638849A (zh) * | 2021-10-18 | 2025-03-18 | 深圳科兴药业有限公司 | 一种生长激素融合蛋白及其应用 |
| CN114788876B (zh) * | 2022-02-24 | 2024-07-05 | 北京医院 | 治疗糖尿病的mRNA药物制剂及其制备方法与应用 |
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| US8257740B1 (en) | 2011-08-15 | 2012-09-04 | Gp Medical, Inc. | Pharmaceutical composition of nanoparticles |
| US20060275288A1 (en) | 2005-01-20 | 2006-12-07 | Grihalde Nelson D | GLP-1 receptor agonist and allosteric modulator monoclonal antibodies and uses thereof |
| US8246995B2 (en) | 2005-05-10 | 2012-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells |
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| ES2620610T3 (es) | 2008-12-10 | 2017-06-29 | Glaxosmithkline Llc | Composiciones farmacéuticas de albiglutide |
| US20120148586A1 (en) | 2009-08-27 | 2012-06-14 | Joyce Ching Tsu Chou | Glucagon-like protein-1 receptor (glp-1r) agonists for treating autoimmune disorders |
| KR101229610B1 (ko) | 2009-10-09 | 2013-02-05 | 한남대학교 산학협력단 | Ｇｌｐ-1 유사체의 융합체, 및 이를 유효성분으로 함유하는 당뇨병의 예방 또는 치료용 조성물 |
| JP5774595B2 (ja) | 2009-10-28 | 2015-09-09 | ヤンセン バイオテツク，インコーポレーテツド | 抗ｇｌｐ−１ｒ抗体及びそれらの使用 |
| US20120294855A1 (en) | 2009-11-03 | 2012-11-22 | Eli Lilly & Company | Glp-1 receptor agonist compounds for obstructive sleep apnea |
| EP2892919A1 (en) | 2012-09-07 | 2015-07-15 | Sanofi | Fusion proteins for treating a metabolic syndrome |
| KR102165434B1 (ko) | 2013-01-17 | 2020-10-14 | 브이티브이 테라퓨틱스 엘엘씨 | 2형 당뇨병 및 다른 장애의 치료를 위한 glp1r 작용제 및 메트포민의 조합 및 이것들의 사용법 |
| US20150259416A1 (en) | 2014-03-12 | 2015-09-17 | Biocrine Ab | Methods for treating and/or limiting development of diabetes |
| CN104371019B (zh) * | 2013-08-13 | 2019-09-10 | 鸿运华宁（杭州）生物医药有限公司 | 一种能与glp-1r特异性结合的抗体及其与glp-1的融合蛋白质 |
| CN104098702B (zh) * | 2014-07-23 | 2017-06-16 | 湖北工业大学 | 一种利用mfh融合蛋白制备glp‑1多肽或其类似物方法和应用 |
| CN106390100B (zh) * | 2015-01-28 | 2021-06-22 | 中国科学院天津工业生物技术研究所 | 一种多肽复合物作为glp-1药物载体的应用、方法及其融合蛋白复合物 |
| JP6731953B2 (ja) | 2015-02-11 | 2020-07-29 | ジーエムエーエックス バイオファーム エルエルシー． | Ｇｌｐ−１ｒ抗体融合タンパク質の安定な医薬溶液製剤 |
| TWI622596B (zh) | 2015-10-26 | 2018-05-01 | 美國禮來大藥廠 | 升糖素受體促效劑 |
| BR112018072968A2 (pt) * | 2016-06-09 | 2019-02-19 | Medimmune Limited | peptídeos monolipidados resistentes às proteases |
| IL273253B2 (en) * | 2017-09-22 | 2024-07-01 | Regeneron Pharma | Glucagon-like peptide-1 receptor agonists and their uses |
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