CA3072282A1 - Nanoemulsion of iodinated fatty acids for ct imaging - Google Patents

Nanoemulsion of iodinated fatty acids for ct imaging Download PDF

Info

Publication number
CA3072282A1
CA3072282A1 CA3072282A CA3072282A CA3072282A1 CA 3072282 A1 CA3072282 A1 CA 3072282A1 CA 3072282 A CA3072282 A CA 3072282A CA 3072282 A CA3072282 A CA 3072282A CA 3072282 A1 CA3072282 A1 CA 3072282A1
Authority
CA
Canada
Prior art keywords
contrast agent
emulsion
vivo imaging
nano
fatty acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3072282A
Other languages
English (en)
French (fr)
Inventor
Laurent Vinet
Andrej Babic
Eric Allemann
Original Assignee
Universite de Geneve
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite de Geneve filed Critical Universite de Geneve
Publication of CA3072282A1 publication Critical patent/CA3072282A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Medicinal Preparation (AREA)
CA3072282A 2017-08-07 2018-07-27 Nanoemulsion of iodinated fatty acids for ct imaging Pending CA3072282A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17185185.0 2017-08-07
EP17185185 2017-08-07
PCT/EP2018/070501 WO2019030024A1 (en) 2017-08-07 2018-07-27 NANOEMULSION OF IODIZED FATTY ACIDS FOR COMPUTER-ASSISTED TOMOGRAPHY (CT) IMAGING

Publications (1)

Publication Number Publication Date
CA3072282A1 true CA3072282A1 (en) 2019-02-14

Family

ID=59564118

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3072282A Pending CA3072282A1 (en) 2017-08-07 2018-07-27 Nanoemulsion of iodinated fatty acids for ct imaging

Country Status (9)

Country Link
US (1) US11654202B2 (https=)
EP (1) EP3664855A1 (https=)
JP (1) JP7210542B2 (https=)
CN (1) CN111194225B (https=)
AU (1) AU2018314406B2 (https=)
BR (1) BR112020002619A2 (https=)
CA (1) CA3072282A1 (https=)
EA (1) EA202090139A1 (https=)
WO (1) WO2019030024A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118178688A (zh) 2019-02-13 2024-06-14 日内瓦大学 用于恶病质的检测的ct造影剂
CA3190518A1 (en) * 2020-08-06 2022-02-10 Adiposs SA Pet-ct imaging methods, contrast agents and pharmaceutical compositions for use in said imaging methods
CN112933246A (zh) * 2020-12-17 2021-06-11 太阳雨林（厦门）生物医药有限公司 一种可显影的油制剂及其制备方法
JP2024530159A (ja) * 2021-08-02 2024-08-16 マイクロベンション インコーポレイテッド 医療画像用ヨウ素化脂肪酸
WO2023073195A1 (en) 2021-10-28 2023-05-04 Adiposs SA Emulsions, compositions for emulsions, methods for making the same and uses thereof
WO2025079088A1 (en) * 2023-10-11 2025-04-17 Bioroot Exploration India Private Limited A contrast agent for computed tomography and process of preparation thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5258172A (en) * 1983-12-29 1993-11-02 Rubin Daniel L Iodinated aliphatic emulsions for X-ray contrast
ATE89171T1 (de) 1987-06-11 1993-05-15 Kabi Pharmacia Ab Jod enthaltende emulsion.
US5861367A (en) 1993-08-04 1999-01-19 Colgate Palmolive Company Cleaning and disinfecting composition in microemulsion/liquid crystal form comprising aldehyde and mixture of partially esterified, fully esterified and non-esterified polyhydric alcohols
FR2736549B1 (fr) * 1995-07-11 1997-10-10 Louis Jung Esters d'acides gras iodes, acides gras iodes et leurs derives, obtenus par iodohydrination faisant intervenir des derives alkylsilyles avec des iodures alcalins et leurs activites pharmacologiques
DE19936727A1 (de) 1999-08-06 2001-02-08 Henkel Kgaa Niotensidbasiertes wäßriges mehrphasiges Reinigungsmittel
CA2534426A1 (en) * 2003-08-08 2005-02-17 Barnes-Jewish Hospital Emulsion particles for imaging and therapy and methods of use thereof
GB0408684D0 (en) 2004-04-19 2004-05-19 Guy S And St Thomas Hospital N Diagnostic method
SG10201505948VA (en) 2004-12-13 2015-09-29 Amylin Pharmaceuticals Llc Pancreatic Polypeptide Family Motifs, Polypeptides And Methods Comprising The Same
EP1989179B1 (en) 2006-02-15 2011-01-26 Ge Healthcare As Contrast agents
US20080319315A1 (en) 2007-06-07 2008-12-25 Beth Israel Deaconess Medical Center Method of reducing interferences in positron emission tomography
WO2012080279A1 (en) 2010-12-17 2012-06-21 Universite De Strasbourg Radiopaque iodinated products intended for use medical imaging and their methods of preparation
KR101263733B1 (ko) 2011-03-22 2013-05-14 한국과학기술연구원 리피오돌을 함유하는 컴퓨터 단층촬영용 혈관 조영제
CN102166365B (zh) 2011-04-25 2012-10-24 东南大学 一种多模态碘油纳米乳造影剂的制备方法
DE102012204378A1 (de) 2012-03-20 2013-09-26 Bernd Schwegmann Gmbh & Co. Kg Reinigungsmittel auf Mikroemulsionsbasis
US10786583B2 (en) 2013-09-30 2020-09-29 B.Braun Melsungen Ag Pre-saturation of the liver and subsequent administration of the contrast agent
US10668161B2 (en) 2014-02-24 2020-06-02 The Regents Of The University Of California Therapeutic hyperbranched polyglycerol encapsulated biomolecules
US10157462B2 (en) 2016-06-27 2018-12-18 University Of Central Florida Research Foundation, Inc. System and method for image-based quantification of white and brown adipose tissue at the whole-body, organ and body-region levels

Also Published As

Publication number Publication date
US11654202B2 (en) 2023-05-23
CN111194225A (zh) 2020-05-22
WO2019030024A1 (en) 2019-02-14
EP3664855A1 (en) 2020-06-17
US20210330820A1 (en) 2021-10-28
AU2018314406B2 (en) 2024-08-15
AU2018314406A1 (en) 2020-02-20
CN111194225B (zh) 2023-01-13
JP2020529441A (ja) 2020-10-08
EA202090139A1 (ru) 2020-08-06
BR112020002619A2 (pt) 2020-07-28
JP7210542B2 (ja) 2023-01-23

Similar Documents

Publication Publication Date Title
US11654202B2 (en) Nanoemulsion of iodinated fatty acids for CT imaging
JP7522744B2 (ja) 悪液質を検出するためのｃｔ造影剤
Zhou et al. Orally administered oleoylethanolamide protects mice from focal cerebral ischemic injury by activating peroxisome proliferator-activated receptor α
JP2017141276A (ja) 腎症の処置に有用な組成物およびその調製方法
CA2893799A1 (en) Semifluorocarbon compound containing contrast agent
JP2020529441A5 (https=)
US4873075A (en) Polyiodinated triglyceride analogs as radiologic agents
US11534447B2 (en) Emulsion composition for chemoembolization and method for producing same
PT100488A (pt) Composicao alimentar contendo gliceridos
US20230284994A1 (en) Pet-ct imaging methods, contrast agents and pharmaceutical compositions for use in said imaging methods
WO2013121284A1 (en) Iodinated products intended for a use for the medical imaging and their methods of preparation
TWI679990B (zh) 肝臟之預飽和以及後續之對比劑的投予
EA043372B1 (ru) Контрастный агент для компьютерной томографии
US20140065067A1 (en) Radiopaque iodinated products intended for use medical imaging and their methods
EA045963B1 (ru) Контрастный агент для кт для детекции кахексии
PT815072E (pt) Agentes de contraste de raios x para a tomografia e a urografia computadorizadas
JP2004115378A (ja) 水溶性ヨード化合物を含むリポソーム

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20230628

D15 Examination report completed

Free format text: ST27 STATUS EVENT CODE: A-2-2-D10-D15-D126 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: EXAMINER'S REPORT

Effective date: 20240917

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT RECEIVED - RESPONSE TO EXAMINER'S REQUISITION

Effective date: 20241224

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-2-2-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT

Effective date: 20250211

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT DETERMINED COMPLIANT

Effective date: 20250616

P13 Application amended

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION AMENDED

Effective date: 20250616

MFA Maintenance fee for application paid

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 7TH ANNIV.) - STANDARD

Year of fee payment: 7

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250626

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250626

D22 Grant of ip right intended

Free format text: ST27 STATUS EVENT CODE: A-2-2-D10-D22-D128 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: ALLOWANCE REQUIREMENTS DETERMINED COMPLIANT

Effective date: 20260423

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-2-2-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20260423