AU2018314406B2 - Nanoemulsion of iodinated fatty acids for CT imaging - Google Patents

Nanoemulsion of iodinated fatty acids for CT imaging Download PDF

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Publication number
AU2018314406B2
AU2018314406B2 AU2018314406A AU2018314406A AU2018314406B2 AU 2018314406 B2 AU2018314406 B2 AU 2018314406B2 AU 2018314406 A AU2018314406 A AU 2018314406A AU 2018314406 A AU2018314406 A AU 2018314406A AU 2018314406 B2 AU2018314406 B2 AU 2018314406B2
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AU
Australia
Prior art keywords
contrast agent
emulsion
vivo imaging
fatty acids
iodinated
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Active
Application number
AU2018314406A
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English (en)
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AU2018314406A1 (en
Inventor
Eric Allemann
Andrej Babic
Laurent VINET
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Universite de Geneve
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Universite de Geneve
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Assigned to UNIVERSITÉ DE GENÈVE reassignment UNIVERSITÉ DE GENÈVE Amend patent request/document other than specification (104) Assignors: UNIVERSITY OF GENEVA
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461Dispersions, colloids, emulsions or suspensions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Medicinal Preparation (AREA)
AU2018314406A 2017-08-07 2018-07-27 Nanoemulsion of iodinated fatty acids for CT imaging Active AU2018314406B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17185185.0 2017-08-07
EP17185185 2017-08-07
PCT/EP2018/070501 WO2019030024A1 (en) 2017-08-07 2018-07-27 NANOEMULSION OF IODIZED FATTY ACIDS FOR COMPUTER-ASSISTED TOMOGRAPHY (CT) IMAGING

Publications (2)

Publication Number Publication Date
AU2018314406A1 AU2018314406A1 (en) 2020-02-20
AU2018314406B2 true AU2018314406B2 (en) 2024-08-15

Family

ID=59564118

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018314406A Active AU2018314406B2 (en) 2017-08-07 2018-07-27 Nanoemulsion of iodinated fatty acids for CT imaging

Country Status (9)

Country Link
US (1) US11654202B2 (https=)
EP (1) EP3664855A1 (https=)
JP (1) JP7210542B2 (https=)
CN (1) CN111194225B (https=)
AU (1) AU2018314406B2 (https=)
BR (1) BR112020002619A2 (https=)
CA (1) CA3072282A1 (https=)
EA (1) EA202090139A1 (https=)
WO (1) WO2019030024A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118178688A (zh) 2019-02-13 2024-06-14 日内瓦大学 用于恶病质的检测的ct造影剂
CA3190518A1 (en) * 2020-08-06 2022-02-10 Adiposs SA Pet-ct imaging methods, contrast agents and pharmaceutical compositions for use in said imaging methods
CN112933246A (zh) * 2020-12-17 2021-06-11 太阳雨林(厦门)生物医药有限公司 一种可显影的油制剂及其制备方法
JP2024530159A (ja) * 2021-08-02 2024-08-16 マイクロベンション インコーポレイテッド 医療画像用ヨウ素化脂肪酸
WO2023073195A1 (en) 2021-10-28 2023-05-04 Adiposs SA Emulsions, compositions for emulsions, methods for making the same and uses thereof
WO2025079088A1 (en) * 2023-10-11 2025-04-17 Bioroot Exploration India Private Limited A contrast agent for computed tomography and process of preparation thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5258172A (en) * 1983-12-29 1993-11-02 Rubin Daniel L Iodinated aliphatic emulsions for X-ray contrast
ATE89171T1 (de) 1987-06-11 1993-05-15 Kabi Pharmacia Ab Jod enthaltende emulsion.
US5861367A (en) 1993-08-04 1999-01-19 Colgate Palmolive Company Cleaning and disinfecting composition in microemulsion/liquid crystal form comprising aldehyde and mixture of partially esterified, fully esterified and non-esterified polyhydric alcohols
FR2736549B1 (fr) * 1995-07-11 1997-10-10 Louis Jung Esters d'acides gras iodes, acides gras iodes et leurs derives, obtenus par iodohydrination faisant intervenir des derives alkylsilyles avec des iodures alcalins et leurs activites pharmacologiques
DE19936727A1 (de) 1999-08-06 2001-02-08 Henkel Kgaa Niotensidbasiertes wäßriges mehrphasiges Reinigungsmittel
CA2534426A1 (en) * 2003-08-08 2005-02-17 Barnes-Jewish Hospital Emulsion particles for imaging and therapy and methods of use thereof
GB0408684D0 (en) 2004-04-19 2004-05-19 Guy S And St Thomas Hospital N Diagnostic method
SG10201505948VA (en) 2004-12-13 2015-09-29 Amylin Pharmaceuticals Llc Pancreatic Polypeptide Family Motifs, Polypeptides And Methods Comprising The Same
EP1989179B1 (en) 2006-02-15 2011-01-26 Ge Healthcare As Contrast agents
US20080319315A1 (en) 2007-06-07 2008-12-25 Beth Israel Deaconess Medical Center Method of reducing interferences in positron emission tomography
WO2012080279A1 (en) 2010-12-17 2012-06-21 Universite De Strasbourg Radiopaque iodinated products intended for use medical imaging and their methods of preparation
KR101263733B1 (ko) 2011-03-22 2013-05-14 한국과학기술연구원 리피오돌을 함유하는 컴퓨터 단층촬영용 혈관 조영제
CN102166365B (zh) 2011-04-25 2012-10-24 东南大学 一种多模态碘油纳米乳造影剂的制备方法
DE102012204378A1 (de) 2012-03-20 2013-09-26 Bernd Schwegmann Gmbh & Co. Kg Reinigungsmittel auf Mikroemulsionsbasis
US10786583B2 (en) 2013-09-30 2020-09-29 B.Braun Melsungen Ag Pre-saturation of the liver and subsequent administration of the contrast agent
US10668161B2 (en) 2014-02-24 2020-06-02 The Regents Of The University Of California Therapeutic hyperbranched polyglycerol encapsulated biomolecules
US10157462B2 (en) 2016-06-27 2018-12-18 University Of Central Florida Research Foundation, Inc. System and method for image-based quantification of white and brown adipose tissue at the whole-body, organ and body-region levels

Also Published As

Publication number Publication date
US11654202B2 (en) 2023-05-23
CN111194225A (zh) 2020-05-22
WO2019030024A1 (en) 2019-02-14
CA3072282A1 (en) 2019-02-14
EP3664855A1 (en) 2020-06-17
US20210330820A1 (en) 2021-10-28
AU2018314406A1 (en) 2020-02-20
CN111194225B (zh) 2023-01-13
JP2020529441A (ja) 2020-10-08
EA202090139A1 (ru) 2020-08-06
BR112020002619A2 (pt) 2020-07-28
JP7210542B2 (ja) 2023-01-23

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