CA3054127A1 - Tigit- and light-based chimeric proteins - Google Patents
Tigit- and light-based chimeric proteins Download PDFInfo
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- CA3054127A1 CA3054127A1 CA3054127A CA3054127A CA3054127A1 CA 3054127 A1 CA3054127 A1 CA 3054127A1 CA 3054127 A CA3054127 A CA 3054127A CA 3054127 A CA3054127 A CA 3054127A CA 3054127 A1 CA3054127 A1 CA 3054127A1
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- chimeric protein
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Classifications
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- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
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- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
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- Toxicology (AREA)
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- Biophysics (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Engineering & Computer Science (AREA)
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- Microbiology (AREA)
- Mycology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762464002P | 2017-02-27 | 2017-02-27 | |
| US62/464,002 | 2017-02-27 | ||
| PCT/US2018/020037 WO2018157162A1 (en) | 2017-02-27 | 2018-02-27 | Tigit- and light-based chimeric proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3054127A1 true CA3054127A1 (en) | 2018-08-30 |
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| CA3054127A Pending CA3054127A1 (en) | 2017-02-27 | 2018-02-27 | Tigit- and light-based chimeric proteins |
| CA3054133A Pending CA3054133A1 (en) | 2017-02-27 | 2018-02-27 | Methods of making and using extracellular domain-based chimeric proteins |
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| CA3054133A Pending CA3054133A1 (en) | 2017-02-27 | 2018-02-27 | Methods of making and using extracellular domain-based chimeric proteins |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| MX2019009812A (es) | 2017-02-27 | 2019-10-14 | Shattuck Labs Inc | Proteinas quimericas basadas en tigit y light. |
| JP7511469B2 (ja) | 2017-09-27 | 2024-07-05 | イノザイム ファーマ， インコーポレイテッド | 組換えエクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ（ｎｐｐ１）を使用して心血管機能を改善し、心血管疾患を処置するための方法。 |
| JP7439372B2 (ja) * | 2018-06-21 | 2024-02-28 | シャタック ラボ，インコーポレイテッド | ヘテロ二量体タンパク質及びその使用 |
| CN112912384A (zh) * | 2018-08-29 | 2021-06-04 | 沙塔克实验室有限公司 | 组合疗法 |
| CN112888706A (zh) * | 2018-08-29 | 2021-06-01 | 沙塔克实验室有限公司 | 包含基于tim-3的嵌合蛋白的组合疗法 |
| MX2021002292A (es) * | 2018-08-29 | 2021-05-27 | Shattuck Labs Inc | Terapias de combinacion que comprenden proteinas quimericas basadas en sirp alfa. |
| EP3844280A4 (en) | 2018-08-31 | 2022-09-14 | Yale University | ENPP1 POLYPEPTIDES AND METHODS OF USE |
| MX2021002668A (es) * | 2018-09-05 | 2021-05-12 | Univ Arizona State | Plataforma de virus oncolitico para tratar el cancer hematologico. |
| KR102686295B1 (ko) | 2018-11-21 | 2024-07-19 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 아데노바이러스 및 아데노바이러스의 사용 방법 |
| WO2020176718A1 (en) * | 2019-02-28 | 2020-09-03 | Shattuck Labs, Inc. | Combination therapies |
| CN113710694A (zh) * | 2019-04-29 | 2021-11-26 | 梅奥医学教育及研究基金会 | 用于治疗癌症的多价pd-l1结合化合物 |
| CN112111437B (zh) * | 2020-05-25 | 2023-09-05 | 江南大学 | 2’-岩藻糖基乳糖产量提高的重组枯草芽孢杆菌及其构建方法 |
| KR20230019152A (ko) * | 2020-06-02 | 2023-02-07 | 아르커스 바이오사이언시즈 인코포레이티드 | Tigit에 대한 항체 |
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