CA3050027A1 - Method for fabrication of a two-layered product based on electrospun fibres - Google Patents

Method for fabrication of a two-layered product based on electrospun fibres Download PDF

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Publication number
CA3050027A1
CA3050027A1 CA3050027A CA3050027A CA3050027A1 CA 3050027 A1 CA3050027 A1 CA 3050027A1 CA 3050027 A CA3050027 A CA 3050027A CA 3050027 A CA3050027 A CA 3050027A CA 3050027 A1 CA3050027 A1 CA 3050027A1
Authority
CA
Canada
Prior art keywords
press
temperature
layered product
layered
hydrophilic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3050027A
Other languages
English (en)
French (fr)
Inventor
Jens Hansen
Original Assignee
Afyx Therapeutics AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Afyx Therapeutics AS filed Critical Afyx Therapeutics AS
Publication of CA3050027A1 publication Critical patent/CA3050027A1/en
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B37/00—Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding
    • B32B37/0046—Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by constructional aspects of the apparatus
    • B32B37/0053—Constructional details of laminating machines comprising rollers; Constructional features of the rollers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
    • B29C43/32—Component parts, details or accessories; Auxiliary operations
    • B29C43/44—Compression means for making articles of indefinite length
    • B29C43/46—Rollers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/12—Layered products comprising a layer of synthetic resin next to a fibrous or filamentary layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B37/00—Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding
    • B32B37/06—Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by the heating method
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B37/00—Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding
    • B32B37/10—Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by the pressing technique, e.g. using action of vacuum or fluid pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B5/00—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
    • B32B5/22—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by the presence of two or more layers which are next to each other and are fibrous, filamentary, formed of particles or foamed
    • B32B5/24—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by the presence of two or more layers which are next to each other and are fibrous, filamentary, formed of particles or foamed one layer being a fibrous or filamentary layer
    • B32B5/26—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by the presence of two or more layers which are next to each other and are fibrous, filamentary, formed of particles or foamed one layer being a fibrous or filamentary layer another layer next to it also being fibrous or filamentary
    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
    • D04H1/70—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres
    • D04H1/72—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres the fibres being randomly arranged
    • D04H1/728—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres the fibres being randomly arranged by electro-spinning
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06C—FINISHING, DRESSING, TENTERING OR STRETCHING TEXTILE FABRICS
    • D06C15/00—Calendering, pressing, ironing, glossing or glazing textile fabrics
    • D06C15/02—Calendering, pressing, ironing, glossing or glazing textile fabrics between co-operating press or calender rolls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2556/00—Patches, e.g. medical patches, repair patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Textile Engineering (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Laminated Bodies (AREA)
  • Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
  • Nonwoven Fabrics (AREA)
CA3050027A 2017-01-23 2018-01-22 Method for fabrication of a two-layered product based on electrospun fibres Pending CA3050027A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201770042 2017-01-23
DKPA201770042 2017-01-23
PCT/DK2018/050009 WO2018133909A1 (en) 2017-01-23 2018-01-22 Method for fabrication of a two-layered product based on electrospun fibres

Publications (1)

Publication Number Publication Date
CA3050027A1 true CA3050027A1 (en) 2018-07-26

Family

ID=58536694

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3050027A Pending CA3050027A1 (en) 2017-01-23 2018-01-22 Method for fabrication of a two-layered product based on electrospun fibres

Country Status (14)

Country Link
US (1) US11801671B2 (enExample)
EP (1) EP3570821B1 (enExample)
JP (1) JP7162014B2 (enExample)
KR (1) KR102592782B1 (enExample)
CN (1) CN110248647A (enExample)
AU (1) AU2018209591B2 (enExample)
BR (1) BR112019014236A2 (enExample)
CA (1) CA3050027A1 (enExample)
DK (1) DK3570821T3 (enExample)
ES (1) ES2887977T3 (enExample)
IL (1) IL267916B (enExample)
MX (1) MX382197B (enExample)
RU (1) RU2019125715A (enExample)
WO (1) WO2018133909A1 (enExample)

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CN112107559B (zh) * 2019-06-20 2023-09-08 普济生物科技（台州）有限公司 口腔透粘膜药物剂型
US12115234B2 (en) * 2019-10-07 2024-10-15 The Stellenbosch Nanofiber Company (Pty) Ltd Method of preparing a cosmetic component
CA3157209A1 (en) 2019-10-08 2021-04-15 Afyx Therapeutics A/S Compositions for the delivery of proteins
DE102020129363A1 (de) 2020-11-06 2022-05-12 Selina Jakumeit Schutzvorrichtung als temporäre Versiegelung während sexueller Aktivitäten zur Vermeidung von Harnwegs- und Blasenentzündungen
CN112516368B (zh) * 2020-11-27 2022-05-03 佛山仙湖实验室 一种复合纤维膜及其制备方法和应用
TWI823151B (zh) * 2021-10-01 2023-11-21 南亞塑膠工業股份有限公司 雙層醫用膜及其製法
WO2023094457A1 (en) 2021-11-23 2023-06-01 Afyx Therapeutics A/S Mucosal patches and methods of use thereof
EP4773947A1 (en) 2023-09-06 2026-07-15 Afyx Development A/S Compositions and methods for treating and preventing oral cancer

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Also Published As

Publication number Publication date
EP3570821B1 (en) 2021-07-21
ES2887977T3 (es) 2021-12-29
MX382197B (es) 2025-03-13
US11801671B2 (en) 2023-10-31
AU2018209591B2 (en) 2022-01-20
NZ754820A (en) 2025-02-28
JP2020505461A (ja) 2020-02-20
IL267916B (en) 2022-03-01
MX2019008258A (es) 2020-01-27
KR20190112730A (ko) 2019-10-07
BR112019014236A2 (pt) 2020-03-17
WO2018133909A1 (en) 2018-07-26
RU2019125715A3 (enExample) 2021-05-25
US20190351662A1 (en) 2019-11-21
IL267916A (en) 2019-09-26
CN110248647A (zh) 2019-09-17
RU2019125715A (ru) 2021-02-24
JP7162014B2 (ja) 2022-10-27
DK3570821T3 (da) 2021-10-11
EP3570821A1 (en) 2019-11-27
KR102592782B1 (ko) 2023-10-20
AU2018209591A1 (en) 2019-07-11

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