CA3048966A1 - Hydroxybenzoic acid derivatives, methods and uses thereof - Google Patents

Hydroxybenzoic acid derivatives, methods and uses thereof Download PDF

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Publication number
CA3048966A1
CA3048966A1 CA3048966A CA3048966A CA3048966A1 CA 3048966 A1 CA3048966 A1 CA 3048966A1 CA 3048966 A CA3048966 A CA 3048966A CA 3048966 A CA3048966 A CA 3048966A CA 3048966 A1 CA3048966 A1 CA 3048966A1
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CA
Canada
Prior art keywords
previous
compound according
chain
cancer
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3048966A
Other languages
English (en)
French (fr)
Inventor
Maria Fernanda Martins Borges
Paulo Jorge Gouveia Simoes Da Silva Oliveira
Jose Carlos Santos Teixeira
Fernando Cagide Fagin
Ana Catarina GOMES OLIVEIRA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Porto
Centro de Neurociencias e Biologia Celular
Original Assignee
University of Porto
Centro de Neurociencias e Biologia Celular
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Porto, Centro de Neurociencias e Biologia Celular filed Critical University of Porto
Publication of CA3048966A1 publication Critical patent/CA3048966A1/en
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5442—Aromatic phosphonium compounds (P-C aromatic linkage)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5456—Arylalkanephosphonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA3048966A 2016-12-29 2017-12-29 Hydroxybenzoic acid derivatives, methods and uses thereof Pending CA3048966A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PT109818 2016-12-29
PT10981816 2016-12-29
PCT/IB2017/058508 WO2018122789A1 (en) 2016-12-29 2017-12-29 Hydroxybenzoic acid derivatives, methods and uses thereof

Publications (1)

Publication Number Publication Date
CA3048966A1 true CA3048966A1 (en) 2018-07-05

Family

ID=61074472

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3048966A Pending CA3048966A1 (en) 2016-12-29 2017-12-29 Hydroxybenzoic acid derivatives, methods and uses thereof

Country Status (8)

Country Link
US (1) US11078222B2 (enExample)
EP (1) EP3562830B1 (enExample)
JP (2) JP2020503280A (enExample)
KR (1) KR102750630B1 (enExample)
CN (1) CN110114365B (enExample)
BR (1) BR112019011303B1 (enExample)
CA (1) CA3048966A1 (enExample)
WO (1) WO2018122789A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3925961A4 (en) * 2019-10-30 2022-05-11 Fusion Biotechnology Co., Ltd. Mitochondria-targeting compound and composition comprising same for treating or preventing aging-related diseases
WO2023053059A1 (en) * 2021-09-30 2023-04-06 Universidade Do Porto Antifouling compound, method and uses thereof
WO2023220365A1 (en) * 2022-05-13 2023-11-16 Virginia Tech Intellectual Properties, Inc. Mitochondrial antioxidant treatment for cask-linked neurodevelopmental disorders
US20260097092A1 (en) * 2022-09-21 2026-04-09 Ulsan National Institute Of Science And Technology Pharmaceutical composition containing mitochondria-targeting compound as active ingredient for treating macular degeneration
KR102894216B1 (ko) * 2022-12-15 2025-12-18 울산과학기술원 Trap-1 억제제
CN116210697B (zh) * 2023-03-02 2024-05-14 西北农林科技大学 反式肉桂酸在提高苹果树腐烂病抗性中的应用
KR20250126454A (ko) * 2024-02-16 2025-08-25 울산과학기술원 암 세포의 티오에스테라제 및 활성산소종에 의해 자가 조립 중합되는 단량체 및 이의 용도

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2860266C (en) 2009-04-27 2017-10-31 Iowa State University Research Foundation, Inc. Neuroprotective compounds and their use
GB201320636D0 (en) * 2013-11-22 2014-01-08 Medical Res Council Compounds
MX2018010829A (es) * 2016-03-08 2019-02-07 Univ Michigan Regents Inductores de molécula pequeña de especies de oxígeno reactivo e inhibidores de la actividad mitocondrial.
US10913757B2 (en) * 2016-10-14 2021-02-09 Universidade Do Porto Hydroxycinnamic derivatives, methods and uses thereof

Also Published As

Publication number Publication date
US11078222B2 (en) 2021-08-03
KR20190132622A (ko) 2019-11-28
JP2020503280A (ja) 2020-01-30
BR112019011303B1 (pt) 2023-03-14
EP3562830A1 (en) 2019-11-06
WO2018122789A1 (en) 2018-07-05
JP2023051961A (ja) 2023-04-11
JP7689690B2 (ja) 2025-06-09
CN110114365B (zh) 2022-12-13
KR102750630B1 (ko) 2025-01-06
BR112019011303A2 (pt) 2019-10-08
EP3562830B1 (en) 2023-06-07
US20190330249A1 (en) 2019-10-31
EP3562830C0 (en) 2023-06-07
CN110114365A (zh) 2019-08-09

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