CA3046355C - Glyceryl 3-hydroxybutyrates for traumatic brain injury - Google Patents

Glyceryl 3-hydroxybutyrates for traumatic brain injury Download PDF

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Publication number
CA3046355C
CA3046355C CA3046355A CA3046355A CA3046355C CA 3046355 C CA3046355 C CA 3046355C CA 3046355 A CA3046355 A CA 3046355A CA 3046355 A CA3046355 A CA 3046355A CA 3046355 C CA3046355 C CA 3046355C
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Prior art keywords
hydroxybutyrate
glyceryl
composition
ester
tbi
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CA3046355A
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English (en)
French (fr)
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CA3046355A1 (en
Inventor
Sami HASHIM
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Neuroenergy Ventures Inc
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Neuroenergy Ventures Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3046355A 2017-01-12 2017-11-30 Glyceryl 3-hydroxybutyrates for traumatic brain injury Active CA3046355C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15/404,396 2017-01-12
US15/404,396 US9925164B1 (en) 2017-01-12 2017-01-12 Glyceryl 3-hydroxybutyrates for traumatic brain injury
PCT/US2017/063853 WO2018132189A1 (en) 2017-01-12 2017-11-30 Glyceryl 3-hydroxybutyrates for traumatic brain injury

Publications (2)

Publication Number Publication Date
CA3046355A1 CA3046355A1 (en) 2018-07-19
CA3046355C true CA3046355C (en) 2023-08-01

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA3046355A Active CA3046355C (en) 2017-01-12 2017-11-30 Glyceryl 3-hydroxybutyrates for traumatic brain injury

Country Status (11)

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US (3) US9925164B1 (enExample)
EP (1) EP3568129A4 (enExample)
JP (1) JP7278593B2 (enExample)
KR (1) KR102443942B1 (enExample)
CN (1) CN110114067A (enExample)
BR (1) BR112019014128A2 (enExample)
CA (1) CA3046355C (enExample)
IL (1) IL267934B2 (enExample)
MX (1) MX391851B (enExample)
MY (1) MY207193A (enExample)
WO (1) WO2018132189A1 (enExample)

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US11944598B2 (en) 2017-12-19 2024-04-02 Axcess Global Sciences, Llc Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer
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CN113966323B (zh) * 2019-06-12 2023-11-28 凯托利皮克斯治疗有限责任公司 一种用于生产酮羧酸多元醇基酯的方法
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Also Published As

Publication number Publication date
IL267934B1 (en) 2024-05-01
MY207193A (en) 2025-02-05
KR20190104546A (ko) 2019-09-10
CN110114067A (zh) 2019-08-09
JP7278593B2 (ja) 2023-05-22
JP2020504134A (ja) 2020-02-06
US9925164B1 (en) 2018-03-27
US11638702B2 (en) 2023-05-02
MX2019008269A (es) 2019-09-13
US10736867B2 (en) 2020-08-11
IL267934B2 (en) 2024-09-01
KR102443942B1 (ko) 2022-09-15
IL267934A (en) 2019-09-26
WO2018132189A1 (en) 2018-07-19
EP3568129A4 (en) 2020-12-09
US20180193300A1 (en) 2018-07-12
CA3046355A1 (en) 2018-07-19
US20200297686A1 (en) 2020-09-24
MX391851B (es) 2025-03-21
BR112019014128A2 (pt) 2020-06-16
EP3568129A1 (en) 2019-11-20

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