CN110114067A - 3-羟基丁酸甘油酯用于创伤性脑损伤 - Google Patents

3-羟基丁酸甘油酯用于创伤性脑损伤 Download PDF

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Publication number
CN110114067A
CN110114067A CN201780080457.XA CN201780080457A CN110114067A CN 110114067 A CN110114067 A CN 110114067A CN 201780080457 A CN201780080457 A CN 201780080457A CN 110114067 A CN110114067 A CN 110114067A
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China
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hydroxybutyrate
glyceride
tbi
administration
fatty acyl
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CN201780080457.XA
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English (en)
Chinese (zh)
Inventor
萨米·哈希姆
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Neural Vitality Investment Co
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Neural Vitality Investment Co
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201780080457.XA 2017-01-12 2017-11-30 3-羟基丁酸甘油酯用于创伤性脑损伤 Pending CN110114067A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15/404,396 2017-01-12
US15/404,396 US9925164B1 (en) 2017-01-12 2017-01-12 Glyceryl 3-hydroxybutyrates for traumatic brain injury
PCT/US2017/063853 WO2018132189A1 (en) 2017-01-12 2017-11-30 Glyceryl 3-hydroxybutyrates for traumatic brain injury

Publications (1)

Publication Number Publication Date
CN110114067A true CN110114067A (zh) 2019-08-09

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CN201780080457.XA Pending CN110114067A (zh) 2017-01-12 2017-11-30 3-羟基丁酸甘油酯用于创伤性脑损伤

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Country Link
US (3) US9925164B1 (enExample)
EP (1) EP3568129A4 (enExample)
JP (1) JP7278593B2 (enExample)
KR (1) KR102443942B1 (enExample)
CN (1) CN110114067A (enExample)
BR (1) BR112019014128A2 (enExample)
CA (1) CA3046355C (enExample)
IL (1) IL267934B2 (enExample)
MX (1) MX391851B (enExample)
MY (1) MY207193A (enExample)
WO (1) WO2018132189A1 (enExample)

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US10376528B2 (en) 2017-03-10 2019-08-13 Tecton Group, Llc Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor
US12171735B2 (en) 2017-04-19 2024-12-24 Axcess Global Sciences, Llc Administration of butyrate, beta-hydroxybutyrate, cannabidiol, and related compounds in humans
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US12090129B2 (en) 2017-11-22 2024-09-17 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
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US12329734B2 (en) 2017-12-19 2025-06-17 Axcess Global Sciences, Llc Use of S-beta-hydroxybutyrate compounds for induction and maintenance of flow
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US12186297B2 (en) 2020-08-26 2025-01-07 Axcess Global Sciences, Llc Compositions and methods for increasing lean-to-fat mass ratio
US20240342121A1 (en) * 2021-07-09 2024-10-17 Georgia State University Research Foundation, Inc. The use of beta-hydroxybutyrates for the treatment or prevention of aneurysms and dissections
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WO2023139357A1 (en) * 2022-01-18 2023-07-27 Today Inc. Molecules, nutritional formulations, and methods of providing nutritional support
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Publication number Priority date Publication date Assignee Title
CN116113617A (zh) * 2020-07-13 2023-05-12 Ioi油脂化学品有限责任公司 氧代丁醇酯化的多元羧酸聚甘油酯的制备方法

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KR20190104546A (ko) 2019-09-10
US11638702B2 (en) 2023-05-02
US20180193300A1 (en) 2018-07-12
EP3568129A4 (en) 2020-12-09
US9925164B1 (en) 2018-03-27
IL267934B1 (en) 2024-05-01
IL267934A (en) 2019-09-26
MX391851B (es) 2025-03-21
CA3046355A1 (en) 2018-07-19
CA3046355C (en) 2023-08-01
MY207193A (en) 2025-02-05
JP2020504134A (ja) 2020-02-06
MX2019008269A (es) 2019-09-13
IL267934B2 (en) 2024-09-01
US20200297686A1 (en) 2020-09-24
WO2018132189A1 (en) 2018-07-19
KR102443942B1 (ko) 2022-09-15
JP7278593B2 (ja) 2023-05-22
US10736867B2 (en) 2020-08-11
EP3568129A1 (en) 2019-11-20
BR112019014128A2 (pt) 2020-06-16

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