CA3045666A1 - Treatment of a disease of the gastrointestinal tract with a jak inhibitor and devices - Google Patents
Treatment of a disease of the gastrointestinal tract with a jak inhibitor and devices Download PDFInfo
- Publication number
- CA3045666A1 CA3045666A1 CA3045666A CA3045666A CA3045666A1 CA 3045666 A1 CA3045666 A1 CA 3045666A1 CA 3045666 A CA3045666 A CA 3045666A CA 3045666 A CA3045666 A CA 3045666A CA 3045666 A1 CA3045666 A1 CA 3045666A1
- Authority
- CA
- Canada
- Prior art keywords
- gastrointestinal tract
- disease
- treatment
- devices
- jak inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/00004—Operational features of endoscopes characterised by electronic signal processing
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- A61B1/00002—Operational features of endoscopes
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- A61B1/00009—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
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- A61B1/00064—Constructional details of the endoscope body
- A61B1/00071—Insertion part of the endoscope body
- A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
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- A61B1/00131—Accessories for endoscopes
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/012—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/012—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor
- A61B1/015—Control of fluid supply or evacuation
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- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
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- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
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- A61B1/273—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the upper alimentary canal, e.g. oesophagoscopes, gastroscopes
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- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
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- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- A61M2210/00—Anatomical parts of the body
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- A61M2210/00—Anatomical parts of the body
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- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G01N2333/52—Assays involving cytokines
- G01N2333/555—Interferons [IFN]
- G01N2333/57—IFN-gamma
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Medical Informatics (AREA)
- Radiology & Medical Imaging (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Signal Processing (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662434374P | 2016-12-14 | 2016-12-14 | |
| US62/434,374 | 2016-12-14 | ||
| US201762478919P | 2017-03-30 | 2017-03-30 | |
| US62/478,919 | 2017-03-30 | ||
| US201762545380P | 2017-08-14 | 2017-08-14 | |
| US62/545,380 | 2017-08-14 | ||
| US201762583832P | 2017-11-09 | 2017-11-09 | |
| US62/583,832 | 2017-11-09 | ||
| PCT/US2017/066492 WO2018112245A1 (en) | 2016-12-14 | 2017-12-14 | Treatment of a disease of the gastrointestinal tract with a jak inhibitor and devices |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3045666A1 true CA3045666A1 (en) | 2018-06-21 |
Family
ID=60953958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3045666A Pending CA3045666A1 (en) | 2016-12-14 | 2017-12-14 | Treatment of a disease of the gastrointestinal tract with a jak inhibitor and devices |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11033490B2 (https=) |
| EP (2) | EP3554485B9 (https=) |
| JP (2) | JP2020502126A (https=) |
| KR (1) | KR20190097107A (https=) |
| CN (2) | CN116869457A (https=) |
| AU (2) | AU2017378398B2 (https=) |
| BR (1) | BR112019012062A2 (https=) |
| CA (1) | CA3045666A1 (https=) |
| MX (1) | MX2019006821A (https=) |
| WO (1) | WO2018112245A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3554485B9 (en) * | 2016-12-14 | 2023-09-27 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with a jak inhibitor and devices |
| US11564922B2 (en) | 2017-03-09 | 2023-01-31 | Abbvie Inc. | Methods of treating crohn's disease and ulcerative colitis |
| CN120661512A (zh) * | 2017-03-09 | 2025-09-19 | 艾伯维公司 | 治疗克罗恩病和溃疡性结肠炎的方法 |
| US11541015B2 (en) | 2017-05-17 | 2023-01-03 | Massachusetts Institute Of Technology | Self-righting systems, methods, and related components |
| WO2018213579A1 (en) | 2017-05-17 | 2018-11-22 | Massachusetts Institute Of Technology | Self-actuating articles |
| AU2019269636A1 (en) | 2018-05-17 | 2020-11-19 | Massachusetts Institute Of Technology | Systems for electrical stimulation |
| WO2019246273A1 (en) * | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a jak or other kinase inhibitor |
| CA3123596A1 (en) | 2018-12-19 | 2020-06-25 | Incyte Corporation | Jak1 pathway inhibitors for the treatment of gastrointestinal disease |
| EP4696361A3 (en) | 2019-02-01 | 2026-04-15 | Massachusetts Institute of Technology | Systems and methods for liquid injection |
| CN112393827A (zh) * | 2019-08-12 | 2021-02-23 | 南京理工大学 | 一种可生物降解的压电力传感器的制备方法 |
| WO2021057985A1 (zh) * | 2019-09-27 | 2021-04-01 | 成都中医药大学 | 检测粪钙卫蛋白含量的试剂在制备子宫病变筛查试剂盒中的用途 |
| US11541216B2 (en) | 2019-11-21 | 2023-01-03 | Massachusetts Institute Of Technology | Methods for manufacturing tissue interfacing components |
| US20230107927A1 (en) | 2020-02-28 | 2023-04-06 | First Wave Bio, Inc. | Methods of treating iatrogenic autoimmune colitis |
| TW202207918A (zh) * | 2020-05-14 | 2022-03-01 | 美商施萬生物製藥研發Ip有限責任公司 | 腸道選擇性jak3抑制劑的投與 |
| CN111920812B (zh) * | 2020-07-10 | 2022-09-20 | 深圳市臻质医疗科技有限公司 | 一种钙通道抑制剂氧海罂粟碱在骨关节炎中的应用 |
| CN113081075B (zh) * | 2021-03-09 | 2022-03-04 | 武汉大学 | 一种具有主动式活检与施药功能的磁控胶囊 |
| KR102943558B1 (ko) * | 2021-03-31 | 2026-03-27 | 쿨리아 랩스, 인크. | 휴대용 초분광 시스템 |
| CN118986930B (zh) * | 2024-08-06 | 2025-04-04 | 海南医科大学(海南省医学科学院) | 一种鲁索替尼固体脂质纳米粒及其制备方法 |
| CN119226940B (zh) * | 2024-12-05 | 2025-03-04 | 四川省医学科学院·四川省人民医院 | 一种基于brs加速度的肠道运动智能识别方法及系统 |
| CN120699157B (zh) * | 2025-07-16 | 2025-12-16 | 安康市中心医院 | 一种治疗溃疡性结肠炎的恢复肠屏障功能抗体及其应用 |
Family Cites Families (118)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| IL47062A (en) | 1975-04-10 | 1979-07-25 | Yeda Res & Dev | Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde |
| US4281645A (en) | 1977-06-28 | 1981-08-04 | Duke University, Inc. | Method and apparatus for monitoring metabolism in body organs |
| US4190328A (en) | 1978-12-01 | 1980-02-26 | Levine Robert A | Process for detection of blood-borne parasites |
| JPS5588732A (en) | 1978-12-26 | 1980-07-04 | Olympus Optical Co | Endoscope |
| US4665077A (en) | 1979-03-19 | 1987-05-12 | The Upjohn Company | Method for treating rejection of organ or skin grafts with 6-aryl pyrimidine compounds |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| US5116742A (en) | 1986-12-03 | 1992-05-26 | University Patents, Inc. | RNA ribozyme restriction endoribonucleases and methods |
| US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| US4904582A (en) | 1987-06-11 | 1990-02-27 | Synthetic Genetics | Novel amphiphilic nucleic acid conjugates |
| IL85746A (en) | 1988-03-15 | 1994-05-30 | Yeda Res & Dev | Preparations comprising t-lymphocyte cells treated with 8-methoxypsoralen or cell membranes separated therefrom for preventing or treating autoimmune diseases |
| FI891226A7 (fi) | 1988-04-28 | 1989-10-29 | The Board Of Trustees Of The Leland | Anti-T-solun reseptorideterminantit autoimmuunisairauden hoitoon |
| AU636110B2 (en) | 1988-06-08 | 1993-04-22 | Nichols Institute Diagnostics | Assays utilizing sensitizer-induced production of detectable signal |
| WO1990008187A1 (en) | 1989-01-19 | 1990-07-26 | Dana Farber Cancer Institute | Soluble two domain cd2 protein |
| EP0463101B2 (en) | 1989-03-21 | 2003-03-19 | The Immune Response Corporation | Vaccination and methods against diseases resulting from pathogenic responses by specific t cell populations |
| ATE161850T1 (de) | 1989-07-19 | 1998-01-15 | Connetics Corp | T-zell-rezeptor-peptide als heilmittel für autoimmune und bösartige krankheiten |
| US6251581B1 (en) | 1991-05-22 | 2001-06-26 | Dade Behring Marburg Gmbh | Assay method utilizing induced luminescence |
| US5279607A (en) | 1991-05-30 | 1994-01-18 | The State University Of New York | Telemetry capsule and process |
| US5314805A (en) | 1991-10-28 | 1994-05-24 | Molecular Probes, Inc. | Dual-fluorescence cell viability assay using ethidium homodimer and calcein AM |
| US5318557A (en) | 1992-07-13 | 1994-06-07 | Elan Medical Technologies Limited | Medication administering device |
| AU701578B2 (en) | 1992-08-21 | 1999-02-04 | Vrije Universiteit Brussel | Immunoglobulins devoid of light chains |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| US5763602A (en) | 1996-10-01 | 1998-06-09 | Li; Ying-Syi | Methods of syntheses of phthalocyanine compounds |
| US6171586B1 (en) | 1997-06-13 | 2001-01-09 | Genentech, Inc. | Antibody formulation |
| UA67760C2 (uk) | 1997-12-11 | 2004-07-15 | Міннесота Майнінг Енд Мануфакчурінг Компані | Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки |
| US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| AU2679899A (en) | 1998-02-18 | 1999-09-06 | Dade Behring Inc. | Chemiluminescent compositions for use in detection of multiple analytes |
| US6331530B1 (en) | 1999-07-13 | 2001-12-18 | The Trustees Of Columbia University In The City Of New York | Hydrophilic carrier for photosensitizers that cleaves when they catalyze the formation of singlet oxygen |
| US6703248B1 (en) | 1999-12-15 | 2004-03-09 | Dade Behring Marburg Gmbh | Particles for diagnostic and therapeutic use |
| GB9930000D0 (en) | 1999-12-21 | 2000-02-09 | Phaeton Research Ltd | An ingestible device |
| US20030117491A1 (en) | 2001-07-26 | 2003-06-26 | Dov Avni | Apparatus and method for controlling illumination in an in-vivo imaging device |
| US6949347B2 (en) | 2002-03-05 | 2005-09-27 | Aclara Biosciences, Inc. | Multiplex analysis using membrane-bound sensitizers |
| US7797033B2 (en) | 2002-04-08 | 2010-09-14 | Smart Pill Corporation | Method of using, and determining location of, an ingestible capsule |
| DE60334378D1 (de) * | 2002-07-05 | 2010-11-11 | Temrel Ltd | Zusammensetzung zur kontrollierten wirkstoffabgabe |
| US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
| AU2004208580A1 (en) | 2003-01-29 | 2004-08-12 | E-Pill Pharma Ltd. | Active drug delivery in the gastrointestinal tract |
| US20060104968A1 (en) | 2003-03-05 | 2006-05-18 | Halozyme, Inc. | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases |
| US7871607B2 (en) | 2003-03-05 | 2011-01-18 | Halozyme, Inc. | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases |
| EP1643906A2 (en) | 2003-06-12 | 2006-04-12 | University of Utah Research Foundation | Apparatus, systems and methods for diagnosing carpal tunnel syndrome |
| US7402398B2 (en) | 2003-07-17 | 2008-07-22 | Monogram Biosciences, Inc. | Measuring receptor homodimerization |
| US20050065441A1 (en) | 2003-08-29 | 2005-03-24 | Arkady Glukhovsky | System, apparatus and method for measurement of motion parameters of an in-vivo device |
| JP4445732B2 (ja) | 2003-08-29 | 2010-04-07 | オリンパス株式会社 | 被検体内導入装置および無線型被検体内情報取得システム |
| JP2005074031A (ja) | 2003-09-01 | 2005-03-24 | Pentax Corp | カプセル内視鏡 |
| AU2004275804A1 (en) | 2003-09-23 | 2005-04-07 | Light Sciences Oncology, Inc. | Conjugates for photodynamic therapy |
| US8206285B2 (en) | 2003-12-31 | 2012-06-26 | Given Imaging Ltd. | Apparatus, system and method to indicate in-vivo device location |
| DE602005021475D1 (de) * | 2004-03-26 | 2010-07-08 | Lek Pharmaceuticals | Magenresistente pharmazeutische dosierform mit n-(2-(2-phthalimidoethoxy)-acetyl)-l-alanyl-d-glutaminsäure (lk-423) |
| WO2005112895A2 (en) * | 2004-05-20 | 2005-12-01 | Spectrum Dynamics Llc | Ingestible device platform for the colon |
| AU2005245224A1 (en) | 2004-05-21 | 2005-12-01 | Given Imaging Ltd. | Device, system and method for in-vivo sampling |
| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| JP2008532568A (ja) * | 2005-01-18 | 2008-08-21 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 電子制御されるカプセル |
| NZ563580A (en) | 2005-06-07 | 2010-09-30 | Esbatech An Alcon Biomedical R | Stable and soluble antibodies inhibiting TNFaplha |
| US20070027362A1 (en) | 2005-07-27 | 2007-02-01 | Olympus Medical Systems Corp. | Infrared observation system |
| KR20130108481A (ko) | 2005-08-19 | 2013-10-02 | 아보트 러보러터리즈 | 이원 가변 도메인 면역글로불린 및 이의 용도 |
| US7612181B2 (en) | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| US8338416B2 (en) * | 2006-03-16 | 2012-12-25 | Pharmacylics, Inc. | Indole derivatives as inhibitors of histone deacetylase |
| EP2063785A4 (en) | 2006-09-06 | 2011-08-31 | Innurvation Inc | SYSTEM AND METHOD FOR EXCHANGE OF ACOUSTIC INFORMATION INVOLVING A LOW-POWERFUL CAPABLE OF INTEGRATION |
| JP5528810B2 (ja) * | 2006-10-31 | 2014-06-25 | コーニンクレッカ フィリップス エヌ ヴェ | 消化管において薬品を放出するための飲み込み可能なマルチノズルの投薬デバイス |
| CN101622352A (zh) * | 2006-12-29 | 2010-01-06 | 美国奥斯普瑞医药公司 | 选择和产生修饰的毒素、含有修饰的毒素的缀合物的方法及其应用 |
| EP2125076B1 (en) | 2007-02-26 | 2012-06-20 | Duocure, Inc. | Spray administration of compositions including active agents such as peptides to the gastrointestinal tract |
| JP4932588B2 (ja) | 2007-05-08 | 2012-05-16 | オリンパス株式会社 | 画像処理装置および画像処理プログラム |
| EP2725035A1 (en) | 2007-10-02 | 2014-04-30 | Avaxia Biologics, Inc. | Antibody therapy for use in the digestive tract |
| CN101945613B (zh) | 2008-02-18 | 2014-08-13 | 皇家飞利浦电子股份有限公司 | 为患者用药 |
| KR100931946B1 (ko) | 2009-06-10 | 2009-12-15 | 주식회사 인트로메딕 | 캡슐 내시경에 의해 촬영된 이미지 데이터를 저장하고 있는 서버로부터 관심있는 데이터를 우선하여 단말기에 수신하여 확인할 수 있도록 하는 서버-클라이언트 시스템의 이미지 데이터 전송 프로세싱 방법 |
| WO2011004395A1 (en) | 2009-07-06 | 2011-01-13 | Intas Biopharmaceuticals Limited | Microemulsion formulation for biologicals |
| JP6030956B2 (ja) | 2009-08-05 | 2016-11-24 | テル ハショマー メディカル リサーチ インフラストラクチャー アンド サーヴィシーズ リミテッド | 胃腸管の異常の診断に使える情報を提供する方法と機器 |
| US9026192B2 (en) | 2009-11-24 | 2015-05-05 | Given Imaging Ltd | Device and method for in vivo imaging |
| US20130129675A1 (en) * | 2009-12-04 | 2013-05-23 | Board Of Regents, The University Of Texas System | Interferon therapies in combination with blockade of stat3 activation |
| EP2571573A4 (en) | 2010-03-17 | 2013-12-04 | Photopill Medical Ltd | PHOTOTHERAPY BY CAPSULE |
| EP2588105A1 (en) | 2010-07-01 | 2013-05-08 | Cellzome Limited | Triazolopyridines as tyk2 inhibitors |
| MX2013005445A (es) | 2010-11-19 | 2013-07-29 | Hoffmann La Roche | Pirazolopiridinas y el uso de pirazolopiridinas como inhibidores de tirosina cinasa 2 (tyk2). |
| US9527925B2 (en) * | 2011-04-01 | 2016-12-27 | Boehringer Ingelheim International Gmbh | Bispecific binding molecules binding to VEGF and ANG2 |
| JP5238100B2 (ja) | 2011-04-01 | 2013-07-17 | オリンパスメディカルシステムズ株式会社 | 受信装置及びカプセル型内視鏡システム |
| US20140228715A1 (en) * | 2011-05-13 | 2014-08-14 | The General Hospital Corporation | Method and Apparatus for Delivering a Substance |
| US8907081B2 (en) | 2011-05-27 | 2014-12-09 | Sharp Laboratories Of America, Inc. | Long wavelength absorbing porphyrin photosensitizers for dye-sensitized solar cells |
| EP2554544A1 (en) * | 2011-08-01 | 2013-02-06 | Almirall, S.A. | Pyridin-2(1h)-one derivatives as jak inhibitors |
| US9198900B2 (en) * | 2011-11-10 | 2015-12-01 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Treatment of peritoneal injury using JAK inhibitors |
| CA2857597A1 (en) | 2011-11-30 | 2013-06-06 | AbbVie Deutschland GmbH & Co. KG | Methods and compositions for determining responsiveness to treatment with a tnf-alpha inhibitor |
| CN104271028B (zh) | 2011-12-15 | 2017-11-17 | 基文影像公司 | 确定患者的胃肠道随时间的出血曲线的类型的系统 |
| US9795330B2 (en) | 2011-12-15 | 2017-10-24 | Given Imaging Ltd. | Device, system and method for in-vivo detection of bleeding in the gastrointestinal tract |
| WO2013113326A1 (en) | 2012-01-31 | 2013-08-08 | Curevac Gmbh | Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen |
| FR2986432B1 (fr) | 2012-02-06 | 2014-03-14 | Univ Lille Ii Droit & Sante | Proteines 28kda gst provenant de schistosomes pour leur utilisation dans le traitement des maladies inflammatoires auto-immunes engendrant une reponse de type th1 et/ou th17 |
| WO2013120184A1 (en) | 2012-02-17 | 2013-08-22 | Micropharma Limited | Ingestible medical device |
| DK2634185T3 (en) | 2012-03-02 | 2016-03-21 | Sareum Ltd | Tyk2 kinase inhibitors |
| EP2855451B1 (en) | 2012-05-24 | 2017-10-04 | Cellzome Limited | Heterocyclyl pyrimidine analogues as tyk2 inhibitors |
| AU2013274030B2 (en) * | 2012-06-15 | 2016-07-07 | Sun Pharmaceutical Industries, Inc. | Deuterated derivatives of ruxolitinib |
| CN113384546A (zh) * | 2012-11-15 | 2021-09-14 | 因赛特公司 | 鲁索利替尼的缓释剂型 |
| TWI527811B (zh) * | 2013-05-09 | 2016-04-01 | 吉李德科學股份有限公司 | 作爲溴結構域抑制劑的苯並咪唑衍生物 |
| SG11201509371XA (en) | 2013-05-24 | 2015-12-30 | Nestec Sa | Pathway specific markers for diagnosing irritable bowel syndrome |
| JP2016528174A (ja) * | 2013-05-31 | 2016-09-15 | セルリアン・ファーマ・インコーポレイテッド | 治療的送達用のシクロデキストリンベースのポリマー |
| US9324145B1 (en) | 2013-08-08 | 2016-04-26 | Given Imaging Ltd. | System and method for detection of transitions in an image stream of the gastrointestinal tract |
| EP3750590B8 (en) | 2013-09-26 | 2025-08-13 | BT Bidco, Inc. | Delivery capsule with threshold release |
| EP3060234A1 (en) | 2013-10-24 | 2016-08-31 | AbbVie Inc. | Jak1 selective inhibitor and uses thereof |
| WO2015099749A1 (en) | 2013-12-27 | 2015-07-02 | Capso Vision Inc. | Capsule camera device with multi-spectral light sources |
| BR112016015140A2 (pt) | 2013-12-30 | 2018-01-23 | Epimab Biotherapeutics Inc. | imunoglobulina com fabs in-tandem e usos das mesmas |
| WO2015112575A1 (en) | 2014-01-22 | 2015-07-30 | The Board Of Regents Of The University Of Nebraska | Gastrointestinal sensor implantation system |
| WO2015183886A1 (en) | 2014-05-30 | 2015-12-03 | Schaeffler Technologies Gmbh & Co. Kg | Torque converter including spherical clutch |
| RU2697851C2 (ru) * | 2014-08-13 | 2019-08-21 | Седарс-Синаи Медикал Сентер | Антиметаногенные композиции и их применение |
| EP4706525A3 (en) * | 2014-09-25 | 2026-04-22 | BT Bidco, Inc. | Electromechanical pill device with localization capabilities |
| US9714288B2 (en) | 2014-09-30 | 2017-07-25 | The Regents Of The University Of California | Antisense compounds and uses thereof |
| CN104473611B (zh) | 2015-01-19 | 2018-01-30 | 吉林大学 | 具有超声波定位功能的胶囊内窥镜系统 |
| CN105877685B (zh) | 2015-01-26 | 2019-03-15 | 香港中文大学 | 内窥镜胶囊和内窥镜系统 |
| EP3262049B1 (en) | 2015-02-27 | 2022-07-20 | Nimbus Lakshmi, Inc. | Tyk2 inhibitors and uses thereof |
| KR20170122776A (ko) * | 2015-03-06 | 2017-11-06 | 신세틱 바이오로직스, 인코퍼레이티드 | 마이크로바이옴 보호를 위한 안전하고 유효한 베타-락타마제 투약 |
| EP3302265B1 (en) * | 2015-05-31 | 2023-08-02 | Check-Cap Ltd. | Drug delivery capsule |
| JP2017012395A (ja) | 2015-06-30 | 2017-01-19 | 富士フイルム株式会社 | 内視鏡システム及び内視鏡システムの作動方法 |
| EP3500177A1 (en) | 2016-08-18 | 2019-06-26 | Mitchell Lawrence Jones | Systems for obtaining samples using ingestible devices |
| KR20230042759A (ko) | 2016-09-09 | 2023-03-29 | 비오라 쎄라퓨틱스, 인크. | 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스 |
| CA3036334A1 (en) | 2016-09-09 | 2018-03-15 | Mitchell Lawrence Jones | Systems and methods for extracting a sample from an ingestible device |
| US10610104B2 (en) | 2016-12-07 | 2020-04-07 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| EP3554485B9 (en) * | 2016-12-14 | 2023-09-27 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with a jak inhibitor and devices |
| WO2018111466A1 (en) | 2016-12-14 | 2018-06-21 | Mitchell Lawrence Jones | Ingestible device recovery system |
| CA3046975A1 (en) | 2016-12-15 | 2018-06-21 | Progenity, Inc. | Ingestible device and associated methods |
| EP3900613B1 (en) | 2017-03-31 | 2023-12-27 | Biora Therapeutics, Inc. | Localization methods for an ingestible device |
| WO2019246273A1 (en) * | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a jak or other kinase inhibitor |
| KR20240132261A (ko) | 2021-11-17 | 2024-09-03 | 에이치2 클리퍼, 인크. | 로봇 공학을 이용한 비행선 제작에 대한 개선된 시스템, 방법 및 장치 |
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