CA3044355A1 - Methods of enhancing immune response with everolimus, dactolisib or both - Google Patents
Methods of enhancing immune response with everolimus, dactolisib or both Download PDFInfo
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- CA3044355A1 CA3044355A1 CA3044355A CA3044355A CA3044355A1 CA 3044355 A1 CA3044355 A1 CA 3044355A1 CA 3044355 A CA3044355 A CA 3044355A CA 3044355 A CA3044355 A CA 3044355A CA 3044355 A1 CA3044355 A1 CA 3044355A1
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
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- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662425766P | 2016-11-23 | 2016-11-23 | |
| US62/425,766 | 2016-11-23 | ||
| US201762476160P | 2017-03-24 | 2017-03-24 | |
| US62/476,160 | 2017-03-24 | ||
| US201762576511P | 2017-10-24 | 2017-10-24 | |
| US62/576,511 | 2017-10-24 | ||
| PCT/IB2017/001579 WO2018096402A1 (en) | 2016-11-23 | 2017-11-22 | Methods of enhancing immune response with everolimus, dactolisib or both |
Publications (1)
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| CA3044355A1 true CA3044355A1 (en) | 2018-05-31 |
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| CA3044355A Abandoned CA3044355A1 (en) | 2016-11-23 | 2017-11-22 | Methods of enhancing immune response with everolimus, dactolisib or both |
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| US (3) | US10441584B2 (https=) |
| EP (1) | EP3544608A1 (https=) |
| JP (1) | JP2020500930A (https=) |
| KR (1) | KR20190089005A (https=) |
| CN (1) | CN110114070A (https=) |
| AU (1) | AU2017363970A1 (https=) |
| BR (1) | BR112019010470A2 (https=) |
| CA (1) | CA3044355A1 (https=) |
| IL (1) | IL266750A (https=) |
| MX (1) | MX2019006090A (https=) |
| TW (1) | TW201825090A (https=) |
| WO (1) | WO2018096402A1 (https=) |
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| US11083725B2 (en) | 2014-10-24 | 2021-08-10 | St. Jude Children's Research Hospital | Coordinated metabolic reprogramming in response to productive viral infections |
| CN110114070A (zh) | 2016-11-23 | 2019-08-09 | 诺华公司 | 使用依维莫司(everolimus)、达托里昔布(dactolisib)或二者增强免疫反应的方法 |
| US10596165B2 (en) | 2018-02-12 | 2020-03-24 | resTORbio, Inc. | Combination therapies |
| WO2020223154A1 (en) * | 2019-05-01 | 2020-11-05 | resTORbio, Inc. | Methods of enhancing immune response |
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| HK1245095A1 (zh) * | 2015-05-20 | 2018-08-24 | Novartis Ag | 依维莫司(everolimus)与达托里昔布(dactolisib)的医药组合 |
| CN110114070A (zh) | 2016-11-23 | 2019-08-09 | 诺华公司 | 使用依维莫司(everolimus)、达托里昔布(dactolisib)或二者增强免疫反应的方法 |
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2017
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- 2017-11-22 CA CA3044355A patent/CA3044355A1/en not_active Abandoned
- 2017-11-22 MX MX2019006090A patent/MX2019006090A/es unknown
- 2017-11-22 JP JP2019547795A patent/JP2020500930A/ja active Pending
- 2017-11-22 AU AU2017363970A patent/AU2017363970A1/en not_active Abandoned
- 2017-11-22 KR KR1020197017560A patent/KR20190089005A/ko not_active Withdrawn
- 2017-11-22 US US15/821,229 patent/US10441584B2/en active Active
- 2017-11-22 BR BR112019010470A patent/BR112019010470A2/pt not_active Application Discontinuation
- 2017-11-22 TW TW106140519A patent/TW201825090A/zh unknown
- 2017-11-22 EP EP17829013.6A patent/EP3544608A1/en not_active Withdrawn
- 2017-11-22 WO PCT/IB2017/001579 patent/WO2018096402A1/en not_active Ceased
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2019
- 2019-05-20 IL IL266750A patent/IL266750A/en unknown
- 2019-10-03 US US16/592,248 patent/US11045463B2/en active Active
- 2019-10-03 US US16/592,293 patent/US10993940B2/en active Active
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| AU2017363970A1 (en) | 2019-06-20 |
| IL266750A (en) | 2019-07-31 |
| US10441584B2 (en) | 2019-10-15 |
| CN110114070A (zh) | 2019-08-09 |
| KR20190089005A (ko) | 2019-07-29 |
| US20180161319A1 (en) | 2018-06-14 |
| US20200061051A1 (en) | 2020-02-27 |
| WO2018096402A1 (en) | 2018-05-31 |
| US11045463B2 (en) | 2021-06-29 |
| EP3544608A1 (en) | 2019-10-02 |
| BR112019010470A2 (pt) | 2019-09-10 |
| US20200054624A1 (en) | 2020-02-20 |
| JP2020500930A (ja) | 2020-01-16 |
| TW201825090A (zh) | 2018-07-16 |
| US10993940B2 (en) | 2021-05-04 |
| MX2019006090A (es) | 2019-08-21 |
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