CA3038422A1 - Uses of recombinant yeast-derived serum albumin - Google Patents

Uses of recombinant yeast-derived serum albumin Download PDF

Info

Publication number
CA3038422A1
CA3038422A1 CA3038422A CA3038422A CA3038422A1 CA 3038422 A1 CA3038422 A1 CA 3038422A1 CA 3038422 A CA3038422 A CA 3038422A CA 3038422 A CA3038422 A CA 3038422A CA 3038422 A1 CA3038422 A1 CA 3038422A1
Authority
CA
Canada
Prior art keywords
serum albumin
storage medium
stem cells
cryopreservation
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3038422A
Other languages
English (en)
French (fr)
Inventor
Eva Balslev Jorgensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Albumedix Ltd
Original Assignee
Albumedix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Albumedix Ltd filed Critical Albumedix Ltd
Publication of CA3038422A1 publication Critical patent/CA3038422A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/128—Chemically defined matrices for immobilising, holding or storing living parts, e.g. alginate gels; Chemically altering living parts, e.g. by cross-linking
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0635—B lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Dispersion Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA3038422A 2016-10-04 2017-10-04 Uses of recombinant yeast-derived serum albumin Pending CA3038422A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16192276.0 2016-10-04
EP16192276 2016-10-04
PCT/EP2017/075257 WO2018065491A1 (en) 2016-10-04 2017-10-04 Uses of recombinant yeast-derived serum albumin

Publications (1)

Publication Number Publication Date
CA3038422A1 true CA3038422A1 (en) 2018-04-12

Family

ID=57047137

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3038422A Pending CA3038422A1 (en) 2016-10-04 2017-10-04 Uses of recombinant yeast-derived serum albumin

Country Status (8)

Country Link
US (1) US20190216079A1 (enExample)
EP (3) EP3429345B1 (enExample)
JP (2) JP6928084B2 (enExample)
KR (2) KR102573478B1 (enExample)
CA (1) CA3038422A1 (enExample)
DK (1) DK3429345T3 (enExample)
ES (1) ES2761854T3 (enExample)
WO (1) WO2018065491A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3111273C (en) 2018-09-06 2024-03-26 Bavarian Nordic A/S Storage improved poxvirus compositions
EP3982724A1 (en) 2019-06-11 2022-04-20 Axogen Corporation Wet preservation of tissue
WO2021111143A1 (en) 2019-12-04 2021-06-10 Albumedix Limited Methods and compositions produced thereby
JP7712284B2 (ja) 2020-03-12 2025-07-23 バヴァリアン・ノルディック・アクティーゼルスカブ ポックスウイルスの安定性を改善する組成物
CN113549653B (zh) * 2020-04-23 2024-03-22 上海赛比曼生物科技有限公司 用于慢病毒载体长期存贮的组合试剂
JP7280623B2 (ja) * 2020-12-28 2023-05-24 株式会社アビー 細胞凍結保存液、及び細胞凍結方法
JP7318983B2 (ja) * 2021-12-21 2023-08-01 株式会社アビー 細胞凍結保存液、及び細胞凍結方法
WO2024018452A1 (en) 2022-07-18 2024-01-25 Yeda Research And Development Co. Ltd. Albumin protein variants, production thereof and uses of same
CN117783501B (zh) * 2024-02-26 2024-05-10 四川大学华西第二医院 辛酸钠在注意缺陷与多动障碍中的应用及产品

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
FR2746109B1 (fr) * 1996-03-12 1998-04-17 Rhone Poulenc Rorer Sa Milieu pour la conservation de materiel biologique
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
JP4798832B2 (ja) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 ヒト血清アルブミン多量体の除去方法
CN1275981C (zh) 2000-10-24 2006-09-20 财团法人化学及血清疗法研究所 人血清白蛋白多聚体的单体化方法
JP4798833B2 (ja) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 加熱処理工程を含むヒト血清アルブミンの製造方法
JP2004238392A (ja) * 2003-01-14 2004-08-26 Nipro Corp 安定化された蛋白質性製剤
GB0310347D0 (en) 2003-05-07 2003-06-11 Delta Biotechnology Ltd Assay
AU2005205314B2 (en) 2004-01-20 2010-12-09 Km Biologics Co., Ltd. Process for producing human serum albumin by heating in presence of divalent cation
WO2009057537A1 (ja) * 2007-11-02 2009-05-07 Jcr Pharmaceuticals Co., Ltd. ヒト間葉系幹細胞含有医薬組成物
KR101722961B1 (ko) 2009-02-11 2017-04-04 알부메딕스 에이/에스 알부민 변이체 및 접합체
CN102549012B (zh) * 2009-05-07 2015-07-01 诺维信生物制药丹麦公司 纯化白蛋白的方法
MX2012004793A (es) 2009-10-30 2012-07-20 Novozymes Biopharma Dk As Variantes de albumina.
WO2011075686A2 (en) * 2009-12-18 2011-06-23 Ventria Bioscience Methods & compositions comprising heat shock proteins
SG182618A1 (en) * 2010-01-25 2012-08-30 Ventria Bioscience Methods & compositions for improving protein production
JP5969458B2 (ja) 2010-04-09 2016-08-17 アルブミディクス アクティーゼルスカブ アルブミン誘導体及び変異体
CN103649111B (zh) 2011-07-05 2018-03-13 阿尔布梅迪克斯医疗公司 白蛋白制剂和用途
EP2885969B1 (en) * 2013-12-19 2018-06-27 FertiPro N.V. Cryopreservation tools and methods

Also Published As

Publication number Publication date
EP3429345A1 (en) 2019-01-23
WO2018065491A1 (en) 2018-04-12
US20190216079A1 (en) 2019-07-18
ES2761854T3 (es) 2020-05-21
KR102573478B1 (ko) 2023-09-04
KR102662031B1 (ko) 2024-05-03
KR20230128591A (ko) 2023-09-05
EP3603391A1 (en) 2020-02-05
JP7249387B2 (ja) 2023-03-30
EP3429345B1 (en) 2019-09-11
DK3429345T3 (da) 2019-11-25
JP2021176336A (ja) 2021-11-11
EP3791719A1 (en) 2021-03-17
JP6928084B2 (ja) 2021-09-01
KR20190052075A (ko) 2019-05-15
JP2019533442A (ja) 2019-11-21

Similar Documents

Publication Publication Date Title
EP3429345B1 (en) Uses of recombinant yeast-derived serum albumin
US11485953B2 (en) Compositions and methods for maintaining cell viability
US10104881B2 (en) Composition comprising plant-derived recombinant human serum albumin, lipids, and plant protein hydrolysates as active ingredients for cryopreservation of stem cells or primary cells
JP6879949B2 (ja) 治療目的のための細胞の凍結保存方法
KR20160026863A (ko) 트레할로스 및 덱스트란 함유 포유동물 세포 이식용 용액
KR101407355B1 (ko) 식물 유래의 재조합 인간 혈청 알부민, 지질 및 식물 단백질 가수분해물을 유효성분으로 포함하는 줄기세포 또는 일차배양세포의 동결보존용 조성물
Mirabel et al. Stability enhancement of clinical grade multipotent mesenchymal stromal cell-based products
Mahiddine et al. Conditioned medium from canine amniotic membrane-derived mesenchymal stem cells improved dog sperm post-thaw quality-related parameters
JPWO2014208100A1 (ja) 間葉系細胞を利用した巨核球、血小板及び／又はトロンボポエチンの製造方法
Kappler et al. The cytoprotective capacity of processed human cardiac extracellular matrix
US20150313948A1 (en) Treating oral lesions using placental extracellular matrix
HK40048841A (en) Uses of recombinant yeast-derived serum albumin
KR102665782B1 (ko) 동결 및 동결건조된 미토콘드리아 및 이의 용도
US20210315199A1 (en) Cryopreservation medium for umbilical cord mscs derived from wharton's jelly
KR102536863B1 (ko) 양막유래 줄기세포-조정배지를 포함하는 동물의 정액 동결보호용 조성물 및 이의 제조방법
CA2444468A1 (en) A composition for the culture of cells, in particular animal cells or tissues, comprising polyethylene glycol
BE1031137B1 (nl) Cryopreservatie formulering omvattende collageenhydrolysaat
RU2773747C2 (ru) Устойчивая жидкая фармацевтическая композиция
WO2017195745A1 (ja) 培地、アルブミン非含有培地用添加剤および多能性幹細胞の培養方法
Ekrem Development of an optimal xeno-free cGMP growth medium for the culture of corneal stroma-derived mesenchymal stem cells
US20180245046A1 (en) METHOD FOR PRODUCING MESENCHYMAL CELLS WITH PROMOTED c-MPL RECEPTOR EXPRESSION ON CELL SURFACE

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20190326

EEER Examination request

Effective date: 20190326

EEER Examination request

Effective date: 20190326

EEER Examination request

Effective date: 20190326

EEER Examination request

Effective date: 20190326

EEER Examination request

Effective date: 20190326

EEER Examination request

Effective date: 20190326