CA3011704A1 - Methods and systems for rapid detection of microorganisms using infectious agents - Google Patents

Methods and systems for rapid detection of microorganisms using infectious agents Download PDF

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Publication number
CA3011704A1
CA3011704A1 CA3011704A CA3011704A CA3011704A1 CA 3011704 A1 CA3011704 A1 CA 3011704A1 CA 3011704 A CA3011704 A CA 3011704A CA 3011704 A CA3011704 A CA 3011704A CA 3011704 A1 CA3011704 A1 CA 3011704A1
Authority
CA
Canada
Prior art keywords
bacteriophage
indicator
sample
hours
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3011704A
Other languages
English (en)
French (fr)
Inventor
Jose S. GIL
Stephen Erickson
Ben Barrett HOPKINS
Minh Mindy Bao NGUYEN
Dwight Lyman ANDERSON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratory Corp of America Holdings
Original Assignee
Laboratory Corp of America Holdings
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/263,619 external-priority patent/US20170131275A1/en
Application filed by Laboratory Corp of America Holdings filed Critical Laboratory Corp of America Holdings
Publication of CA3011704A1 publication Critical patent/CA3011704A1/en
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/73Expression systems using phage (lambda) regulatory sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/10Enterobacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA3011704A 2016-01-18 2017-01-18 Methods and systems for rapid detection of microorganisms using infectious agents Pending CA3011704A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662280043P 2016-01-18 2016-01-18
US62/280,043 2016-01-18
US201662280465P 2016-01-19 2016-01-19
US62/280,465 2016-01-19
US15/263,619 2016-09-13
US15/263,619 US20170131275A1 (en) 2012-02-21 2016-09-13 Methods and systems for detection of microorganisms
PCT/US2017/013955 WO2017127434A1 (en) 2016-01-18 2017-01-18 Methods and systems for rapid detection of microorganisms using infectious agents

Publications (1)

Publication Number Publication Date
CA3011704A1 true CA3011704A1 (en) 2017-07-27

Family

ID=59362121

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3011704A Pending CA3011704A1 (en) 2016-01-18 2017-01-18 Methods and systems for rapid detection of microorganisms using infectious agents

Country Status (8)

Country Link
EP (1) EP3405590A1 (ja)
JP (2) JP2019509020A (ja)
CN (2) CN108884498A (ja)
AU (1) AU2017209041B2 (ja)
BR (1) BR112018014166A2 (ja)
CA (1) CA3011704A1 (ja)
MX (1) MX2018008778A (ja)
WO (1) WO2017127434A1 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10519483B2 (en) 2012-02-21 2019-12-31 Laboratory Corporation Of America Holdings Methods and systems for rapid detection of microorganisms using infectious agents
AU2019208101A1 (en) * 2018-01-12 2020-06-18 Laboratory Corporation Of America Holdings Methods and systems for the rapid detection of Salmonella using infectious agents
CN112313337A (zh) * 2018-04-24 2021-02-02 美国控股实验室公司 选择和监测治疗功效的指示物噬菌体及其使用方法
BR112021013769A2 (pt) * 2019-01-29 2021-09-21 Laboratory Corporation Of America Holdings Métodos e sistemas para a detecção rápida de listeria usando agentes infecciosos.
CA3140294A1 (en) * 2019-06-21 2020-12-24 Jose S. GIL Methods for producing mutant bacteriophages for the detection of listeria
EP4022045A1 (en) 2019-08-26 2022-07-06 Laboratory Corporation of America Holdings Devices and methods for detecting microorganisms using recombinant reproduction-deficient indicator bacteriophage
AU2020347269A1 (en) * 2019-09-11 2022-03-31 Laboratory Corporation Of America Holdings Methods and systems for the rapid detection of microorganisms using recombinant infectious agents to express an indicator subunit
WO2022094393A1 (en) * 2020-10-30 2022-05-05 Albert Einstein College Of Medicine Reporter mycobacteriophage, assays and methods comprising the reporter mycobacteriophage
AU2021387969A1 (en) * 2020-11-25 2023-06-22 Laboratory Corporation Of America Holdings Methods and systems for the detection of microorganisms using infectious agents

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19517940A1 (de) * 1995-05-18 1996-11-21 Merck Patent Gmbh Nachweis von Listerien mittels rekombinanter Bakteriophagen
WO2003035889A2 (en) * 2001-07-13 2003-05-01 Investigen, Inc. Compositions and methods for bacteria detection
JP4235718B2 (ja) * 2003-03-07 2009-03-11 株式会社荏原製作所 大腸菌の検出方法及び大腸菌検出用ファージ
CN1298840C (zh) * 2003-09-24 2007-02-07 冯书章 肠出血性大肠杆菌o157基因缺失疫苗
EP1888088A4 (en) * 2005-05-26 2012-07-04 Chr Hansen As BACTERIAL REGULATION IN ANIMAL CONTAINMENT SYSTEMS
WO2008124119A1 (en) * 2007-04-05 2008-10-16 Sequella, Inc. Improved methods and compositions for determining the pathogenic status of infectious agents
CA2684311A1 (en) * 2007-04-18 2008-10-30 Cornell University Microorganism detection method and apparatus
US8114622B2 (en) * 2008-08-29 2012-02-14 Purdue Research Foundation Methods for generation of reporter phages and immobilization of active bacteriophages on a polymer surface
CN104245961B (zh) * 2012-02-21 2017-05-10 美国控股实验室公司 用于微生物检测的方法和系统
US10519483B2 (en) * 2012-02-21 2019-12-31 Laboratory Corporation Of America Holdings Methods and systems for rapid detection of microorganisms using infectious agents
KR101299179B1 (ko) * 2012-04-18 2013-08-22 씨제이제일제당 (주) 신규 박테리오파지 및 이를 포함하는 항균 조성물
JP6300222B2 (ja) * 2013-09-25 2018-03-28 国立大学法人東京工業大学 遺伝子組換えウイルスによる微生物の迅速検出法
JP6767268B2 (ja) * 2014-02-18 2020-10-21 ラボラトリー コーポレイション オブ アメリカ ホールディングス 組み換えバクテリオファージを使用する、微生物の迅速検出のための方法及びシステム
CA2947441A1 (en) * 2014-05-09 2015-11-12 Sample6 Technologies, Inc. Codon-optimized recombinant phage and methods of using same

Also Published As

Publication number Publication date
CN108884498A (zh) 2018-11-23
JP2022024167A (ja) 2022-02-08
AU2017209041A1 (en) 2018-07-26
WO2017127434A1 (en) 2017-07-27
EP3405590A1 (en) 2018-11-28
BR112018014166A2 (pt) 2018-12-26
MX2018008778A (es) 2018-09-12
JP2019509020A (ja) 2019-04-04
AU2017209041B2 (en) 2023-03-30
CN115960844A (zh) 2023-04-14

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