CA2998796A1 - Pyrazolopyrimidine derivatives as btk inhibitors for the treatment of cancer - Google Patents
Pyrazolopyrimidine derivatives as btk inhibitors for the treatment of cancer Download PDFInfo
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- CA2998796A1 CA2998796A1 CA2998796A CA2998796A CA2998796A1 CA 2998796 A1 CA2998796 A1 CA 2998796A1 CA 2998796 A CA2998796 A CA 2998796A CA 2998796 A CA2998796 A CA 2998796A CA 2998796 A1 CA2998796 A1 CA 2998796A1
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- phenyl
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| PCT/GB2016/052897 WO2017046604A1 (en) | 2015-09-16 | 2016-09-16 | Pyrazolopyrimidine derivatives as btk inhibitors for the treatment of cancer |
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| JP7337502B2 (ja) | 2015-09-16 | 2023-09-04 | ロクソ オンコロジー， インコーポレイテッド | がんの治療のためのｂｔｋ阻害剤としてのピラゾロピリミジン誘導体 |
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| WO2019222509A1 (en) * | 2018-05-16 | 2019-11-21 | The University Of North Carolina At Chapel Hill | Pyrazolopyrimidines as mertk inhibitors and their application in cancer treatment |
| CN110964016B (zh) * | 2018-09-29 | 2021-05-28 | 南京药捷安康生物科技有限公司 | 氨基降茨烷衍生物及其制备方法与应用 |
| CN111454268B (zh) * | 2019-01-18 | 2023-09-08 | 明慧医药（上海）有限公司 | 作为布鲁顿酪氨酸激酶抑制剂的环状分子 |
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| WO2022169798A2 (en) * | 2021-02-03 | 2022-08-11 | Accutar Biotechnology, Inc. | Substituted pyrrolopyrimidine and pyrazolopyrimidine as bruton's tyrosine kinase (btk) degraders |
| WO2023110970A1 (en) | 2021-12-14 | 2023-06-22 | Netherlands Translational Research Center Holding B.V | Macrocyclic btk inhibitors |
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