CA2996383A1 - Immunomodulatory compositions and methods of use thereof - Google Patents
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- CA2996383A1 CA2996383A1 CA2996383A CA2996383A CA2996383A1 CA 2996383 A1 CA2996383 A1 CA 2996383A1 CA 2996383 A CA2996383 A CA 2996383A CA 2996383 A CA2996383 A CA 2996383A CA 2996383 A1 CA2996383 A1 CA 2996383A1
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- UCRLQOPRDMGYOA-DFTDUNEMSA-L zinc;(4r)-4-[[(2s)-2-[[(4r)-2-[(1s,2s)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2s,3s)-1-[[(3s,6r,9s,12r,15s,18r,21s)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2s)-butan-2-yl]-6-(carbox Chemical compound [Zn+2].C1SC([C@@H](N)[C@@H](C)CC)=N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC([O-])=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]1C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2NC=NC=2)C(=O)N[C@H](CC([O-])=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC1 UCRLQOPRDMGYOA-DFTDUNEMSA-L 0.000 description 1
- XDWXRAYGALQIFG-UHFFFAOYSA-L zinc;propanoate Chemical compound [Zn+2].CCC([O-])=O.CCC([O-])=O XDWXRAYGALQIFG-UHFFFAOYSA-L 0.000 description 1
- 229940107931 zovirax Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Transplantation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562209693P | 2015-08-25 | 2015-08-25 | |
| US62/209,693 | 2015-08-25 | ||
| PCT/IB2016/055016 WO2017033123A1 (en) | 2015-08-25 | 2016-08-22 | Immunomodulatory compositions and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2996383A1 true CA2996383A1 (en) | 2017-03-02 |
Family
ID=58100011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2996383A Pending CA2996383A1 (en) | 2015-08-25 | 2016-08-22 | Immunomodulatory compositions and methods of use thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US11065283B2 (enExample) |
| EP (2) | EP4480544A3 (enExample) |
| JP (1) | JP7223989B2 (enExample) |
| CN (1) | CN107921113A (enExample) |
| AU (2) | AU2016311387B2 (enExample) |
| CA (1) | CA2996383A1 (enExample) |
| HK (1) | HK1248531A1 (enExample) |
| WO (1) | WO2017033123A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017214383A1 (en) * | 2016-06-10 | 2017-12-14 | The Johns Hopkins University | USE OF C1q/TNF-RELATED PROTEIN-1 (CTRP1) TO TREAT FATTY LIVER DISEASE |
| CN108888762A (zh) * | 2018-08-15 | 2018-11-27 | 福建傲农生物科技集团股份有限公司 | 一种含益生菌代谢产物的组合物 |
| CN109966320B (zh) * | 2019-04-26 | 2022-08-05 | 青岛东海药业有限公司 | 凝结芽孢杆菌在制备诱导抗肿瘤免疫及免疫检查点抑制剂增敏制剂中的应用 |
| JP2022534783A (ja) * | 2019-06-03 | 2022-08-03 | イミュノルクス インターナショナル コーポレーション | 疾患を処置するための天然痘ワクチン及び幹細胞 |
| KR102149102B1 (ko) * | 2019-07-05 | 2020-08-27 | 에스케이바이오랜드 주식회사 | 피부보습 및 피부재생 기능이 있는 더모바이오틱스 블록 조성물의 제조방법 |
| EP3838269A1 (en) * | 2019-12-16 | 2021-06-23 | European Molecular Biology Laboratory | Compounds and pharmaceutical compositions for prevention and/or treatment of dysbiosis and antibacterial antidotes for microbiome-protection |
| CN113440609A (zh) * | 2020-03-27 | 2021-09-28 | 北京市农林科学院 | 一种双链rna复合物autp及其在疫苗制备中的应用 |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| CN113198004B (zh) * | 2021-05-19 | 2022-08-19 | 天津市宝恒生物科技有限公司 | 一种修复肠粘膜的凝结芽孢杆菌制剂 |
| CN113975278B (zh) * | 2021-10-29 | 2023-04-07 | 中国科学院昆明动物研究所 | 溴隐亭在制备治疗非洲猪瘟的产品中的应用 |
| US20250230230A1 (en) * | 2022-03-24 | 2025-07-17 | The Brigham And Women's Hospital, Inc. | Treatment of perivascular fibrosis and other hypertensive diseases and conditions |
| CN121218993A (zh) * | 2023-03-15 | 2025-12-26 | 拓比利亚欧斯特有限公司(Acn 652 771 670) | 用于治疗、改善或预防病毒感染的制造产品和治疗组合物及其制备和使用方法 |
| US12268717B1 (en) | 2024-03-01 | 2025-04-08 | Malireddy S. Reddy | Enhanced microbial therapeutic agents |
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| IL47062A (en) | 1975-04-10 | 1979-07-25 | Yeda Res & Dev | Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde |
| US4665077A (en) | 1979-03-19 | 1987-05-12 | The Upjohn Company | Method for treating rejection of organ or skin grafts with 6-aryl pyrimidine compounds |
| GB8815795D0 (en) | 1988-07-02 | 1988-08-10 | Bkl Extrusions Ltd | Glazing bead |
| HU212924B (en) | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| US5736371A (en) | 1991-06-04 | 1998-04-07 | A Et S Biovecteurs | Biodegradable particulate vector for transporting molecules having biological activity |
| ES2141108T3 (es) | 1991-07-02 | 2000-03-16 | Inhale Inc | Metodo y dispositivo para proporcionar medicamentos en aerosol. |
| US5711968A (en) | 1994-07-25 | 1998-01-27 | Alkermes Controlled Therapeutics, Inc. | Composition and method for the controlled release of metal cation-stabilized interferon |
| EP0671948B1 (en) | 1992-06-25 | 1997-08-13 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Vaccine composition containing adjuvants |
| US5785049A (en) | 1994-09-21 | 1998-07-28 | Inhale Therapeutic Systems | Method and apparatus for dispersion of dry powder medicaments |
| DK0689454T4 (da) | 1993-03-23 | 2005-05-30 | Smithkline Beecham Biolog | Vaccinepræparater indeholdende 3-O-deacyleret monophosphoryl-lipid A |
| US5497763A (en) | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
| JP3220331B2 (ja) | 1993-07-20 | 2001-10-22 | エチコン・インコーポレーテツド | 非経口投与用の吸収性液体コポリマー類 |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| JP3468773B2 (ja) | 1994-07-15 | 2003-11-17 | ザ ユニバーシティ オブ アイオワ リサーチ ファウンデーション | 免疫調節オリゴヌクレオチド |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| GB9513261D0 (en) | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
| ES2241042T3 (es) | 1996-10-11 | 2005-10-16 | The Regents Of The University Of California | Conjugados de polinucleotido inmunoestimulador/ molecula inmunomoduladora. |
| EP0842657A1 (en) | 1996-11-19 | 1998-05-20 | OctoPlus B.V. | Microspheres for controlled release and processes to prepare these microspheres |
| EP1039935A4 (en) | 1997-02-28 | 2005-04-27 | Univ Iowa Res Found | USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS |
| WO1998040100A1 (en) | 1997-03-10 | 1998-09-17 | Ottawa Civic Loeb Research Institute | USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE AS AN ADJUVANT |
| US6339068B1 (en) | 1997-05-20 | 2002-01-15 | University Of Iowa Research Foundation | Vectors and methods for immunization or therapeutic protocols |
| ATE432348T1 (de) | 1997-06-06 | 2009-06-15 | Univ California | Inhibitoren von immunstimulatorischen dna sequenz aktivität |
| GB9712347D0 (en) | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
| GEP20022707B (en) | 1997-07-18 | 2002-06-25 | Infimed Inc Us | Biodegrading Macromers for the Controlled Release of Biologically Active Substances |
| EP1009382B1 (en) | 1997-09-05 | 2003-06-18 | GlaxoSmithKline Biologicals S.A. | Oil in water emulsions containing saponins |
| EP1051157B1 (en) | 1998-01-30 | 2002-01-02 | Scios Inc. | Controlled release delivery of peptide or protein |
| US6303114B1 (en) | 1998-03-05 | 2001-10-16 | The Medical College Of Ohio | IL-12 enhancement of immune responses to T-independent antigens |
| EP1069910A1 (en) | 1998-04-09 | 2001-01-24 | GlaxoSmithKline Biologicals S.A. | Adjuvant compositions |
| GB9817052D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
| PL201482B1 (pl) | 1998-10-16 | 2009-04-30 | Smithkline Beecham Biolog | Sposoby wytwarzania kompozycji szczepionki oraz kompozycja szczepionki |
| US6143314A (en) | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
| WO2000050073A2 (en) * | 1999-02-22 | 2000-08-31 | University Of British Columbia | Caulobacter lps immunoadjuvant |
| DK1163000T3 (da) | 1999-03-19 | 2008-04-28 | Glaxosmithkline Biolog Sa | Vacciner imod antigener fra bakterier |
| DK1187629T3 (da) | 1999-04-19 | 2005-01-17 | Glaxosmithkline Biolog Sa | Adjuvanssammensætning omfattende saponin og et immunostimulerende oligonucleotid |
| BR0014285A (pt) | 1999-09-24 | 2002-05-21 | Smithkline Beecham Biolog | Adjuvantes compreendendo um éster ou éter de alquila de polioxietileno e pelo menos um tensoativo não-iÈnico |
| PL355163A1 (en) | 1999-09-24 | 2004-04-05 | Smithkline Beecham Biologicals S.A. | Use of combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines |
| US6458398B1 (en) | 1999-10-18 | 2002-10-01 | Eco Pure Food Safety Systems, Inc. | Cold water disinfection of foods |
| EP1255823A4 (en) | 2000-01-28 | 2007-10-31 | Azopax Therapeutics Llc | PROTEIN POLYMERS WITH SLOW RELEASE |
| US6296842B1 (en) | 2000-08-10 | 2001-10-02 | Alkermes Controlled Therapeutics, Inc. | Process for the preparation of polymer-based sustained release compositions |
| EP1377275B1 (en) | 2001-03-27 | 2006-10-25 | Biomira, Inc. | Vaccine for modulating between t1 and t2 immune responses |
| US8501198B2 (en) | 2004-06-07 | 2013-08-06 | Qu Biologics Inc. | Tissue targeted antigenic activation of the immune response to treat cancers |
| CN106102771B (zh) | 2014-01-07 | 2021-06-29 | 巴比塔·阿格拉沃尔 | 免疫调节组合物及其使用方法 |
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2016
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- 2016-08-22 EP EP24200626.0A patent/EP4480544A3/en active Pending
- 2016-08-22 WO PCT/IB2016/055016 patent/WO2017033123A1/en not_active Ceased
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- 2016-08-22 HK HK18107924.6A patent/HK1248531A1/zh unknown
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2023
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| EP3341017B1 (en) | 2024-10-16 |
| US11065283B2 (en) | 2021-07-20 |
| US20180243347A1 (en) | 2018-08-30 |
| AU2016311387B2 (en) | 2023-02-23 |
| EP4480544A2 (en) | 2024-12-25 |
| WO2017033123A1 (en) | 2017-03-02 |
| EP4480544A3 (en) | 2025-03-26 |
| US11701393B2 (en) | 2023-07-18 |
| JP7223989B2 (ja) | 2023-02-17 |
| CN107921113A (zh) | 2018-04-17 |
| EP3341017A4 (en) | 2019-07-17 |
| JP2018531886A (ja) | 2018-11-01 |
| EP3341017A1 (en) | 2018-07-04 |
| HK1248531A1 (zh) | 2018-10-19 |
| AU2016311387A1 (en) | 2018-03-29 |
| US20230084577A1 (en) | 2023-03-16 |
| AU2023203076A1 (en) | 2023-06-08 |
| US20210369792A1 (en) | 2021-12-02 |
| US11419904B2 (en) | 2022-08-23 |
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