CA2990507A1 - Novel cell epitopes and combination of cell epitopes for use in the immuno-therapy of myeloma and other cancers - Google Patents
Novel cell epitopes and combination of cell epitopes for use in the immuno-therapy of myeloma and other cancers Download PDFInfo
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| US62/184,500 | 2015-06-25 | ||
| GB1511191.7 | 2015-06-25 | ||
| PCT/EP2016/064317 WO2016207164A2 (en) | 2015-06-25 | 2016-06-21 | Novel cell epitopes and combination of cell epitopes for use in the immuno-therapy of myeloma and other cancers |
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| CA2990507A1 true CA2990507A1 (en) | 2016-12-29 |
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| US9340800B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | Extended DNA-sensing GRNAS |
| WO2015077717A1 (en) | 2013-11-25 | 2015-05-28 | The Broad Institute Inc. | Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status |
| US11725237B2 (en) | 2013-12-05 | 2023-08-15 | The Broad Institute Inc. | Polymorphic gene typing and somatic change detection using sequencing data |
| EP3082853A2 (en) | 2013-12-20 | 2016-10-26 | The Broad Institute, Inc. | Combination therapy with neoantigen vaccine |
| WO2016022363A2 (en) | 2014-07-30 | 2016-02-11 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
| US10993997B2 (en) | 2014-12-19 | 2021-05-04 | The Broad Institute, Inc. | Methods for profiling the t cell repertoire |
| EP3234193B1 (en) | 2014-12-19 | 2020-07-15 | Massachusetts Institute of Technology | Molecular biomarkers for cancer immunotherapy |
| EP3362929B1 (en) * | 2015-10-12 | 2020-08-12 | Nantomics, LLC | Viral neoepitopes and uses thereof |
| IL258821B (en) | 2015-10-23 | 2022-07-01 | Harvard College | Nucleobase editors and their uses |
| CA3008641A1 (en) | 2015-12-16 | 2017-06-22 | Gritstone Oncology, Inc. | Neoantigen identification, manufacture, and use |
| CN108700566A (zh) | 2016-02-19 | 2018-10-23 | 河谷控股Ip有限责任公司 | 免疫原性调节的方法 |
| GB201609193D0 (en) | 2016-05-25 | 2016-07-06 | Immatics Biotechnologies Gmbh | Novel peptides, combination of peptides as targets for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers |
| JP7075125B2 (ja) | 2016-05-25 | 2022-05-25 | イマティクス バイオテクノロジーズ ゲーエムベーハー | 標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ |
| US20190167722A1 (en) * | 2016-08-02 | 2019-06-06 | Nant Holdings Ip, Llc | Transfection of dendritic cells and methods therefor |
| WO2018039438A1 (en) | 2016-08-24 | 2018-03-01 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| KR102379955B1 (ko) | 2016-12-08 | 2022-03-29 | 이매틱스 바이오테크놀로지스 게엠베하 | 짝짓기가 향상된 t 세포 수용체 |
| DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
| CN110662556A (zh) * | 2017-03-09 | 2020-01-07 | 哈佛大学的校长及成员们 | 癌症疫苗 |
| JP2020510439A (ja) | 2017-03-10 | 2020-04-09 | プレジデント アンド フェローズ オブ ハーバード カレッジ | シトシンからグアニンへの塩基編集因子 |
| CN110944660A (zh) | 2017-04-10 | 2020-03-31 | 伊玛提克斯生物技术有限公司 | 用于白血病和其他癌症免疫治疗的肽和肽组合物 |
| EA201992416A1 (ru) | 2017-04-10 | 2020-02-25 | Имматикс Байотекнолоджиз Гмбх | Пептиды и комбинации пептидов для применения в иммунотерапии лейкозов и других видов рака |
| WO2018224166A1 (en) * | 2017-06-09 | 2018-12-13 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy |
| LT3652215T (lt) | 2017-07-14 | 2021-05-25 | Immatics Biotechnologies Gmbh | Pagerinta dvejopo savitumo polipeptido molekulė |
| DE102017115966A1 (de) | 2017-07-14 | 2019-01-17 | Immatics Biotechnologies Gmbh | Polypeptidmolekül mit verbesserter zweifacher Spezifität |
| JP2020534795A (ja) | 2017-07-28 | 2020-12-03 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ファージによって支援される連続的進化（ｐａｃｅ）を用いて塩基編集因子を進化させるための方法および組成物 |
| WO2019075112A1 (en) | 2017-10-10 | 2019-04-18 | Gritstone Oncology, Inc. | IDENTIFICATION OF NEO-ANTIGENS USING HOT POINTS |
| EP3714275A4 (en) | 2017-11-22 | 2021-10-27 | Gritstone bio, Inc. | REDUCTION OF JUNCTION EPITOPIC PRESENTATION FOR NEOANTIGENS |
| DE102017127984B4 (de) | 2017-11-27 | 2019-12-05 | Immatics US, Inc. | Verfahren für die Vermehrung und Aktivierung von γδ-T-Zellen |
| CN107937515B (zh) * | 2017-12-06 | 2018-11-09 | 北京泱深生物信息技术有限公司 | 一种阿尔茨海默的诊疗基因靶点及其应用 |
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| GB201511191D0 (en) | 2015-08-12 |
| EP3313860A2 (en) | 2018-05-02 |
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| US10196422B2 (en) | 2019-02-05 |
| EA201792484A1 (ru) | 2018-05-31 |
| MA46508A1 (fr) | 2021-09-30 |
| WO2016207164A3 (en) | 2017-02-02 |
| JP2018520653A (ja) | 2018-08-02 |
| BR112017027639A2 (pt) | 2018-09-11 |
| AU2016284857A1 (en) | 2017-12-07 |
| US20170022251A1 (en) | 2017-01-26 |
| MA46506A1 (fr) | 2021-03-31 |
| MA46507A1 (fr) | 2021-03-31 |
| MX2017016207A (es) | 2018-07-06 |
| MA46504A1 (fr) | 2021-03-31 |
| US20190077832A1 (en) | 2019-03-14 |
| WO2016207164A2 (en) | 2016-12-29 |
| CN107889489A (zh) | 2018-04-06 |
| CR20180051A (es) | 2018-05-25 |
| PE20180174A1 (es) | 2018-01-22 |
| KR20180012865A (ko) | 2018-02-06 |
| US10377797B2 (en) | 2019-08-13 |
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