CA2990507A1 - Novel cell epitopes and combination of cell epitopes for use in the immuno-therapy of myeloma and other cancers - Google Patents
Novel cell epitopes and combination of cell epitopes for use in the immuno-therapy of myeloma and other cancers Download PDFInfo
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| GB1511191.7 | 2015-06-25 | ||
| PCT/EP2016/064317 WO2016207164A2 (en) | 2015-06-25 | 2016-06-21 | Novel cell epitopes and combination of cell epitopes for use in the immuno-therapy of myeloma and other cancers |
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| CA2990507A1 true CA2990507A1 (en) | 2016-12-29 |
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| US11725237B2 (en) | 2013-12-05 | 2023-08-15 | The Broad Institute Inc. | Polymorphic gene typing and somatic change detection using sequencing data |
| EP3082853A2 (en) | 2013-12-20 | 2016-10-26 | The Broad Institute, Inc. | Combination therapy with neoantigen vaccine |
| US10077453B2 (en) | 2014-07-30 | 2018-09-18 | President And Fellows Of Harvard College | CAS9 proteins including ligand-dependent inteins |
| US10975442B2 (en) | 2014-12-19 | 2021-04-13 | Massachusetts Institute Of Technology | Molecular biomarkers for cancer immunotherapy |
| EP3234130B1 (en) | 2014-12-19 | 2020-11-25 | The Broad Institute, Inc. | Methods for profiling the t-cell- receptor repertoire |
| MX387275B (es) | 2015-10-12 | 2025-03-18 | Nantomics Llc | Neoepítopos virales y sus usos |
| US12043852B2 (en) | 2015-10-23 | 2024-07-23 | President And Fellows Of Harvard College | Evolved Cas9 proteins for gene editing |
| EP4299136A3 (en) | 2015-12-16 | 2024-02-14 | Gritstone bio, Inc. | Neoantigen identification, manufacture, and use |
| US11585805B2 (en) | 2016-02-19 | 2023-02-21 | Nantcell, Inc. | Methods of immunogenic modulation |
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| JP7075125B2 (ja) | 2016-05-25 | 2022-05-25 | イマティクス バイオテクノロジーズ ゲーエムベーハー | 標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ |
| US20190167722A1 (en) * | 2016-08-02 | 2019-06-06 | Nant Holdings Ip, Llc | Transfection of dendritic cells and methods therefor |
| WO2018039438A1 (en) | 2016-08-24 | 2018-03-01 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
| EP4317432A3 (en) | 2016-12-08 | 2024-04-17 | Immatics Biotechnologies GmbH | T cell receptors with improved pairing |
| JP2020510038A (ja) * | 2017-03-09 | 2020-04-02 | プレジデント アンド フェローズ オブ ハーバード カレッジ | がんワクチン |
| CN110914310A (zh) | 2017-03-10 | 2020-03-24 | 哈佛大学的校长及成员们 | 胞嘧啶至鸟嘌呤碱基编辑器 |
| EA201992416A1 (ru) | 2017-04-10 | 2020-02-25 | Имматикс Байотекнолоджиз Гмбх | Пептиды и комбинации пептидов для применения в иммунотерапии лейкозов и других видов рака |
| CR20190509A (es) | 2017-04-10 | 2020-01-08 | Immatics Biotechnologies Gmbh | Péptidos y combinaciones de péptidos para el uso en la inmunoterapia contra la leucemia y otros tipos de cáncer |
| WO2018224166A1 (en) * | 2017-06-09 | 2018-12-13 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy |
| HUE054568T2 (hu) | 2017-07-14 | 2021-09-28 | Immatics Biotechnologies Gmbh | Továbbfejlesztett kettõs specificitású polipeptid molekula |
| DE102017115966A1 (de) | 2017-07-14 | 2019-01-17 | Immatics Biotechnologies Gmbh | Polypeptidmolekül mit verbesserter zweifacher Spezifität |
| JP2020534795A (ja) | 2017-07-28 | 2020-12-03 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ファージによって支援される連続的進化（ｐａｃｅ）を用いて塩基編集因子を進化させるための方法および組成物 |
| EP3694532B1 (en) | 2017-10-10 | 2025-02-26 | Gritstone bio, Inc. | Neoantigen identification using hotspots |
| IL274799B2 (en) | 2017-11-22 | 2025-05-01 | Gritstone Bio Inc | Reducing junction epitope presentation for neoantigens |
| DE102017127984B4 (de) | 2017-11-27 | 2019-12-05 | Immatics US, Inc. | Verfahren für die Vermehrung und Aktivierung von γδ-T-Zellen |
| CN107937515B (zh) * | 2017-12-06 | 2018-11-09 | 北京泱深生物信息技术有限公司 | 一种阿尔茨海默的诊疗基因靶点及其应用 |
| US12406749B2 (en) | 2017-12-15 | 2025-09-02 | The Broad Institute, Inc. | Systems and methods for predicting repair outcomes in genetic engineering |
| SG11202007543TA (en) | 2018-02-09 | 2020-09-29 | Immatics Us Inc | Methods for manufacturing t cells |
| DE102018108612A1 (de) | 2018-03-21 | 2019-09-26 | Immatics US, Inc. | Verfahren zur erhöhung der persistenz von adoptiv infundierten t-zellen |
| TW202016131A (zh) * | 2018-05-16 | 2020-05-01 | 德商英麥提克生物技術股份有限公司 | 用於抗癌免疫治療的肽 |
| US12157760B2 (en) | 2018-05-23 | 2024-12-03 | The Broad Institute, Inc. | Base editors and uses thereof |
| TW202019955A (zh) | 2018-07-31 | 2020-06-01 | 德商英麥提克生物技術股份有限公司 | B*07 限制肽和肽組合的抗癌免疫治療和相關方法 |
| CN113195715A (zh) * | 2018-08-29 | 2021-07-30 | 阿迈瑞斯公司 | 基于选择的测定法的细胞和方法 |
| MX2021002333A (es) * | 2018-08-30 | 2021-04-28 | Univ Montreal | Metodo basado en proteogenomica para identificar antigenos especificos de tumores. |
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| MA46504A1 (fr) | 2021-03-31 |
| MA46506A1 (fr) | 2021-03-31 |
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| GB201511191D0 (en) | 2015-08-12 |
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| EP3313860A2 (en) | 2018-05-02 |
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| MA46507A1 (fr) | 2021-03-31 |
| KR20180012865A (ko) | 2018-02-06 |
| WO2016207164A2 (en) | 2016-12-29 |
| US10196422B2 (en) | 2019-02-05 |
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| WO2016207164A3 (en) | 2017-02-02 |
| US10377797B2 (en) | 2019-08-13 |
| BR112017027639A2 (pt) | 2018-09-11 |
| AU2016284857A1 (en) | 2017-12-07 |
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