CA2985615A1 - Procedes lies a crispr/cas et compositions pour traiter une infection par le vih et le sida - Google Patents
Procedes lies a crispr/cas et compositions pour traiter une infection par le vih et le sida Download PDFInfo
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- CA2985615A1 CA2985615A1 CA2985615A CA2985615A CA2985615A1 CA 2985615 A1 CA2985615 A1 CA 2985615A1 CA 2985615 A CA2985615 A CA 2985615A CA 2985615 A CA2985615 A CA 2985615A CA 2985615 A1 CA2985615 A1 CA 2985615A1
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Abstract
L'invention concerne des systèmes liés à CRISPR CAS, des compositions et des procédés pour l'édition de gènes CXCR4 et/ou CCR5 dans des cellules humaines, ainsi que des cellules et des compositions comprenant des cellules éditées selon l'invention.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562159778P | 2015-05-11 | 2015-05-11 | |
| US62/159,778 | 2015-05-11 | ||
| PCT/US2016/031922 WO2016183236A1 (fr) | 2015-05-11 | 2016-05-11 | Procédés liés à crispr/cas et compositions pour traiter une infection par le vih et le sida |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2985615A1 true CA2985615A1 (fr) | 2016-11-17 |
Family
ID=56098348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2985615A Abandoned CA2985615A1 (fr) | 2015-05-11 | 2016-05-11 | Procedes lies a crispr/cas et compositions pour traiter une infection par le vih et le sida |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20180119123A1 (fr) |
| EP (1) | EP3294888A1 (fr) |
| AU (1) | AU2016262521A1 (fr) |
| CA (1) | CA2985615A1 (fr) |
| WO (1) | WO2016183236A1 (fr) |
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| EP3613852A3 (fr) | 2011-07-22 | 2020-04-22 | President and Fellows of Harvard College | Évaluation et amélioration de la spécificité de clivage des nucléases |
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| US10967298B2 (en) | 2012-03-15 | 2021-04-06 | Flodesign Sonics, Inc. | Driver and control for variable impedence load |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US9950282B2 (en) | 2012-03-15 | 2018-04-24 | Flodesign Sonics, Inc. | Electronic configuration and control for acoustic standing wave generation |
| US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9737604B2 (en) | 2013-09-06 | 2017-08-22 | President And Fellows Of Harvard College | Use of cationic lipids to deliver CAS9 |
| US9340800B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | Extended DNA-sensing GRNAS |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| US20150166984A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting alpha-antitrypsin point mutations |
| CA2935960C (fr) | 2014-01-08 | 2023-01-10 | Bart Lipkens | Dispositif d'acoustophorese avec double chambre acoustophoretique |
| WO2016022363A2 (fr) | 2014-07-30 | 2016-02-11 | President And Fellows Of Harvard College | Protéines cas9 comprenant des intéines dépendant de ligands |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
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| IL258821B (en) | 2015-10-23 | 2022-07-01 | Harvard College | Nucleobase editors and their uses |
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| WO2018027036A1 (fr) * | 2016-08-03 | 2018-02-08 | Dipersio John F | Édition génétique des cellules car-t pour le traitement de malignités des lymphocytes t avec des récepteurs d'antigènes chimériques |
| SG11201900907YA (en) | 2016-08-03 | 2019-02-27 | Harvard College | Adenosine nucleobase editors and uses thereof |
| US11661590B2 (en) | 2016-08-09 | 2023-05-30 | President And Fellows Of Harvard College | Programmable CAS9-recombinase fusion proteins and uses thereof |
| US11542509B2 (en) | 2016-08-24 | 2023-01-03 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| IT201600102542A1 (it) * | 2016-10-12 | 2018-04-12 | Univ Degli Studi Di Trento | Plasmide e sistema lentivirale contenente un circuito autolimitante della Cas9 che ne incrementa la sicurezza. |
| GB2573062A (en) | 2016-10-14 | 2019-10-23 | Harvard College | AAV delivery of nucleobase editors |
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| KR20230019843A (ko) | 2020-05-08 | 2023-02-09 | 더 브로드 인스티튜트, 인코퍼레이티드 | 표적 이중 가닥 뉴클레오티드 서열의 두 가닥의 동시 편집을 위한 방법 및 조성물 |
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| US7074596B2 (en) | 2002-03-25 | 2006-07-11 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Synthesis and use of anti-reverse mRNA cap analogues |
| EP2049665A2 (fr) | 2006-07-28 | 2009-04-22 | Applera Corporation | ANALOGUES DE COIFFES DE NUCLÉOTIDE D'ARNm |
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| PL215513B1 (pl) | 2008-06-06 | 2013-12-31 | Univ Warszawski | Nowe boranofosforanowe analogi dinukleotydów, ich zastosowanie, czasteczka RNA, sposób otrzymywania RNA oraz sposób otrzymywania peptydów lub bialka |
| US8969545B2 (en) | 2011-10-18 | 2015-03-03 | Life Technologies Corporation | Alkynyl-derivatized cap analogs, preparation and uses thereof |
| WO2014165825A2 (fr) * | 2013-04-04 | 2014-10-09 | President And Fellows Of Harvard College | Utilisations thérapeutiques de l'édition de génome au moyen de systèmes crispr/cas |
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| US11278572B2 (en) * | 2014-07-18 | 2022-03-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Reducing CXCR4 expression and/or function to enhance engraftment of hematopoietic stem cells |
| CN104480144B (zh) * | 2014-12-12 | 2017-04-12 | 武汉大学 | 用于艾滋病基因治疗的CRISPR/Cas9重组慢病毒载体及其慢病毒 |
| CN105400779A (zh) * | 2015-10-15 | 2016-03-16 | 芜湖医诺生物技术有限公司 | 嗜热链球菌CRISPR-Cas9系统识别的人CCR5基因的靶序列和sgRNA及其应用 |
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| CN105316324A (zh) * | 2015-10-20 | 2016-02-10 | 芜湖医诺生物技术有限公司 | 嗜热链球菌CRISPR-Cas9系统识别的人CXCR4基因的靶序列和sgRNA及其应用 |
| CN105331608A (zh) * | 2015-10-20 | 2016-02-17 | 芜湖医诺生物技术有限公司 | 脑膜炎双球菌CRISPR-Cas9系统识别的人CXCR4基因的靶序列和sgRNA及其应用 |
| CN105331609A (zh) * | 2015-10-20 | 2016-02-17 | 芜湖医诺生物技术有限公司 | 脑膜炎双球菌CRISPR-Cas9系统识别的人CCR5基因的靶序列和sgRNA及其应用 |
| CN105316337A (zh) * | 2015-10-20 | 2016-02-10 | 芜湖医诺生物技术有限公司 | 嗜热链球菌CRISPR-Cas9系统识别的人CXCR4基因的靶序列和sgRNA及其应用 |
| CN105567688A (zh) * | 2016-01-27 | 2016-05-11 | 武汉大学 | 一种可用于艾滋病基因治疗的CRISPR/SaCas9系统 |
-
2016
- 2016-05-11 CA CA2985615A patent/CA2985615A1/fr not_active Abandoned
- 2016-05-11 AU AU2016262521A patent/AU2016262521A1/en not_active Abandoned
- 2016-05-11 WO PCT/US2016/031922 patent/WO2016183236A1/fr unknown
- 2016-05-11 EP EP16727014.9A patent/EP3294888A1/fr active Pending
-
2017
- 2017-11-10 US US15/809,549 patent/US20180119123A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2016262521A1 (en) | 2017-12-14 |
| WO2016183236A1 (fr) | 2016-11-17 |
| EP3294888A1 (fr) | 2018-03-21 |
| US20180119123A1 (en) | 2018-05-03 |
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