CA2984926A1 - Improved uricase sequences and methods of treatment - Google Patents
Improved uricase sequences and methods of treatmentInfo
- Publication number
- CA2984926A1 CA2984926A1 CA2984926A CA2984926A CA2984926A1 CA 2984926 A1 CA2984926 A1 CA 2984926A1 CA 2984926 A CA2984926 A CA 2984926A CA 2984926 A CA2984926 A CA 2984926A CA 2984926 A1 CA2984926 A1 CA 2984926A1
- Authority
- CA
- Canada
- Prior art keywords
- uricase
- seq
- peg
- pegylated
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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| PCT/US2016/032415 WO2016187026A1 (en) | 2015-05-15 | 2016-05-13 | Improved uricase sequences and methods of treatment |
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| CN106554948B (zh) * | 2015-09-29 | 2019-06-25 | 上海生物制品研究所有限责任公司 | 突变型尿酸酶、peg修饰的突变型尿酸酶及其应用 |
| CN112410313A (zh) * | 2019-08-20 | 2021-02-26 | 中国科学院上海药物研究所 | 一种高热稳定性尿酸酶及其应用 |
| CN112646790A (zh) * | 2019-10-11 | 2021-04-13 | 上海君实生物医药科技股份有限公司 | 改进的尿酸酶及其用于治疗高尿酸血症的方法 |
| WO2021083278A1 (en) * | 2019-10-29 | 2021-05-06 | Westlake Therapeutics (Hangzhou) Co. Limited | Engineering red blood cells for treating gout and hyperuricemia diseases |
| JP2023543045A (ja) | 2020-09-25 | 2023-10-12 | プロアブテック インコーポレイテッド | 尿酸酸化酵素－アルブミン結合体、その製造方法および用途 |
| WO2022081774A1 (en) * | 2020-10-13 | 2022-04-21 | University Of Florida Research Foundation, Incorporated | Self-assembling uricase fusion peptides |
| KR20230110281A (ko) | 2020-11-03 | 2023-07-21 | 프로탈릭스 리미티드 | 변형된 유리카제(uricase) 및 이의 용도 |
| CN114438048B (zh) * | 2020-11-05 | 2024-10-22 | 重庆派金生物科技有限公司 | 尿酸氧化酶制剂及其应用 |
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| EP2698433A1 (en) * | 2007-06-06 | 2014-02-19 | Monsanto Technology LLC | Genes and uses for plant enhancement |
| US9377454B2 (en) | 2009-06-25 | 2016-06-28 | Crealta Pharmaceuticals Llc | Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy |
| CN103184209B (zh) * | 2011-12-27 | 2015-09-16 | 拜奥生物科技（上海）有限公司 | 人精氨酸酶和聚乙二醇化人精氨酸酶及其应用 |
| CN107614007B (zh) | 2015-05-15 | 2022-03-25 | 免疫医疗有限责任公司 | 改进的尿酸酶序列和治疗方法 |
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- 2016-05-13 EP EP16797021.9A patent/EP3294322A4/en not_active Withdrawn
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| JP2021184733A (ja) | 2021-12-09 |
| SG11201708759YA (en) | 2017-11-29 |
| US20180258406A1 (en) | 2018-09-13 |
| RU2017143580A3 (enExample) | 2019-12-16 |
| MY190411A (en) | 2022-04-21 |
| JP2018515101A (ja) | 2018-06-14 |
| ZA201708507B (en) | 2018-11-28 |
| HK1252542A1 (zh) | 2019-05-31 |
| US10883087B2 (en) | 2021-01-05 |
| AU2022200104A1 (en) | 2022-02-03 |
| US20190048327A1 (en) | 2019-02-14 |
| IL255403A0 (en) | 2017-12-31 |
| RU2752497C2 (ru) | 2021-07-28 |
| AU2016265677A1 (en) | 2018-01-04 |
| AU2016265677B2 (en) | 2021-12-09 |
| EP3294322A1 (en) | 2018-03-21 |
| CN107614007B (zh) | 2022-03-25 |
| US20210254024A1 (en) | 2021-08-19 |
| BR112017024212A2 (pt) | 2018-07-17 |
| CO2017012454A2 (es) | 2018-04-30 |
| CN107614007A (zh) | 2018-01-19 |
| SG10201910522TA (en) | 2020-01-30 |
| WO2016187026A1 (en) | 2016-11-24 |
| US11098289B2 (en) | 2021-08-24 |
| KR20180002828A (ko) | 2018-01-08 |
| MX2017014547A (es) | 2018-03-15 |
| EP3294322A4 (en) | 2018-12-12 |
| RU2017143580A (ru) | 2019-06-17 |
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